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How impairing is it to the first layer?

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I know this is a sort of weird question not to understand but to answer, how impairing is accutane to the first layer of skin-epidermis's healing process?

Like, have there been any studies or similar that show red marks, scars, other sorts of marks, subcutaneous lumps, etc are more likely to be left behind from pimples, cysts, small wounds/cuts etc in the epidermis layer of the skin?

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