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guitarman01 last won the day on February 8

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  1. different strains can have different effects, for example bifido longum bb536, is not the same as bifido longum 35624. same species, different strain. it goes genus, species, then strain. There could be genus wide effects, species wide or even certain strain effects that distinguish from other bacteria even of the same species. Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat ... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146849
  2. Im not sure where you are, but here in the states a higher dosage of bifido 35624, which has actually been reclassified as longum not infantis became available at 5 billion cfu per pill. Im taking 10 billion daily, this is still rather expensive at 60 dollars a month, but this dosage until now was not feasible with the 1 billion capsules. This 10 billion per day was the same dosage they used in the CFS study that lowered inflammatory markers. Ive also looked at this strain specif
  3. yea looks like a lot of good info @StopAccutane Ill take a listen when I have the chance.
  4. here's more Probiotic, Prebiotic, and Brain Development https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707719/ Recently, a number of studies have demonstrated the existence of a link between the emotional and cognitive centres of the brain and peripheral functions through the bi-directional interaction between the central nervous system and the enteric nervous system. The micro-organisms that inhabit the human gastrointestinal tract (GI) have been implicated in the development
  5. @StopAccutane I think intestinal permeability can play a role. I've possibly noticed this coincide with symptoms, along with gut dysmotility. HPA axis dysfunction, the eccentric nervous system regulating blood flow and gastric emptying. people talk about not getting sick anymore, (same in CFS) immune regulation, meaning what the body decides to go after, what it leaves alone or tolerates. Good bacteria vs bad bacteria, they are looking at this with parkinson's and other neurodeg
  6. Speaking of tests, I tested positive for all candida antibodies. This was a pretty cheap test from walkinlabs where you can get your own blood tests. Something this simple could be a start. A Type of dysbiosis that never corrects itself. Youd maybe be talking about something that becomes a part of you, that forms highly resistant biofilms that can only be eradicated and replaced with beneficial biofilms, from beneficial microbes. If this were true, I, along with current research doesn't qui
  7. Adding to what I just posted. Effects of Isotretinoin Treatment on Epigenetic Programming in T Cells Retinoids are essential nutrients involved in the maturation of the immune system. The majority of in vitro and in vivo studies provided evidence that retinoid treatment exhibits anti-inflammatory properties and is effective acne therapy. However, there is a controversial discussion about a causal relationship between isotretinoin treatment and the onset of inflammatory bowel disease
  8. Another way to term it would be tlr2 activation. Maybe immune tolerance, immune stimulation, immune activation, immune suppression= immune regulation. Understand long term effects on this could manifest itself in numerous ways even years down the line. This is seperate from blaming all life problems, the normal aging process, or genetics on Accutane. Unfortunately though the line will become more blurred as people get older. Some will ask themselves the question, What
  9. @Justdry Unfortunately some things might not become realized until the problems become worse. I started out with just dry skin. I think some regress, progress, or stay about the same. The Gut Microbiome as a Major Regulator of the Gut-Skin Axis Published online 2018 Jul 10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048199/ Though not yet fully explored, the mechanisms by which intestinal microbiota exert their influence on skin homeostasis appear to be related
  10. A couple observations. I think the anxiety, facial flushing is a type of gastric motility problem. You could also put this in the realm of alternating constipation/IBS This could be somewhat symptom free as well, meaning you might not be aware Ive seen the studies. Skin hypersensitivity, neurologic symptoms due to impaired gastric motility. I think the eye problems also involve the muscles around the eye. All these muscles also push blood flow or circulation, and
  11. retinoic acid metabolism, animal fat metabolism sugar/glucose metabolism wheat/gluten metabolism dairy/ milk metabolism cholesterol metabolism protein/ sulfur metabolism pick one. @VanceAstro There's another recent study very similar to that one I posted. So similar I wonder if its the same authors or not. I'll have to see if I can find it again when I get a chance. it goes on about hypothesizing Accutane's permanent effects and the problems th
  12. Everything a person eats, what they dont eat, even exercise, can affect the microbiome. This in turn might affect much more.You see ties with what I recently mentioned on here with sulfur metabolism. Gut Bacteria and Hydrogen Sulfide: The New Old Players in Circulatory System Homeostasis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273628/ Accumulating evidence suggests that gut bacteria play a role in homeostasis of the circulatory system in mammals. First, gut bacteria may
  13. Another really good study. Gut inflammation in chronic fatigue syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964729/ Chronic fatigue syndrome (CFS) is a debilitating disease characterized by unexplained disabling fatigue and a combination of accompanying symptoms the pathology of which is incompletely understood. Many CFS patients complain of gut dysfunction. In fact, patients with CFS are more likely to report a previous diagnosis of irritable bowel syndrome (IBS), a comm
  14. i've seen a few people mention this. I could relate this similar to a foot or leg falling asleep. Loss of sensation or feeling. Except for some the loss of sensation does not come back for whatever reason. I think this could be a circulatory issue at its core. This blood circulation can also be controlled by the nervous system, so this could possibly fall into autonomic nervous system function. Obviously this isnt exclusive to one body part as you said you feel it in your head as
  15. @realninja Thanks. I see we have some overlapping thoughts. I'll keep what you said in mind. On methylation. When I think of this I think of sulfur metabolism. On Sulfur, probably not thought of much, its the third most abundant mineral in the body, vital for skin and hair. Errors in sulfur metabolism, just a few quick thoughts on it. Microbial pathways in colonic sulfur metabolism and links with health and disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508