ForumsAcne SpecificsHormonal acneHow Long Did It Tak... Notifications Clear all How Long Did It Take For You To See Results With Spironolactone?coonie 7525 MemberMember0(@coonie7525) Posted : 06/24/2013 1:59 pm I have only been taking it for about 2 and a half weeks. I haven't seen any improvement yet. How long did it take for you? Quote Green Gables MemberMember173(@green-gables) Posted : 06/24/2013 9:48 pm 4 months before I saw anything positive (less zits, no new zits). 8 months to be clear of "lesions" (still had clogged pores and redmarks). Quote