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Everything posted by fchawk

  1. If your body is converting beta carotene into vit A it means your body wants it. It is also why some people get mixed results from vitamin D. Isotretinoin can cause vit D deficiency, and certainly causes symptoms of vitamin A toxicity, but also symptoms of vit A deficiency, and going too hard on the vit D and exacerbate vit A deficiency. Just take some vitamin A, D, E and K so you are not defiicient in any of them, don't fully avoid any of them. The reason I talked about cayanne pepper is I
  2. https://www.ncbi.nlm.nih.gov/pubmed/22431270 "In this case report, the authors describe a 48-year-old male who complained to his primary care physician of abdominal discomfort and yellow/orange skin discoloration. Physical examination was normal except for some mild mid-abdominal discomfort (no observed skin color changes). An abdominal CT scan indicated a colon that was full of stool. Laboratory studies indicated elevated liver enzymes. Upon further questioning, the patient reported ingest
  3. Ahh, I'm on the "faction" that you shouldn't avoid vitamin A, especially beta carotene, as it is impossible to get vitamin A overdoses from beta-carotene(Though significant dosages can cause issues unrelated to vitamin A), and the reason I believe this is because Isotretinoin is a derivative of vitamin A, and can actually cause symptoms of vitamin A deficiency, such as night blindness, and I wouldn't be surprised the reason some of us got adverse reactions is because we were initally low in vita
  4. Hi y'all, think I'm doing pretty good with anxiety, mind fog, and depression. However, the ED still looms at large. I can get hard, but go soft in about 10 seconds. Back in November I did some fasting, a total of 12 days with 2 days keto in the middle (and had been keto for 6 weeks preceding this), and after that I got morning wood for 2 months straight, and libido seemed stronger. While I was fasting I would just have electrolytes, bi-carb soda, and cayenne pepper. Eventually it went back
  5. My main point is don't avoid it and vitamin A, because Isotretinoin is not vitamin A, and infact can cause vitamin A deficiency. Isotretinoin-Induced Night Blindness https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533586/ Oral isotretinoin, neuropathy and hypovitaminosis A https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2230.2008.03171.x The second link has case studies which suggests between Vitamin A deficiency pre treatment and suffering depression due to accutane, and by suppleme
  6. I've recently talked to others who’s PRSD makes mine pale in comparison, despite the fact that it was still completely life changing. I fantasised about suicide, but I guess I could still live if I lowered my expectations low enough, such as by dropping out of Uni and accepting I would never have a sexual relationship, and that I would never be particularly happy or successful, etc... while post recovery, I I think I can now achieve a good life, going to Uni, dating, having fulfilling relationsh
  7. I too wouldn't recommend Accutane. While the risk isn't great, there certainly is a risk of long term side effects. While I wasn't told these potential side-effects before I went on it, I was told it may affect my growth. I was already 16 years old and 6'4, so I didn't mind, but at 13 it would certainly be something to consider. Lastly, for some people this is worth taking, I have several friends who took it and don't regret it, but they all had very severe acne. Personally I regret taking it
  8. Not really, I did start getting a bit of acne back, so I occasionally get a few pimples, but I am always pretty dry so I moisturise these days, or my skin gets kinda flaky, especially after hot showers
  9. Isotretinoin (cis-13 retinoic acid) usually composes of ~2% of the retinoids in your body. During treatment it composes of 98+% of the retinoids in your body, as you are taking it at 100x your usual vitamin A dose. This is how it hijacks retinol metabolism
  10. Creatine and zinc would be the best safe/accessible supplements going by your theory.
  11. The specific retinoid poisoning Isotretinoin induces has been shown to cause Vitamin A deficiency, not vitamin A toxicity. Isotretinoin-Induced Night Blindness https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533586/ That is why I megadosed it as my first attempt in treating long term accutane sides. The first week I felt good, thought more must be better, and ended up poisoning myself. So don't megadose, however taking a normal dose is fine, and avoiding it would be counterproductive I think.
  12. A spiel about Olive Oil, its pretty good shit, as is fish oil, and they are both cheap . Extra virgin olive oil improves learning and memory in SAMP8 mice.https://www.ncbi.nlm.nih.gov/pubmed/21955812Neuroprotective effect of olive oil in the hippocampus CA1 neurons following ischemia: Reperfusion in micehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724295/Olive oil-enriched diet reduces brain oxidative damages and ameliorates neurotrophic factor gene expression in different life stages of rats.
  13. Sorry for the super late reply. If you can find some vitamin k and a multivitamins that would help, just one a day for a month or two, and on top of that creatine and fish oil will help as well. Vitamin k helps regulate your retinoic acids, and a multi will help replenish any nutrients that have been depleted by the Retinoic acid imbalance. The creatine and fish oil will help repair any ill effects on the brain and mood If you are not too busy try implementing exercise and mindfulness meditati

  14. Take vitamin D and K to begin with, that will help rebalance your retinoids. Anxiety is probably one of the main causes, as Accutane completely messes up your stress and sex hormones, so right now your body probably feels a tonne of stress. People who take such a limited dose recover much better, and one of my friends took 80mg for 15 months and he is good now, though it knocked him around for a fair bit.

    One of the ironic things about accutane is it makes your body react poorly to stress, then creates a fuckton of it.

    My full recovery advise is:
    "Buy creatine, fish oil, coq10, zinc, multivitamins and a decent protein powder, take the recommended dosages for all of these, and try to meditate for 20 minutes a day"(if its early days take some k2 and vitD as well, that will get your retinoids in check post tane)

    Anyway, even if you are a random healthy male the things I've recommended would only improve your health, all would probs be available if you went to your local discount chemist 
    1. Chronic stress induces persistent changes in global DNA methylation and gene expression in the medial prefrontal cortex, orbitofrontal cortex, and hippocampus. https://www.ncbi.nlm.nih.gov/pubmed/26946265 Chronic stress is associated with a plethora of cognitive symptoms such as emotional dysregulation and impaired executive function that have been attributed to modifications in neuroanatomy in the orbitofrontal cortex (OFC), medial prefrontal cortex (mPFC), and hippocampus (HPC)(...)In general,
    2. Does oral coenzyme Q10 plus NADH supplementation improve fatigue and biochemical parameters in chronic fatigue syndrome? https://www.ncbi.nlm.nih.gov/pubmed/25386668 Chronic fatigue syndrome (CFS) is a chronic and extremely debilitating illness characterized by prolonged fatigue and multiple symptoms with unknown cause, diagnostic test, or universally effective treatment. Inflammation, oxidative stress, mitochondrial dysfunction, and CoQ10 deficiency have been well documented in CFS. W
    3. Here is the google docs with all the extra info again. https://docs.google.com/document/d/1gGkP_NQ8tmYkOADlG2VuEX17YvQJKgnfcEtgy5_6y7c/edit
    4. These are the potential side effects of brain damage. Many display a number of these symptoms. It wouldn't be a far cry to say nearly all symptoms displayed here branch from the symptoms of brain damage (ie. Lipid levels being affected by the systemic metabolic dysregulation and neuroendocrine due to the brain changes caused by accutane) Traumatic brain injury: a disease process, not an event. https://www.ncbi.nlm.nih.gov/m/pubmed/20504161/ “Traumatic brain injury (TBI) is se
    5. Serum Biotin Levels in Women suffering Hair Loss https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989391/ "Of the women complaining of hair loss assessed for serum biotin levels, 38% had values consistent with biotin deficiency (<100 ng/L) and 13% optimal (>400 ng/L). In the women in whom trichograms were performed, both groups (biotin deficiency and optimal levels) demonstrated diffuse telogen effluvium in 24%. Therefore, the trichogram is not helpful in detecting hair loss relati
    6. Curing Accutane's Long Term side effects Hey, I am a 22 year old who suffered from Accutanes side effects since I was 16, and I think I am cured, though for me while sexual dysfunction was the side effect that made me notice accutane had affected me, it was not the only side effect. The route to curing my own side effects was by using nutrition and supplements, as well as meditation, to undo the damage accutane did to my brain. Personally I believe Accutane causes its negative side effect
    7. Haha, I find the majority of my protocol easy, thats why I am mad not more people are doing it! The hardest things to do are the keto diet and meditation, which are optional, all the rest take less than 5 minutes out of each day, and there is no reason to not do it! As for hyperbaric oxygen therapy, it obviously helps a lot, its just I am just a poor uni student and I can get most of the benefits in inexpensive ways anyway, so I don't mind that I can't do it Hyperbaric oxygen therapy promotes
    8. I keep a diary of my mood, if I miss a few days in a row I feel worse, creatine being one of the main things that I notice the quickest, and multivitamins help a lot as well. That said, if I don't take zinc, fish oil etc for a while, I notice I feel better once I resume taking it. None of my dosages are especially high, because no point taking risks. Creatine 5-3g per day Zinc 1 tablet a day Magnesium 2 tablets a day, one at morning, 1 at night Multivitamin 1 tablet a day Vitamin D 3-5000
    9. Didn't know any of you had tried it, as I haven't seen anyone mentioning taking creatine, fish oil, zinc, etc on a regular basis. I haven't tried hyperbaric stuff, although I am sure it would help and probably would do it if it was easily accessible/inexpensive, and I also haven't tried the deep brain stimulation, though I haven't looked into it enough to know whether I would do it even if I could right away. At the same time I feel I am better so I am not pushing too hard to try more things
    10. When you suffer a TBI, the consequences are often delayed. With those NFL players usually they finish their career and are fine for a while, and often it is not not until well after retirement that those NFL players begin to suffer the more deleterious effects of brain damage, such as memory problems, depression, mood swings, endorconology problems etc. The fact is that Accutane causes brain damage, and is scientifically proven to do so. It obviously doesn't do it by hitting you over the head,
    11. Seven months ago I made a post describing the cause of accutanes symptoms and how to cure them. I started it 4 months before I made that post, so it had been nearly a year. I stand by my cure and statements, I fully believe I am cured, though thats not to say its left it scars. I also feel I am ready to move on with my life, which I was far from being able to do 12 months ago, and I am optimistic about my future, as I feel I might well live past 90 with mind and body intact, whereas not so long