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German Gary

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  1. Sorry for taking so long to reply, I got distracted. Yes, taking antibiotics will help to reduce the initial breakout. While it's likely that you will still see some flare-up, it shouldn't be as bad as if you were just on the topical isotretinoin. It will take a similar amount of time to get results, but you shouldn't get such a big worsening of your acne initially. While the time it takes to get clear probably won't change, your acne on the way to getting clear shouldn't be as bad.
  2. I was on topical isotretinoin quite recently, marketed under the brand name Isotrex. How much do you know about it? It's a retinoid that encourages an increased rate of skin turnover. Basically, it makes your layers of skin cycle through quicker, thus helping to prevent acne. It can be irritating to your skin, and you are likely to experience redness and drying. Your treatment will likely last somewhere between 3 and 6 months, and it will be around 6 weeks before you see real improvement if i
  3. I was on doxycycline (in addition to topical retinoids) for 7 months. I was pleased with it - it certainly didn't clear my acne, but it stopped me getting massively inflamed acne. I used to get almost cyst-like pustules under the skin, but doxycycline stopped those. I was pleased with it, but I took it as a supplement to a topical retinoid, and when the retinoid failed, I ended up on isotretinoin. I think of doxycycline as more of a maintenance product - it stops inflammation while you're on it
  4. I'm on both 400mg erythromycin twice a day and isotretinoin, but I haven't experienced an increase in the frequency of visits to the bathroom. Are you sure this is the erythromycin? What sort of dosage are you on? If your acne is mild, then no, I wouldn't recommend isotretinoin (Accutane) for it. Accutane is extremely dangerous, which is why it is so hard to justify using it for most people. If your acne is only mild and looking "all right" at present, then the risks FAR outweigh the benefits
  5. Differin is adapalene, and I think Retin-A is tretinoin. You could google both of those names if you wanted. Both have similar side effects, but I believe that Retin-A is the stronger, but less gentle, retinoid. Being on Differin shouldn't be too much different, and hopefully your side effects will be reduced.
  6. With regards to using Differin or Retin-A with your isotretinoin, that is rare, but presumably safe if a nurse suggested you do that. Topicals generally don't penetrate the skin in large quantities (I think that's from studies that suggest Differin is only present in blood plasma in trace amounts), so there isn't an issue with buildup. However, I did read a study yesterday that showed adding a topical retinoid to oral isotretinoin did nothing to help acne.
  7. What is your mass? They recommend that you take a cumulative dose of 120-150mg per kg of body mass to help avoid a recurrence of acne. If you've been on 55/55/60/60mg for four months, by my logic you should have approximately 6900mg total, which means that you've passed the threshold if you are 57.5kg or below. Keep in mind that the 120mg/kg is approximate. As for the success rate? I can't remember the specific figures quoted, but most don't require a second course. A lot of people do experien
  8. I am sorry to hear of your predicament. The recommended cumulative dose is 120-150mg/kg, and by my calculations, your dosage after seven months should be around 148mg/kg. In terms of dosage, I think you should be fine. Hang in there, I hope your acne improves soon!
  9. Decreased night vision is listed as a possible side effect of Accutane. I don't hear of many people getting it on this board, but I would still be wary. If you do develop issues while on the drug, is it possible for you to get public transport to work? You would be unlucky to have issues with night blindness, but it is something to watch out for. Yes, you have to be on birth control regardless of your current level of sexual activity. It's a precaution that you will have to take ... Just becaus
  10. I've been on both 0.1% Differin and 10% benzoyl peroxide. For me personally, I found the benzoyl peroxide at that concentration to be more drying than the Differin - though individual results will vary. I am one of the lucky few that got incredibly oily skin from using Differin, so I'm probably not the most impartial person to ask.
  11. My breakout subsided somewhere around week 6, and I started to see small improvements around week 9 or 10. Sadly, it went stagnant around there and I ended up on Accutane, but I wish you luck. Most people seem to find Differin works well for them, so try to be positive and hopefully before you know it, you'll see improvements.
  12. Genetics. I'm unlucky in that I am plagued, like the rest of my family, by acne, but lucky in that I don't seem to be able to aggravate it. I don't really get stressed easily, but I can get by on 5 hours of sleep while eating anything and still not break out. While I can't aggravate it, it is constantly moderate and I am presently on Accutane.
  13. I started isotretinoin (Accutane) slightly over a week ago, but not before doing a lot of research into it. Isotretinoin is an extremely powerful drug. I'm sure that you have read all of the horror stories of the lasting joint pains, low libidos, mood swings and so on. However, isotretinoin is extremely effective for most people - even on 20mg on alternating days, my skin is drier than it ever was on topical retinoids and I'm actually seeing flaking skin for the first time in years. If your d
  14. We have progress! I visited my dermatologist yesterday, and I didn't even have to bring it up. He suggested it outright, and prescribed me 20mg/day (on alternating days for the first two weeks, then daily from then on) and erythromycin. The dermatologist does not open on Fridays so I have to wait until Monday to get his permission to start (pending the blood test results, they will be ready by Monday), but it looks like it's all go from Monday.
  15. The elimination half-life of isotretinoin is 21 hours, with a standard deviation of 8.2 hours. Basically, within a week of coming off it, you will have less than 1% of a dose left in your body. I would advise caution however, as some of the products of isotretinoin have longer half lives. Doctors say to use contraception for at least one month after discontinuing Accutane, so you should definitely be safe by then.