Skin Not Responding To Any Prescriptions in Prescription acne medications Posted November 11, 2013 Thank you so much for your response. I REALLY appreciate hearing it from someone who can respond to my situation and tell me that they experienced the same thing. What is the strength of your accutane? As I said in my original post, I go back to my dermatologist in about a month and I have a feeling this is what my doctor is going to suggest. I might just do it and HOPE that my side effects are minimal. My skin is very sensitive to so many different things I've tried, but I'm ready to have clear skin. I don't remember what it feels like to leave the house without wearing makeup. Thank you and GOOD LUCK with accutane! Hey Kmacri13, I tried 2 different antibiotics before I got on Isotretinoin (Accutane). Neither worked at all. I saw maybe 10% improvement. I feel your pain. Each time I would look in the mirror, I swear my face got worse and worse. I never broke out on my forehead and around my nose, it was awful! I hated looking in the mirror and going to work. I work in a bank and deal with the public occasionally, so my self esteem bottomed out big time. However, I was just like you. Scared to death of Accutane. The side effects alone are overwhelming. I took two pregnancy tests before I got my pills and had to wait 30 days before I got to start taking them. During that 30 day time-frame, I changed my mind at least a dozen times. I have long blonde/dirty blonde hair that has taken me 3 years to get this long and losing hair is one of the side effects. My doctor said that it is very rare, though. But still, I did not want to go bald! I am 28 years old and I all of a sudden starting breaking out pretty badly. I always battled acne, but the past year has been pure hell. So I gave up and tried Accutane. Today is my 7th day taking it and (knock on wood) the only side effect I have experienced is flushing skin on my face, which has subsided. I just look like I spend a little to much time in the sun. My face has NEVER been this clear. Ever. I can go without makeup! Its a wonderful feeling, I tell you! I am taking a vitamin C supplement along with Biotin to prevent the hair situation. I drink alot of water, moisturize my face alot, and never leave the house without my Carmex. I have one in my car, next to my bed, my desk drawer, and my pocketbook. Probably somewhere else, too. I really hopes this helps you and your face clears up. Acne can ruin a person's self esteem and how we look at ourselves.