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I actually did, my derm gave me 0.1% tretinoin so i did was on mondays and thursdays, nights i would cleanse, let my face completely dry and use my tretinoin, on the other days i do the regular DKR (sometime i feel like it i'l use the AHA but most of the time i dont really need it)with sunday being my rest day where i do no treaments or tretinoin just clease and moisturize. its been going great!