I've never come across Picosure but I believe it's to reduce the hyperpigmentation involved from acne. Whereas the latter is using radio frequency waves to bypass the epidermis and allows the energy to induce a greater depth of injury to the scarred site. I have had many sessions with radio-frequency treatments. Results attained are good on early shallow scars; for deeper and mature scars, I honestly did not see any improvements.

Hope this helps.