Combined use of microfocused ultrasound and a calcium hydroxylapatite dermal filler for treating atrophic acne scars: A pilot study.
Abstract
BACKGROUND:
An unfortunate consequence of severe acne is scarring, which can have serious psychosocial consequences. Available methods for treating acne scars have varying degrees of effectiveness.
OBJECTIVE:
This nonrandomized, retrospective pilot study assessed the safety and effectiveness of combining microfocused ultrasound with visualization (MFU-V;Ultherapy) and a calcium hydroxylapatite dermal filler (CaHA; Radiesse) for treating atrophic acne scars.
METHODS:
Healthy subjects 35-55years old with moderate-to-severe facial acne scars were enrolled. MFU-V was applied bilaterally using two transducers with focal depths of 3.0 and 1.5mm. Using a cross-hatch pattern, 75 treatment lines were applied 2-3mm apart. Immediately afterward, the same areas were injected with 1.5mL of CaHA diluted with 1.5mL of lidocaine 2% without epinephrine.Scarseverity changes were assessed by two independent physicians using the Goodman AcneScarScale at post-treatment Day 90. Subject satisfaction was assessed with a questionnaire.
RESULTS:
Treated subjects (N=10) achieved significant overall improvement in baseline acnescarseverity (P=0.002). When stratified by severity, a clear trend was apparent with the greatest improvement observed among subjects with severe scars. Subjects were very satisfied (n=9) or satisfied (n=1) with their aesthetic results. No adverse events were observed.
CONCLUSIONS:
Combining MFU-V and diluted CaHA is effective for treating atrophic acne scars.
KEYWORDS:
Atrophic acne scars; calcium hydroxylapatite filler; microfocused ultrasound; pilot study
- PMID:
- 29400587
- DOI:
- 10.1080/14764172.2017.1406606
Thank you for sharing always love new data!!!
I read this several years ago, the Chinese did this way back. It has never gained popularity. Ultherapy has a terrible rating for treatments.
This sounds like more of a study sponsored by a device company ie. Ultherapy. I have never found MFU-V effective for acne scar treatment. It is bulk heating and dare I say less controllable than a laser. RF needling is more controllable in fact for this purpose.You are basically bulk healing a area and doing a filler.
We already use filler for scarring. Subcision and Filler are a much better combo(manual methods always win).
Radiesse or liquid bone is already used for scaring, but it unfavorable as it's not reversible when there are side effects like a HA Filler. Like "more" permanent fillers do not get this unless you do well with a HA filler first a few times and like the results.
In a way I think that using filler is cheating. It's not really resolving scars, it's just disguising them.
But I wish that these "skin tightening" treatments really worked to lay down loads of new, healthy collagen. It seems to me that most of them should have the potential to help with scarring in the dermis.
It also seems that most of them, if they do anything at all, have only marginal efficacy, and many of them have the potential for disaster.
Yes, they might be stimulating new collagen, but not nearly as much as what is desired. At the same time they are burning away subcutaneous fat, which explains why some docs think these devices are best for thick-skinned ethnic patients and why other docs who rave about these devices always combine them with filler.
I have read more horror stories than triumphs. I don't think these devices are ready for prime time yet. They get released, they get approved, but they leave the testing to unwitting doctors and patients. In the meantime many lives are ruined while the doctors get richer.
I'm willing to bet that most of the improvement was from the filler, not the Ultherapy. There is no energy device that will fill in a deep pit. If anyone is cheating here, it's the device maker for trying to fool people into thinking the device is what's lifting the scar and not the filler being used.
Personally, I care more about results, and frankly fillers are way more powerful than lasers / energy devices will ever be.
Yes, Russians and even Americans have done this OFF LABEL study by Merz. BA is correct, study was funded by Merz who owns both Ultherapy and Radiesse. This was presented in the Czech Republic 2 years ago at a World Summit Merz convention.American study had a much more conservative dilution, Russian study had vvvv dilute concentrations. American study was done in California by Dr Fabri, Russian study was done in a very different environment, however conclusions and outcomes the same. Australian study in Brisbane paralleled Californian study, no conflict of interest in the Australian study, but this was off label and not blinded controlled.
As BA highlighted, an energy device with consumables is not the ideal, nor the best way to treat the majority of acne scars. Studies only confirm what experts have known for years.... if not decades.