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Moisturiser makes face sting

Hi all.
I'm on two prescriptions now, Differin 0.1% cream and Minocin 100mg tablets. The cream irritated my skin by making it feel really tight, and dry. My doctor told me to only leave it on for an hour, then wash it off, and eventually leave it overnight. Anyway, whenever I put a moisturiser on (I use silcock's base) , it really burns my face and it stings like hell. Would anyone know why this is??

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