Naturally produced testosterone in your testicles is a vital hormone thats purpose is to make you a "man". The one reason why naturally produced testosterone will never be the lead cause of acne is because one of the purposes of testosterone is to make you more "attractive" yes literally that is one of the purposes of testosterone. So a hormone thats purpose is to make you more attractive and sexually active would lead to acne is a complete contradiction.

 

Testosterone increases protein synthesis and also increases the speed your skin heals rapidly. The testosterone produced in your testicles is different from steroid injections. First of all the reason steroids cause acne is because it crashes your endocrine system and shrinks your naturally testosterone production. The testosterone produced by your body is "optimized" for you meanwhile steroid injections are not.

 

Therefor we should never blame testosterone for Acne.

 

Testosterone actually helps you fight against Acne, what causes Acne is mostly rapid insulin spikes after sugary drink/food and not eating enough fats instead only carbs.

The statement about steroids is incorrect and kind of misguiding. In a general view of steroids, yes they do cause acne. However, there is multiple subclasses of steroids and a few of these have no relevance to the pathology of acne. The one's you are referencing are called anabolic/androgenic steroids or AAS. The individual hormones in this category differ greatly in their anabolic;androgenic affinity which in turn dictates its overall plausability in acne formation.

Testosterone has a ratio of 1:1 meaning its anabolic and androgenic nature is equal. Dihydrotestosterone has a ratio of 1:2 or 1:3 depending upon reference chart. (DHT is responsible for androgen-related hair loss. has been cited as a potentiator to hormonal imbalances in females)

Also oestrogenic hormones such as estrone, estradiol, and estriol are found in humans and are major contributors to maintenence and regulation of your libido and sexuality. DHT is as well! (considering men who used DHT antagonists like finasteride for treatment of MPB commonly experience libido issues)

Insulin spikes from glucose metabolism has been a plausable factor to consider since insulin is a very anabolic hormone and can help increase the secondary secretions of GH and IGF-1. (androgenic activity is associated with an over expression from keratinocytes causing the overproduction of the protein keratin at your epidermal) Though the studies mostly cited the interactions observed into individuals with insulin resistance/Type II Diabetes.

In Type II Diabetes, the pancreas still secretes insulin normally for the most part, but receptor saturation from poor diet induced endocytsosis-mediated receptor internalization. This leads to decreased sites for tyrosine transportor to successfully bind to. Also developing insulin resistance causes the body to have a reduction to the reaction from insulin circulation.

It would be considered an increase to the threshold needed for creating an action or can be described as increasing the cell membrane negativity thereby reducing the potential action via influx from chloride ion channel pathway.

Type II Diabetes could also stem from apoptosis mediated neurotoxicity in your beta cells within the pancreas, but the mechanics denounced have been hit-and-miss.