This is my second round of accutane. I'm just beginning week 3. HATE the dry lips more than anything, but I think I found a really great combination--lip scrub from LUSH followed by Aquaphor. I use the lips scrub in the shower. It's all natural with oils to hydrate, as well. Check out LUSH online if there isn't a store near you. Aquaphor is at Walmart or drug stores.