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Omega 3, 6, and 9 Fatty Acids

 
MemberMember
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(@ndnromeo)

Posted : 03/28/2007 8:38 am

i dont know if its a placebo effect but after a week of taking 2 pills/day my oil feels less sticky. im taking this with zinc and green tea extract. i havent gotten any new pimples since ive started but it could be a fluke... sooo ill have my fingers crossed and hope this is the answer to my problema

That's pretty much what I felt in the first week or so. But then I upped my dosage from there on out, as it would kick in much faster in terms of getting your body back into balance.

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8
(@ndnromeo)

Posted : 03/28/2007 8:42 am

Sorry to sound like a broken record (it's not my intention really), but can someone answer my questions???:

.......I'm still giving the fish oil a shot, considering I haven't been taking too good care of my body or diet to begin with. I still don't have an idea how many pills a day I should be taking, considering and as I've mentioned before, I don't eat as much as I'd like to during a regular day. Probably 3-4 times a day, with all of these meals spread out pretty far. Did I mention I have an awesomely fast metabolism, which is why I've been skinny/lanky all of my life??? Are 6 pills of (1000mg, 300mg Omega-3) fish oil/day safe to take??? I figure as much that this isn't B5, where megadoses aren't as dangerous to take.

Yeah 🙂 Don't worry so much, since B5 is a vitamin, and has a RDA upper level of intake and listed side effects. Most fish oil can't give side effects unless you really overdose on it. Since it's a fat (polyunsaturated fat), you should be okay. Go up slowly, and spread the intake out. If you take it all at once you will experience a drop in blood pressure, but spread out through the day, you will be fine 🙂 I take 2 per meal... for my three biggest meals.

I hope that helps.

300 of omega in each pill x 6 = 1.8 grams. I usually get 2.X grams of omega 6 in my diet... and a good 800 mg of omega 3 in my diet (ALA though, not EPA and DHA), so I am actually over the 1:1 limit.. but it's okay, 6 a day is still not much, and I can't tell how much ALA gets turned into omega 3 that I can use.

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9
(@ayla)

Posted : 03/28/2007 8:50 am

Sorry to sound like a broken record (it's not my intention really), but can someone answer my questions???:

.......I'm still giving the fish oil a shot, considering I haven't been taking too good care of my body or diet to begin with. I still don't have an idea how many pills a day I should be taking, considering and as I've mentioned before, I don't eat as much as I'd like to during a regular day. Probably 3-4 times a day, with all of these meals spread out pretty far. Did I mention I have an awesomely fast metabolism, which is why I've been skinny/lanky all of my life??? Are 6 pills of (1000mg, 300mg Omega-3) fish oil/day safe to take??? I figure as much that this isn't B5, where megadoses aren't as dangerous to take.

I take 5-6 1000 mg, 500 mg o3 fish oil pills per day - and I've been doing very well. I think these amounts would be fine. What most of us did is map our o3:o6 intake at nutritiondata.com - then supplement to equalize our o3:o6 so that it was 1:1. Some people are supplementing with a corrective dose of approximately 2:1 (o3:o6) for a short period to get a jump of the situation. I would strongly suggest to you that you map your EFA intake and supplement accordingly.

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(@bber)

Posted : 03/28/2007 10:22 am

What I've learned from following this thread from Post 1:

There is no doubting fish oil's many benefits.

It has been found to help with brain function, high cholesterol, depression, etc.

And according to the many reviews on this thread, it will help with the overall appearance of your skin.

BUT, fish oil will not cure your acne or stop oil production.

I'm not trying to target xxndnromeoxx, but there are somethings that new readers/older readers, alike, should know about this thread. This thread started off with the name "Fish oil has stopped my oil production". xxndromeoxx made claim that oil production could be reduced with fish oil. Shortly after, it was changed to "Fish oil has stopped my acne". During this time, xxndnromeoxx corrected himself and reported that the oil production not reduced, but the same. However, he did ensure us that he no longer had acne on his face, just his back. And now the title has been changed to "Fish Oil Capsules". xxndnromeoxx's latest report is "I am almost at end of week 5, and I still have an active, and blemishes...".

I understand that xxndnromeoxx put a lot of time and effort into researching fish oil, and I want to thank you for that. However, he does have a tendency to create hype for products/regimens w/o taking enough time to test them. And this hype leads a lot of misplaced hope and mis-spent money.

With that all said, although fish oil MAY help with overall skin texture, unfortunately, for all of us people with oily skin, it is not the answer to oily skin or acne.

Im not here to jump on you. I've quoted this because its mainly what I want to address. I don't know if fish oil will cure anybody or if it'll be good for you, or the other guy. However, I am a proponent of megadosing on fish oil(I believe I am the guy running the highest doses at the moment). Am I cured from acne? No, not at all. Right now I have one active on my right cheek and one on the left. But for a guy that experienced severe cystic acne this is fucking heaven. At some point I walked into 3 different derm offices and the first thing they said was "Hi, have you considered acutane." heh.

Also I still hold that my oil production has been reduced significantly. I was one of the greasiest mofos on the planet and now oil is never a bother anymore.

I don't know about any claims made on this thread or scientifc data. I didn't start searching for scientific data until i realize that either fish oil or resveratrol(both taken for performance purposes) were having amazing effects on my condition.

All in all best of luck to all of you.

 

BBer,

Dont forget to tell people you are also taking resveratrol as well!!

This stuff is also very powerful and has benefits for acne, cancer and any inflammatory skin disease.

Ive been on fish oil for about 5 weeks now.

I just got some reveratrol and im taking 200MG a day, as well as 1200mg of curcumin and 15 fish oil pills a day. Also using Tretinoin every two or three days now. My condition is under good control with the majority of the time being very clear except for my back which i dont use any topicals on. We will see how the next month will be with my new supplements and my elimination of wheat from my diet.

 

Its on the last line I wrote Autonomous =P

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8
(@ndnromeo)

Posted : 03/28/2007 6:10 pm

I was going through a search for GLA and oil production (since I am seeing if GLA's are even more effective than Omega 3), and found:

 

We have known for a while that essential fatty acids such as gamma lenolenic acid (GLA) and certain fish oils will help promote healthy skin by modifying inflammatory pathways, skin prostaglandin hormone production and sebum production.

 

 

http://www.isabellevets.co.uk/health_advic...borrhoeadog.htm

 

Though, not 100 percent credible, I suppose it does help with sebum production like bber is experiencing. So it's good news too!

 

And that gla's and omega 3's may work alike for the same skin symptoms equally effectively?

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(@bigbeauty)

Posted : 03/28/2007 7:29 pm

I was going through a search for GLA and oil production (since I am seeing if GLA's are even more effective than Omega 3), and found:

 

We have known for a while that essential fatty acids such as gamma lenolenic acid (GLA) and certain fish oils will help promote healthy skin by modifying inflammatory pathways, skin prostaglandin hormone production and sebum production.

http://www.isabellevets.co.uk/health_advic...borrhoeadog.htm

Though, not 100 percent credible, I suppose it does help with sebum production like bber is experiencing. So it's good news too!

And that gla's and omega 3's may work alike for the same skin symptoms equally effectively?

 

Well, autonomousone can probably answer this a lot better, but GLA is an o6 and I think the DGLA that is derived from it is what is beneficial. However, when the body gets enough, too much arachidonic acid then gets converted further down the chain which is pro-inflammatory and competes with EPA in terms of the eicosanoids and prostaglandins. This might be wrong/oversimplified but I think this is the idea, see the link w/ the nice chart autonomousone has referenced before:

http://en.wikipedia.org/wiki/Essential_fat...id_interactions

Now, all that said, I think o6 is still essential for good skin to a degree, but we get too much in our diet already (I recently read a book that has a great chapter on excess o6 in the modern diet, I'll write more when I have time), hence the extra arachidonic acid. However, turns out I'm also applying GLA topically in Clearogen! However, the lotion also contains ALA, so hopefully the ratio is good (fingers crossed).

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(@mrniceguy)

Posted : 03/28/2007 7:49 pm

Ok which Fish Oil Capsules should i buy and where will i be able to buy it from and how much should i take a day? I have real oily skin and i think that's the reason why I'm always breaking out.

 

Ok so i see that romeo recommended GNC Fish Body Oils 1000mg, Softgel Capsules. Now how do i take these capsules? Do i have to eat before taking them? And how much a day? thanks

 

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MemberMember
8
(@ndnromeo)

Posted : 03/28/2007 10:51 pm

I was going through a search for GLA and oil production (since I am seeing if GLA's are even more effective than Omega 3), and found:

 

We have known for a while that essential fatty acids such as gamma lenolenic acid (GLA) and certain fish oils will help promote healthy skin by modifying inflammatory pathways, skin prostaglandin hormone production and sebum production.

http://www.isabellevets.co.uk/health_advic...borrhoeadog.htm

Though, not 100 percent credible, I suppose it does help with sebum production like bber is experiencing. So it's good news too!

And that gla's and omega 3's may work alike for the same skin symptoms equally effectively?

 

Well, autonomousone can probably answer this a lot better, but GLA is an o6 and I think the DGLA that is derived from it is what is beneficial. However, when the body gets enough, too much arachidonic acid then gets converted further down the chain which is pro-inflammatory and competes with EPA in terms of the eicosanoids and prostaglandins. This might be wrong/oversimplified but I think this is the idea, see the link w/ the nice chart autonomousone has referenced before:

http://en.wikipedia.org/wiki/Essential_fat...id_interactions

Now, all that said, I think o6 is still essential for good skin to a degree, but we get too much in our diet already (I recently read a book that has a great chapter on excess o6 in the modern diet, I'll write more when I have time), hence the extra arachidonic acid. However, turns out I'm also applying GLA topically in Clearogen! However, the lotion also contains ALA, so hopefully the ratio is good (fingers crossed).

 

Thank you 🙂 You are correct, autonomous also mentioned that previously, that's what exactly stopped me from wanting to supplement it more so. :dance:

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MemberMember
8
(@ndnromeo)

Posted : 03/28/2007 10:57 pm

Ok which Fish Oil Capsules should i buy and where will i be able to buy it from and how much should i take a day? I have real oily skin and i think that's the reason why I'm always breaking out.

Ok so i see that romeo recommended GNC Fish Body Oils 1000mg, Softgel Capsules. Now how do i take these capsules? Do i have to eat before taking them? And how much a day? thanks

Oh no no, what I meant was since that person only wanted to get it from gnc (I think it was something like that) I just said to take those.

I think the liquid form would be the best bet. If you can get that, it would be really advantageous.

I take 1.8 grams of omega 3 a day, but then again, I can't handle more than taking 6 pills daily since I start feeling a bit weird. It's all different depending on the person. But you may want to try it out yourself. But remember, it's the fact that you have to balance your omega 3 and 6 which is the most important. If you find you can't balance, try to get within 1:2 of omega 3 to 6. Which should be easy enough. 🙂

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15
(@autonomousone1980)

Posted : 03/29/2007 12:37 pm

i dont know if its a placebo effect but after a week of taking 2 pills/day my oil feels less sticky. im taking this with zinc and green tea extract. i havent gotten any new pimples since ive started but it could be a fluke... sooo ill have my fingers crossed and hope this is the answer to my problema

placebo effects can sometimes be as much as a 40% improvement, as i have seen in some studies.

Id say its a good idea too add a couple of placebos to your regemin !!!

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MemberMember
15
(@autonomousone1980)

Posted : 03/29/2007 1:04 pm

I was going through a search for GLA and oil production (since I am seeing if GLA's are even more effective than Omega 3), and found:

 

We have known for a while that essential fatty acids such as gamma lenolenic acid (GLA) and certain fish oils will help promote healthy skin by modifying inflammatory pathways, skin prostaglandin hormone production and sebum production.

http://www.isabellevets.co.uk/health_advic...borrhoeadog.htm

Though, not 100 percent credible, I suppose it does help with sebum production like bber is experiencing. So it's good news too!

And that gla's and omega 3's may work alike for the same skin symptoms equally effectively?

 

from wiki

http://en.wikipedia.org/wiki/Essential_fat...id_interactions

In the inflammatory response, two other groups of dietary essential fatty acids form cascades that parallel and compete with the arachidonic acid cascade. EPA (20:5 -3) provides the most important competing cascade. It is ingested from oily fish or derived from dietary a linolenic acid found in e.g., flax oil. DGLA (20:3 -6) provides a third, less prominent cascade. It derives from dietary GLA (18:3 -6) found in, e.g. borage oil. These two parallel cascades soften the inflammatory effects of AA and its products. Low dietary intake of these less inflammatory essential fatty acids, especially the -3s, is associated with a variety of inflammation-related diseases.

Gla can provide some benefits for sure but will never be better then epa from fish oil, they both work differently to reduce arachidonic acid, and gla supplemntation is probably something an older adult, like in their 60s, might need rather then a twenty something. Although i do every once in a while take a borage cap just to make sure i got some gla.

Heres another chart that will help you understand how the balance works and how i eicosanoids are made from efas.

if you are really hard up to improve your fat levels in your body try an ultra low omega 6 diet.

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0
(@mrniceguy)

Posted : 03/29/2007 4:05 pm

Ok which Fish Oil Capsules should i buy and where will i be able to buy it from and how much should i take a day? I have real oily skin and i think that's the reason why I'm always breaking out.

Ok so i see that romeo recommended GNC Fish Body Oils 1000mg, Softgel Capsules. Now how do i take these capsules? Do i have to eat before taking them? And how much a day? thanks

Oh no no, what I meant was since that person only wanted to get it from gnc (I think it was something like that) I just said to take those.

I think the liquid form would be the best bet. If you can get that, it would be really advantageous.

I take 1.8 grams of omega 3 a day, but then again, I can't handle more than taking 6 pills daily since I start feeling a bit weird. It's all different depending on the person. But you may want to try it out yourself. But remember, it's the fact that you have to balance your omega 3 and 6 which is the most important. If you find you can't balance, try to get within 1:2 of omega 3 to 6. Which should be easy enough. 🙂

 

So which brand are you using? And does it really help with oily skin and annoying whiteheads? Because that is really my problem right there.

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MemberMember
8
(@ndnromeo)

Posted : 03/29/2007 5:30 pm

Ok which Fish Oil Capsules should i buy and where will i be able to buy it from and how much should i take a day? I have real oily skin and i think that's the reason why I'm always breaking out.

Ok so i see that romeo recommended GNC Fish Body Oils 1000mg, Softgel Capsules. Now how do i take these capsules? Do i have to eat before taking them? And how much a day? thanks

Oh no no, what I meant was since that person only wanted to get it from gnc (I think it was something like that) I just said to take those.

I think the liquid form would be the best bet. If you can get that, it would be really advantageous.

I take 1.8 grams of omega 3 a day, but then again, I can't handle more than taking 6 pills daily since I start feeling a bit weird. It's all different depending on the person. But you may want to try it out yourself. But remember, it's the fact that you have to balance your omega 3 and 6 which is the most important. If you find you can't balance, try to get within 1:2 of omega 3 to 6. Which should be easy enough. 🙂

 

So which brand are you using? And does it really help with oily skin and annoying whiteheads? Because that is really my problem right there.

 

Yes, it does. It corrects what's essentially wrong with people who generally have acne. It's not only oil, it's the fact the dead skin within your pores do not shed and then clog with the oil, also the oil that you produce is in excess, and is too thick. It fixes this well, as it did for me, so no matter how much oil you produce, it won't clog your face, and it will simply nourish your skin like it's supposed to instead of sitting there just making you shine. I hope that helps. I'm just speaking from experience, it may be different, but I believe that if you are very strict and dedicated for a good 2 months, you'll see amazing results.

 

I was going through a search for GLA and oil production (since I am seeing if GLA's are even more effective than Omega 3), and found:

 

We have known for a while that essential fatty acids such as gamma lenolenic acid (GLA) and certain fish oils will help promote healthy skin by modifying inflammatory pathways, skin prostaglandin hormone production and sebum production.

http://www.isabellevets.co.uk/health_advic...borrhoeadog.htm

Though, not 100 percent credible, I suppose it does help with sebum production like bber is experiencing. So it's good news too!

And that gla's and omega 3's may work alike for the same skin symptoms equally effectively?

 

from wiki

http://en.wikipedia.org/wiki/Essential_fat...id_interactions

In the inflammatory response, two other groups of dietary essential fatty acids form cascades that parallel and compete with the arachidonic acid cascade. . It is ingested from oily fish or derived from dietary a linolenic acid found in e.g., flax oil. DGLA (20:3 -6) provides a third, less prominent cascade. It derives from dietary GLA (18:3 -6) found in, e.g. borage oil. These two parallel cascades soften the inflammatory effects of AA and its products. Low dietary intake of these less inflammatory essential fatty acids, especially the -3s, is associated with a variety of inflammation-related diseases.

Gla can provide some benefits for sure but will never be better then epa from fish oil, they both work differently to reduce arachidonic acid, and gla supplemntation is probably something an older adult, like in their 60s, might need rather then a twenty something. Although i do every once in a while take a borage cap just to make sure i got some gla.

Heres another chart that will help you understand how the balance works and how i eicosanoids are made from efas.

if you are really hard up to improve your fat levels in your body try an ultra low omega 6 diet.

 

That is the perfect article! Thank you, especially the "EPA (20:5 -3) provides the most important competing cascade" portion. And also, howv "Gla can provide some benefits for sure but will never be better then epa from fish oil"

Thanks! I remember seeing the chart as well, I learned a lot from that, especially the conversion enzyme D6D

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(@mrniceguy)

Posted : 03/29/2007 5:38 pm

Can you recommended me Fish Oil to buy? I'm planning on buying one today so can you please help me?

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8
(@ndnromeo)

Posted : 03/29/2007 5:44 pm

Can you recommended me Fish Oil to buy? I'm planning on buying one today so can you please help me?

Sure, I know a good number of people here use Carlson (it's in liquid form so you may have to get used to the taste). I personally use the Sam's brand: Member's Mark: which was shown to be about as good as Twin Labs. (These are the capsules, mine don't give me fish burps). They apparently seem to be working as well. But if you can, go with liquid, it's more efficient and in it's purest form without fillers in the pills.

http://www.carlsonlabs.com/product_detail....mp;categid=03a9

You can get that one at GNC, I believe. I am not 100% sure.

Let others chime in and tell you what they use. I know arivienta uses this one. I am not sure what autonomous uses, but it's worth looking into.

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MemberMember
0
(@bber)

Posted : 03/29/2007 5:50 pm

Can you recommended me Fish Oil to buy? I'm planning on buying one today so can you please help me?

I used to use Walmar'ts generic brand one and now im using Sam's Members Mark.

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MemberMember
0
(@mrniceguy)

Posted : 03/29/2007 5:53 pm

Can you recommended me Fish Oil to buy? I'm planning on buying one today so can you please help me?

Sure, I know a good number of people here use Carlson (it's in liquid form so you may have to get used to the taste). I personally use the Sam's brand: Member's Mark: which was shown to be about as good as Twin Labs. (These are the capsules, mine don't give me fish burps). They apparently seem to be working as well. But if you can, go with liquid, it's more efficient and in it's purest form without fillers in the pills.

http://www.carlsonlabs.com/product_detail....mp;categid=03a9

You can get that one at GNC, I believe. I am not 100% sure.

Let others chime in and tell you what they use. I know arivienta uses this one. I am not sure what autonomous uses, but it's worth looking into.

 

Thanks alot man.Now how many times a day do you use this? Are you supposed to add this to a drink or take it alone?

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8
(@ndnromeo)

Posted : 03/29/2007 6:10 pm

check first post, it all varies depending on the person and your diet. It will give you a general idea on what to do. I personally take 1.8 grams because I don't need that much to balance my omega 3 to 6, some people use more because they eat more than I do etc.

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9
(@ayla)

Posted : 03/29/2007 6:42 pm

I use Carlson's Capsules - see sig. I can't stomach the straight oil.

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MemberMember
0
(@mrniceguy)

Posted : 03/29/2007 6:51 pm

http://www.mypatienteducation.com/memaom3fioil.html

 

Well i found Member's Mark Omega 3 Fish Oil 1000 mg 300 softgels. What you think of those?

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0
(@anony-2)

Posted : 03/29/2007 7:34 pm

Gla can provide some benefits for sure but will never be better then epa from fish oil, they both work differently to reduce arachidonic acid, and gla supplemntation is probably something an older adult, like in their 60s, might need rather then a twenty something. Although i do every once in a while take a borage cap just to make sure i got some gla.

Not true....someintheuk posted before about how he was able to get rid of his acne with GLA. he had tried fish oil in the past and it didn't work for him as well as GLA.

i'm not saying i have the answer though. I have been taking fish oil (up to 5g/day) for six weeks. And about 600 mg of GLA. My diet for the last 4 weeks has been pretty much paleo. i still have tortilla wraps once in a while but hardly any carbs other than that and green vegetables and a little fruit, no dairy,wheat etc. About a week and a half ago my skin was very good...no active spots on my face, just one or two below my jawline/under chin. but for whatever reason i broke out bad about 5 days ago in areas on my face i hadnt broke out in in months. big cystic bumps too. if i don't improve a lot in the next month, i am probably going to go on accutane. i didnt ever want to consider it before but after doing all these things and it seems i'm still not getting significant improvement. sorry to be the bearer of bad news to those hoping fish oil is the cure. it may be for you...but it probably isnt for me.

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15
(@autonomousone1980)

Posted : 03/30/2007 2:31 am

Gla can provide some benefits for sure but will never be better then epa from fish oil, they both work differently to reduce arachidonic acid, and gla supplemntation is probably something an older adult, like in their 60s, might need rather then a twenty something. Although i do every once in a while take a borage cap just to make sure i got some gla.

Not true....someintheuk posted before about how he was able to get rid of his acne with GLA. he had tried fish oil in the past and it didn't work for him as well as GLA.

i'm not saying i have the answer though. I have been taking fish oil (up to 5g/day) for six weeks. And about 600 mg of GLA. My diet for the last 4 weeks has been pretty much paleo. i still have tortilla wraps once in a while but hardly any carbs other than that and green vegetables and a little fruit, no dairy,wheat etc. About a week and a half ago my skin was very good...no active spots on my face, just one or two below my jawline/under chin. but for whatever reason i broke out bad about 5 days ago in areas on my face i hadnt broke out in in months. big cystic bumps too. if i don't improve a lot in the next month, i am probably going to go on accutane. i didnt ever want to consider it before but after doing all these things and it seems i'm still not getting significant improvement. sorry to be the bearer of bad news to those hoping fish oil is the cure. it may be for you...but it probably isnt for me.

 

Well as for the stuff i posted thats pretty much where the science stands but i will consider anybodys claims of benefits from gla. but then again i hear some pretty outlandish claims on this site all the time, so that dont mean very much to me, but ill take a mental note.

I would like to recommend that you still use topicals because you will need them with the fish oil. I would also suggest you take at least 15 a day and eat salmon 3X a week, but the main idea with fish oil is to reduce your omega 6 intake and reach a ratio of around 1:1 of o6/o3.

dietary fat is a very powerful substance that interacts closely with your genetics, in fact alot of food does but fats especially and efas even more so. I believe the benefits of achieving a ratio of 1:1 are perhaps going to continue slowly for perhaps up to a year of consistent use.

with the majority of the benefits to happen in the first 3-6 months. Because when your cells replicate themselves they interact with whats in your diet and the genes will adjust their instructions on the cell according to that environment and certain genes will be either more strong or more weak and the behavior of all your cells will improve. it will most likely improve your acne condition but there havent been any studies for acne and fish oil so i dont think it will cure you but give it a full three months of doing it right before you knock it.

You must continually bathe your cells in a good diet for many months to really make an impact. Nutrigenomics is a new science that deal with studying the exact genetic effects of food and is going to revolutionize the way we treat diseases. Our food will basically be our medicine and distinct diets will be precribed to people according to their dna. Phytochemicals have the ability to reprogram genes that have been knockout and repressed or over exxpressed that is why many phytochemicals are being researched for cancer.

Curcumin is one of them as well as resveratrol.

I just started taking curcumin and resveratrol for their ability to improve abnormal inflammatory responses and abnormal cell proliferation at a genetic level particularly cox-2 and nf-kappa b http://en.wikipedia.org/wiki/NF-kB#NF-.CE...._Other_Diseases

Am J Pathol. 2005 Jun;166(6):1691-9. Links

Inflammation and extracellular matrix degradation mediated by activated transcription factors nuclear factor-kappaB and activator protein-1 in inflammatory acne lesions in vivo.Kang S, Cho S, Chung JH, Hammerberg C, Fisher GJ, Voorhees JJ.

Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA. [email protected]

Acne is the most common skin disease, causing significant psychosocial problems for those afflicted. Currently available agents for acne treatment, such as oral antibiotics and isotretinoin (Accutane), have limited use. Thus, development of novel agents to treat this disease is needed. However, the pathophysiology of acne inflammation is poorly understood. Before new therapeutic strategies can be devised, knowledge regarding molecular mechanisms of acne inflammation is required. We report here that transcription factors nuclear factor-kappaB and activator protein-1 are activated in acne lesions with consequent elevated expression of their target gene products, inflammatory cytokines and matrix-degrading metalloproteinases, respectively. These elevated gene products are molecular mediators of inflammation and collagen degradation in acne lesions in vivo. This new knowledge enables a rational strategy for development of pharmacological agents that can target the inflammation and matrix remodeling that occurs in severe acne.

some stuff to check out.

http://www.ncbi.nlm.nih.gov/entrez/query.f...l=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.f...l=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.f...l=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.f...l=pubmed_docsum

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0
(@bobby-digital)

Posted : 03/30/2007 8:00 am

MAN my face has improved this week.

 

Thatll be all.

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MemberMember
8
(@ndnromeo)

Posted : 03/30/2007 10:24 am

MAN my face has improved this week.

Thatll be all.

Good, but do remember, give it 10 weeks, your body takes time to start using what it gets in. In 10 weeks, the omega 3 levels in your body should be ideal to do what it's supposed to. Don't give up easily, it takes time. It will gradually get better, but you will still have ups and downs. The second you see a 'down' don't associate it with it relating to the fact that 'it's not working' or anything like that. Be logical, and reasonable, and you will be good to go.

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15
(@autonomousone1980)

Posted : 03/31/2007 2:01 pm

Here is the nutrient profile for oysters, its actually quite surprising how jam packed these things are with vitamins and minerals, and also a great source of omega 3s.

 

lots of vitamin E and D and B12

 

I remember i used to eat these with hot sauce and they were pretty tasty.

 

http://www.nutritiondata.com/facts-C00001-01c215Z.html

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