This stuff combined with oral erythromycin saved me. Had severe acne with pretty bad cysts and nothing else could get rid of them. Didn't notice an initial breakout because my acne was so bad an I dint really pay attention! Funny thing was I probably used it incorrectly. I would lightly wash my face with a face cloth and hot water then apply like 3 times as much as you're supposed to. I don't recommend this btw. It did burn initially but it didn't really bother me as my face was so painful already and everything else I'd tried for the past 5 months had burned like hell as well. Problem is that I kept using it for about a month or 2 after I got completely clear and it would no longer make my skin drier but I would wake up with oily skin and some little whiteheads/crusty bits on my nose (see my 07/09/14 post for the full story) and now I'm dealing with what I think is a different escalated problem. Long story short it can be a lifesaver and definitely worth a try but be careful as over use can leave you open to other problems.