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  1. Im dealing with the same thing. Finally after a year on 75mg spiro I added an antibiotic and Ive had great results. I honestly never got clear on the spiro alone. So this summer I started noticing the mustache too. I read some other people associating it with spiro. My derm says thats not it but Im not sure. So I lowered the dose to 50mg and started using 100spf on mustache. It is fading. I also got a rx of Tri-luma. Now three weeks after lowering my spiro my face is breaking out. So depressing.