Inflammation impairs sebum quality and causes skin cells to become deformed apparently. There is some speculation that "inflammation" is already present before someone even develops acne (which usually during puberty, for most people anyway) but this is not proven.

On 5/22/2016 at 9:23 PM, Noquitter said:

Inflammation impairs sebum quality and causes skin cells to become deformed apparently. There is some speculation that "inflammation" is already present before someone even develops acne (which usually during puberty, for most people anyway) but this is not proven.

i think its the case for me as I have several inflammatory conditions. I get migraines and have really bad allergies and hormone issues.