Hi Courtney, I am taking 100mg Spironolactone too. It has taken about 4 months for my skin to clear. My skin was sooooo bad when I started taking Spiro, I have never been so spotty in my life so Spiro definitely makes skin a whole lot worse before it gets better. I was on the verge of giving up so many times but I wanted to stick it out and I'm soooo glad I did. You must be prepared for your skin to get significantly worse for a good while before it gets better but it will get there. For me t