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[Sticky] Scarless Healing

 
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21
(@repola)

Posted : 10/30/2013 2:49 pm

Hi folks,

I am improving my facial trauma scar with a combination of ablative and non ablative lasers, erbium 1540 and 2940.

microneedle radiofrecuency can be another option.

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(@Anonymous)

Posted : 10/30/2013 6:29 pm

Hi folks,

I am improving my facial trauma scar with a combination of ablative and non ablative lasers, erbium 1540 and 2940.

microneedle radiofrecuency can be another option.

Good luck! Hopefully you notice a difference.

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MemberMember
101
(@lapis-lazuli)

Posted : 10/30/2013 6:33 pm

Well that's great but you should really post that in another section of the forum...

Hi folks,

I am improving my facial trauma scar with a combination of ablative and non ablative lasers, erbium 1540 and 2940.

microneedle radiofrecuency can be another option.

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16
(@maldition)

Posted : 11/05/2013 2:04 pm

Time happens and no news (they promise news on 2 november) so this is a 'the hydrogel fails' sorry is not work

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(@Anonymous)

Posted : 11/05/2013 2:59 pm

Time happens and no news (they promise news on 2 november) so this is a 'the hydrogel fails' sorry is not work

I think you mean November 6th since that's when the meeting is

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73
(@seabs135)

Posted : 11/05/2013 3:56 pm

The event is a speaking event, which are fairly common that no one on here knows the exact speaking arrangement or structure to... They will do these lectures quite often. And for all anyone knows, the speakers may only have 5 minutes slotted to brief something. And there is nothing that says anyone has to announce anything other than what is already known. It may just be a common city festival...

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(@Anonymous)

Posted : 11/05/2013 4:42 pm

The event is a speaking event, which are fairly common that no one on here knows the exact speaking arrangement or structure to... They will do these lectures quite often. And for all anyone knows, the speakers may only have 5 minutes slotted to brief something. And there is nothing that says anyone has to announce anything we don't already know. It may just be a common city festival...

So seabs are you suggesting the event tomorrow might not even have any impact on this whole hydrogel situation?

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73
(@seabs135)

Posted : 11/05/2013 4:58 pm

CollegeKidd, what I'm saying is, it is a lecture and I reckon they will do these all the time and there is nothing stated that they will announce something. And people are putting to much tea leaf reading in to it. Regarding the impact, the impact has been made with the paper. Though, they may or may not announce something new, but who knows? But if they don't announce anything then that just means they haven't announced anything new.

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(@Anonymous)

Posted : 11/05/2013 5:31 pm

Ugh i'm so tired of waiting i just wanna know if the damn thing works or not! It's classified as a device so i don't see what's taking so long for human testing and why the hydrogel isn't a more known thing! I mean it's supposed to COMPLETELY REGENERATE SKIN does the world not understanding the significance of this lol

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29
(@cycloverid)

Posted : 11/05/2013 8:44 pm

While this sounds promising, how would it work - does anyone know? Would you just apply it or would you have to ablate away some skin and apply it? I'm having a hard time imagining what a procedure would look like that uses this wonder-gel.

Sorry if this has already been answered.

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(@Anonymous)

Posted : 11/05/2013 11:57 pm

While this sounds promising, how would it work - does anyone know? Would you just apply it or would you have to ablate away some skin and apply it? I'm having a hard time imagining what a procedure would look like that uses this wonder-gel.

Sorry if this has already been answered.

You would have to remove the entire scar. I'm not exactly sure how they would go about doing this because of all the blood if the scar is deep enough. Plus how would anyone know exactly how deep to go? Meaning how would they know how deep the scarring is

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5
(@hiddy-cheeks)

Posted : 11/06/2013 2:52 am

Aren't people getting ahead of themselves on this, as I understand it this is being developed as a treatment for burn injuries and ulcers, not acne scars. Those are quite different things and the researchers have said nothing about scar correction.

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101
(@lapis-lazuli)

Posted : 11/06/2013 4:36 am

So they can amputate legs but they can't take away a small scar? Also, how likely do you think it is that these scientists and surgeons when they read your post would go "Hey these guys in the acne.org make some good points. We never stopped to think about all of that! I guess it's back to the drawing boards. sad.png ". lol.gif I'm sure they know what they're doing...

 

While this sounds promising, how would it work - does anyone know? Would you just apply it or would you have to ablate away some skin and apply it? I'm having a hard time imagining what a procedure would look like that uses this wonder-gel.

Sorry if this has already been answered.

You would have to remove the entire scar. I'm not exactly sure how they would go about doing this because of all the blood if the scar is deep enough. Plus how would anyone know exactly how deep to go? Meaning how would they know how deep the scarring is

Take away skin that's injured by fire and what do you have? A wound that needs to heal. Take away skin that's scarred by acne and what do you have? A wound that needs to heal.

Aren't people getting ahead of themselves on this, as I understand it this is being developed as a treatment for burn injuries and ulcers, not acne scars. Those are quite different things and the researchers have said nothing about scar correction.

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(@Anonymous)

Posted : 11/06/2013 1:11 pm

Aren't people getting ahead of themselves on this, as I understand it this is being developed as a treatment for burn injuries and ulcers, not acne scars. Those are quite different things and the researchers have said nothing about scar correction.

I was thinking the same thing. I hope this isn't only for severe burn victims or that wouldn't make sense/be fair. All scars are the same at the end of the day, so if there's a solution to completely getting rid of them I think it should apply to all scar cases.

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29
(@cycloverid)

Posted : 11/06/2013 5:13 pm

Engineering Bioactive Hydrogels for Treating Full Thickness Dermal Wounds

Wednesday, November 6, 2013: 1:42 PM

Is anyone attending this today? I'm eager with anticipation.

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MemberMember
157
(@golfpanther)

Posted : 11/06/2013 5:49 pm

 

While this sounds promising, how would it work - does anyone know? Would you just apply it or would you have to ablate away some skin and apply it? I'm having a hard time imagining what a procedure would look like that uses this wonder-gel.

Sorry if this has already been answered.

You would have to remove the entire scar. I'm not exactly sure how they would go about doing this because of all the blood if the scar is deep enough. Plus how would anyone know exactly how deep to go? Meaning how would they know how deep the scarring is

I believe they used a hole-punch excision on the mice for the experiment. It's documented in the paper and that's what I recall reading. This method is used on humans as well.

As far as how deep to excise, skin has three layers and in the paper they excised every layer in order to create a new wound bed. They then used the hydrogel on the freshly created wound. Since 3rd degree burns (the ones given to mice for the paper) destroy all three layers of skin, you'd need to remove all of that tissue in order to have a shot at complete regeneration.

Hope this helps!

 

Aren't people getting ahead of themselves on this, as I understand it this is being developed as a treatment for burn injuries and ulcers, not acne scars. Those are quite different things and the researchers have said nothing about scar correction.

Lapis explained this well, but the idea with the hydrogel is to remove the damaged tissue through excision (e.g. all 3 layers of the skin). At that point, a wound is a wound unless the damage went beyond the 3 layers of the skin.

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(@Anonymous)

Posted : 11/06/2013 7:53 pm

 

While this sounds promising, how would it work - does anyone know? Would you just apply it or would you have to ablate away some skin and apply it? I'm having a hard time imagining what a procedure would look like that uses this wonder-gel.

Sorry if this has already been answered.

You would have to remove the entire scar. I'm not exactly sure how they would go about doing this because of all the blood if the scar is deep enough. Plus how would anyone know exactly how deep to go? Meaning how would they know how deep the scarring is

I believe they used a hole-punch excision on the mice for the experiment. It's documented in the paper and that's what I recall reading. This method is used on humans as well.

As far as how deep to excise, skin has three layers and in the paper they excised every layer in order to create a new wound bed. They then used the hydrogel on the freshly created wound. Since 3rd degree burns (the ones given to mice for the paper) destroy all three layers of skin, you'd need to remove all of that tissue in order to have a shot at complete regeneration.

Hope this helps!

 

>Aren't people getting ahead of themselves on this, as I understand it this is being developed as a treatment for burn injuries and ulcers, not acne scars. Those are quite different things and the researchers have said nothing about scar correction.

Lapis explained this well, but the idea with the hydrogel is to remove the damaged tissue through excision (e.g. all 3 layers of the skin). At that point, a wound is a wound unless the damage went beyond the 3 layers of the skin.

I'm guessing they would be able to customize the width and length of the punch hole to each scar?

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29
(@cycloverid)

Posted : 11/06/2013 10:39 pm

Wait, so did the meeting take place today? I WANT UPDATES!!!

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(@Anonymous)

Posted : 11/06/2013 11:24 pm

Wait, so did the meeting take place today? I WANT UPDATES!!!

The event took place today, but there's no guarantee that there will be an update. Best case scenario is that they somehow got investors to help fund the hydrogel. *fingers crosses*

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101
(@lapis-lazuli)

Posted : 11/07/2013 6:13 am

https://aiche.confex.com/aiche/2013/webprogram/Paper337043.html

At the bottom of that page they mention an extended abstract that isn't uploaded. I'm assuming they will at some point do so.

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MemberMember
5
(@skinregenerator)

Posted : 11/07/2013 12:02 pm

check this::

http://www.sciencedaily.com/releases/2013/10/131009132235.htm

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(@Anonymous)

Posted : 11/07/2013 4:36 pm

Very interesting and amazing, but it has nothing to do with the hydrogel! -___-

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5
(@hiddy-cheeks)

Posted : 11/08/2013 2:43 am

https://aiche.confex.com/aiche/2013/webprogram/Paper337043.html

At the bottom of that page they mention an extended abstract that isn't uploaded. I'm assuming they will at some point do so.

Where's the bit about scarless healing? All I see is: "Burn wounds treated with dextran hydrogels showed enhanced re-epithelialization, hair follicle recruitment and neovasculargenesis during the healing process."

That's so vauge as to be capable of meaning anything. Enhanced by how much? 2%? 90%? I admit I haven't read much on this, but that abstract doesn't seem like much to get excited about.

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(@Anonymous)

Posted : 11/08/2013 3:07 am

 

https://aiche.confex.com/aiche/2013/webprogram/Paper337043.html

At the bottom of that page they mention an extended abstract that isn't uploaded. I'm assuming they will at some point do so.

Where's the bit about scarless healing? All I see is: "Burn wounds treated with dextran hydrogels showed enhanced re-epithelialization, hair follicle recruitment and neovasculargenesis during the healing process."

That's so vauge as to be capable of meaning anything. Enhanced by how much? 2%? 90%? I admit I haven't read much on this, but that abstract doesn't seem like much to get excited about.

Like Seabs said, it's not a scientific document it's just an announcement for an event. So, they're not really gonna go into detail about all the scientific aspects of it. We should just trust what John Hopkins has put out, which is that the hydrogel promoted SCAR FREE skin regeneration. I just wanna know what's taking so long like this is literally revolutionary!! -___-

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MemberMember
13
(@trendycat)

Posted : 11/08/2013 5:20 am

While this isn't related to the hydrogel, it is a very interesting and promising article nonetheless. Apologies if it's been posted before:

http://www.dailymail.co.uk/health/article-2490853/Fountain-youth-gene-discovered--scientists-say-help-heal-wounds.html

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