Under The Skin? in General acne discussion Posted April 28, 2006 Only treretinoids can help you, stop everything else. I was on Roaccutane because nothing else seemed to help. Got rid of them all with it, just ate my last pills and im pretty certain they will return after a while. I would like to continue with topical tretinoids, but with the oncoming Summer it might be a bad idea..Squeezing them is completely useless, it will return within 2 weeks and you will get a lot of red marks that last a long time.