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  1. Hi... I started using the gel Epiduo on September 10. It got rid if all the little zits I had on my chin and left cheek very quickly. I continued to use Epiduo once a day at night, using a small pea sized amount to the areas of my face. My face was very clear with only a little zit here and there for a month.. so I continued the epiduo treatment. Then 3 days ago, I suddenly break out with underground acne which turns into cystic acne the next day. They have spread all over my cheeks and my chin