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guitarman01

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guitarman01 last won the day on December 1 2018

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  1. @Justdry Unfortunately some things might not become realized until the problems become worse. I started out with just dry skin. I think some regress, progress, or stay about the same. The Gut Microbiome as a Major Regulator of the Gut-Skin Axis Published online 2018 Jul 10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048199/ Though not yet fully explored, the mechanisms by which intestinal microbiota exert their influence on skin homeostasis appear to be related
  2. A couple observations. I think the anxiety, facial flushing is a type of gastric motility problem. You could also put this in the realm of alternating constipation/IBS This could be somewhat symptom free as well, meaning you might not be aware Ive seen the studies. Skin hypersensitivity, neurologic symptoms due to impaired gastric motility. I think the eye problems also involve the muscles around the eye. All these muscles also push blood flow or circulation, and
  3. retinoic acid metabolism, animal fat metabolism sugar/glucose metabolism wheat/gluten metabolism dairy/ milk metabolism cholesterol metabolism protein/ sulfur metabolism pick one. @VanceAstro There's another recent study very similar to that one I posted. So similar I wonder if its the same authors or not. I'll have to see if I can find it again when I get a chance. it goes on about hypothesizing Accutane's permanent effects and the problems th
  4. Everything a person eats, what they dont eat, even exercise, can affect the microbiome. This in turn might affect much more.You see ties with what I recently mentioned on here with sulfur metabolism. Gut Bacteria and Hydrogen Sulfide: The New Old Players in Circulatory System Homeostasis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273628/ Accumulating evidence suggests that gut bacteria play a role in homeostasis of the circulatory system in mammals. First, gut bacteria may
  5. Another really good study. Gut inflammation in chronic fatigue syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964729/ Chronic fatigue syndrome (CFS) is a debilitating disease characterized by unexplained disabling fatigue and a combination of accompanying symptoms the pathology of which is incompletely understood. Many CFS patients complain of gut dysfunction. In fact, patients with CFS are more likely to report a previous diagnosis of irritable bowel syndrome (IBS), a comm
  6. i've seen a few people mention this. I could relate this similar to a foot or leg falling asleep. Loss of sensation or feeling. Except for some the loss of sensation does not come back for whatever reason. I think this could be a circulatory issue at its core. This blood circulation can also be controlled by the nervous system, so this could possibly fall into autonomic nervous system function. Obviously this isnt exclusive to one body part as you said you feel it in your head as
  7. @realninja Thanks. I see we have some overlapping thoughts. I'll keep what you said in mind. On methylation. When I think of this I think of sulfur metabolism. On Sulfur, probably not thought of much, its the third most abundant mineral in the body, vital for skin and hair. Errors in sulfur metabolism, just a few quick thoughts on it. Microbial pathways in colonic sulfur metabolism and links with health and disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508
  8. sorry for spamming, but i think this is worth reposting to keep it on a current page for abit. This study was published about a half a year ago, some of these newer thoughts and research didnt exist back in the 80s or 90s. Just like technology, they are discovering more and more at a rapid pace. At least there's still plenty of current research on Accutane. switching gears for the moment, this is kind of what im looking at right now. Possibilities. https://www.cell.co
  9. Remember this study. I cant copy the image, but I want you to look at the first image. Published: 04 Jul, 2018 Severe Acne in Female Patients Treated with Isotretinoin is associated with Dysbiosis and its Consequences https://sciforschenonline.org/journals/clinical-cosmetic-dermatology/article-data/JCCD-2-131/JCCD-2-131.pdf Conclusion: In female patients, isotretinoin is associated with dysbiosis, malabsorption and dysimmunity. Isotretinoin is associated with dysb
  10. Its kind of funny scanning whats available as bifido only supplements, I come up with about 3 or 4. This is out of all the probiotics on the market. life extension, probiotic pearls (the 100 percent bifido version) and Align. They are giving babies 8 billion, a study on inflammatory markers in Cfs used 10 billion, to give an idea of dosage. Anything higher then that becomes less fessabile cost wise depending on what your trialing. Im not sure yet about prebiotics as they can be le
  11. my b12 was fairly low one time when I had it tested. I had a follow up test and it was right in the middle. Vitamin B12 564 pg/mL 211 - 946 Regarding this though, this is a probiotic species I have been looking at closely, Decreased Vitamin B12 and Folic Acid Concentrations in Acne Patients After Isotretinoin Therapy: A Controlled Study biosynthetic pathways of bifidobacteria include synthesis of Vitamin B12 and folates https://www.sciencedirect.com/science/article/pii/S
  12. Im going to repost some tests here. Association Between Oral Isotretinoin Therapy and Unmasked Latent Immuno-Mediated Diabetes http://care.diabetesjournals.org/content/32/8/e99 "the only remarkable change of lipid profile consisted in a reduction of HDL cholesterol during isotretinoin treatment" During. Thats the scariest part. Ongoing remission and ongoing symptoms could mean Accutane sides just like in the pamphlet and beyond could happen very far down the line. An
  13. So here's a real simple possibility. Ive posted this before. Acne itself could be a type of immune response or defense mechanism. So maybe you quell the immune response or suppress the over reaction. Id be looking at inflammatory and immune markers, metabolic, (hdl,ldl,cholesterol, glucose) even looking down allergic type pathways, you can see this going in many different possible directions. Isotretinoin as a Possible Environmental Trigger to Autoimmunity in Genetically Susceptible Patient
  14. I'd actually be looking at a more targeted approach as opposed to a fecal transplant. Alot of current research is looking at very specific strains. What truly is a probiotic? Different strains and species have shown to be competitive at times and not all benefit the host. So just throwing the kitchen sink at the problem (fecal transplant) and hoping for the best, to me doesn't seem the best way to look at this. I also believe most probiotics become transient and not allowed to
  15. This is what im looking at right now, especially being the fact it might play a integral role in vitamin A metabolism. Meaning if you provide a surplus or overwhelm with high dose retinoids, Bifido might become depleted. In the CFS study they used 10 billion cfu's per day. This dosage only recently became available in the states. The human gut microbiota contains a diverse bacterial species understood to exert numerous physiological functions such as protection against pathogens, bar
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