You mean the physical pain of a throbbing pimple?
Hot compresses can help.
If its a pustule, i tend to drain them to help relieve pressure. i dont start picking and poking it, i do it the corrects and clean way which a sterilised needle. Sometimes it helps, but only if its a pustule.
Some say ice helps, but ive always found hot compresses to help me more.
Take some medication maybe to help?
I have a cyst on my chin at the moment, and it hurts everytime i move my mouth. Im using a hot compress and it is slowly taking away the pain.
good luck
Hot compresses help me tremendously and they seem to bring the pimple to a head faster, which increases healing time (although, keep that in mind before a big event - if you use a hot compress it might give you a whitehead). You could also try an noninflammatory like ibuprofen.