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sepsi

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Everything posted by sepsi

  1. Yes, you are right that there are problems with the rabbit ear model and it doesn’t accurately depict what happens on human skin. If this hypothesis/theory relied solely on the rabbit ear model, I wouldn’t even bother writing about it. But there are also human studies that show high levels of lipid peroxides in the earliest stages of a pimple. This happens even before the bacteria has colonized the pimple. So there are many researchers thinking P. acnes bacteria doesn’t actually cause or trig
  2. Oopps, sorry. For some reason the URLs contained full stop and comma characters. Here are URLS that work: http://onlinelibrary.wiley.com/doi/10.1111/ijd.12002/abstract http://www.ncbi.nlm.nih.gov/pubmed/7657446 http://onlinelibrary.wiley.com/doi/10.1111/j.1468-2494.2008.00479.x/abstract So there is evidence that these vitamins and antioxidants both penetrate the skin (when in a properly formulated solution) and can reduce acne - often as much as BP or topical antibiotics. I also don’t mean
  3. I’m the person who wrote the post, so perhaps I can chime in here. Everything in that post is backed by scientific research, I didn’t actually pull the statements out of my arse. I didn’t specifically cite studies showing the effectiveness of topical antioxidants in acne, but here are a few well controlled studies. Vitamin C Ruamrak et al. demonstrated good efficacy for 5% SAP lotion: http://onlinelibrary.wiley.com/doi/10.1111/j.1468-2494.2008.00479.x/abstract. Woolery-Lloyd et al. demonst
  4. I'm the person who wrote the article on milk and acne on AcneEinstein.com. Not to rain on your parade, but I'm not aware of any reason why cheese and ice cream would be less acnegenic than milk. In fact, I think they can be more acnegenic because they are concentrated forms of dairy (at least cheese). Yogurt may, and I emphasize the word may, have less of an impact because during the fermentation process bacteria consume a lot of the IGF-1 hormones in the milk. That said, yogurt still has whe
  5. Nobody can really say how much damage a course in antibiotics causes. To my knowledge it has never been thoroughly studied. I looked into this once, and the papers on this generally note that the gut microbiota is fairly stable and bounces back after a disturbance (such as antibiotics). Many studies note that the microbiota had rebounded back within a few weeks of finishing the antibiotics, but I'm not sure that's the whole story. The problem is that scientists have a limited ability to detect
  6. The only thing this proves is fallacious logic. Diet for acne is less about eating healthy and more about avoiding your specific trigger foods. Of course it helps if you avoid high GI carbs and dairy products, but there's rarely the need to get into extremely healthy diets. As I mentioned, I can go on a McD binge and probably not see a pimple on my face until a few weeks later. But [cencored] help me if I eat an onion, apple or some other 'healthy' foods I know will trigger a breakout for me.
  7. Unfortunately it's you who is both dogmatic and demonstrably wrong. There has NEVER been any good quality scientific evidence that diet does NOT affect acne. The myth was born from a few very sloppy studies in the 60s and 70s. Studies that even your high school science teacher would fail you today. Unfortunately, and I still can't understand why, those very bad quality studies were enough to persuade dermatologists that diet has no effect on acne. And most have not changed their stance despite
  8. At least the title of this thread was correct, lol..
  9. No! Fish oil and other antioxidants, such as vitamin C and E, can offer some sun protection, but in the studies I've seen they show moderate effect but I wouldn't trust them as sun screens. If my memory serves me right some studies showed that antioxidants can double the amount of sunshine skin can take before it burns. So they can help, but I wouldn't count them as sunscreens.
  10. There are also a few other green tea studies. The problem is that none of them are definitive. The study you referred was mostly in vitro, though it also had an in vivo part. These studies are interesting and provide some evidence for green tea and EGCG but the problem is that they don't have proper controls. Once we see a few studies with 100 or so participants that compare EGCG cream to BP head to head then I can say that there's reasonably good evidence for it. Such studies exists for vitamin
  11. I'm not arguing against the statement that BP has side-effects, or that it's an oxidizing agent and causes oxidative damage in the skin. I argue against black and white thinking that's so prevalent here. I argue against statements like 'BP causes oxidative damage, therefore it's automatically bad and should be shunned'. Here's the point that argument misses. ACNE itself causes a lot of oxidative damage on the skin. So if something reduces acne it most likely reduces inflammation in the skin.
  12. People put way too much faith into diet being able to cure acne. It can help, but it's far from be-all-end-all cure. There's a connection between gut issues and skin problems. From what you've said, it sounds like you have some serious digestive issues, perhaps due to not having a gall bladder. Have you noticed (or paid attention) any connection between how your gut is doing and your skin? Anecdotally, I always get get some fresh pimples when I eat something my gut doesn't like.
  13. This forum is also filled with people who haven't made much progress with their acne in years. So not much of an argument.
  14. You are jumping the gun. While I agree that the evidence suggests diet affects acne, it's far from conclusive scientifically speaking. For example, so far there are no intervention studies on dairy. All the studies are epidemiological and cannot say anything about the direction of causality. For the dairy-acne connection to be shown conclusively we need studies that show unambiguously that reduction in dairy intake leads to reduction in acne. NO such studies are done. Some such studies are don
  15. I'm not sure that anyone knows this yet. It could be that eating too many calories is one cause of insulin resistance. Fat mass can also reduce insulin sensitivity, so eating fewer calories starts to reverse that.
  16. There's little evidence that BP, when used properly, causes any harm. And just like every other medicine out there, BP has both positive and negative effects. The art of medicine comes in choosing medicines that do more good than harm. If BP reduced your acne, then you are among the minority. The other sections of this forum are filled with people who say that BP indeed has reduced their acne and skin redness. Not to mention tens and tens of clinical studies that show efficacy from BP. W
  17. There's some evidence to show that people with inflammatory acne have significantly lower levels of antioxidant vitamins and minerals. Most likely this is because of acne - rather than the cause of acne. There's also evidence that supplementing with antioxidants can help, especially zinc but also with an antioxidant blend that contains vitamin B3, C and E.
  18. Scientifically speaking, the connection between diet and acne is anything but settled. There is more evidence that diet affects acne than it doesn't. But the studies linking diet to acne are not conclusive. The dairy-acne studies are all epidemiological and as such can't say anything about causation. There is better evidence for sugar and high GI carbohydrates causing acne, but even that could be better. Most of it comes from the same researchers, so there's need for more independent replicati
  19. I think it's a little simplistic to shun away from BP just because its oxidizing effect. Yes, inflammation is very bad for the skin and probably the very thing that triggers the acne formation process. At the same time BP can reduce inflammation in the skin. It destroys the bacteria that escalate inflammation and also the cells that initiate the inflammatory process in the skin. Not to mention the fact that BP reduces acne and redness of the skin. Though, when used improperly, it can also d
  20. Caloric restriction has been shown to improve insulin resistance and reduce inflammation, both of which are good for acne. When I was dieting to lose some weight I also noticed that my skin was less oily during that time. Less insulin = less oily skin for me.
  21. As Omnivium mentioned, you can't generalize from one group of people to another. Topically applies zinc has at least some 5-alpha reductase activity. It's also one of the few supplements where there's evidence to show it's effective in acne. BBC recently reported about a study that showed zinc can keep immune system in check. http://www.bbc.co.uk/news/health-21372790 This could explain why zinc works for acne.
  22. Makes sense. DHEA and DHEAS levels are quite often linked to acne. It's also one of the testosterone precursors and gets converted all the way to DHT in the skin.
  23. Sorry for my late reply. I haven't had much time to visit the ORG lately. For the past 4 months I've been busy researching and writing, or updating, my book. So glad to get this monkey off my back I'm not a cosmetics chemist, so I can't give you authorative answers. But I think there are 2 reasons why antioxidants don't degrade in creams. One is that the manufacturers add stabilizers and preservatives, such as vitamin C. Another one is less exposure to the elements. One reason why antioxidant
  24. I noticed that somebody asked about how long this kind of toner stays good. A while back I looked at some research related to this. Unfortunately the catechins in green tea degrade quite rapidly. Under normal conditions you would find at home 50% were gone within the first 7 hours. Now, that's 50% starting from a lower concentration than what you get with so many teabags in a cup of water. Regardless, I wouldn't expect any tea to retain antioxidants for very long. You can extend the shelf-life s
  25. Stupidity burning thermonuclear hot... http://scienceblogs.com/insolence/2008/08/07/a-fungus-among-us-in-oncology/
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