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About VanceAstro

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  1. Isotretinoin is known to cause gut dysbiosis, unfortunately no one knows how to revert it. Severe acne treated with Isotretinoin is associated with dysbiosis and its consequences: https://www.longdom.org/proceedings/severe-acne-treated-with-isotretinoin-is-associated-with-dysbiosis-and-its-consequences-18440.html
  2. Did anyone managed to fix the post-accutane malabsorbtion syndrome (particularly fat malabsorbtion)?
  3. Well, in my case prebiotics (inulin for example) and high fodmap vegetables & fruits (cauliflower, broccoli, apples etc.) make things much worse.
  4. I took 224 billion of VSL#3 and 2 billion of Bifidobacterium infantis 35624 daily for around one month. Today I decided to give another chance to Bifidobacterium infantis 35624 and I've ordered another 90 caps (1 billion each). But I'm really eager to try some antifungals.
  5. Regarding dysbiosis/candida overgrowth/pseudo-celiac disease (potentially caused by the suppression of TLR-2 by Isotretinoin), I've just finished taking a combination of VSL#3 and Bifidobacterium infantis 35624, but so far I haven't noticed any significant improvement. And since I don't know any better probiotics, I will most likely have to find a good gastroenterologist and ask him for antifungals or some anti-sibo drugs (small intestinal bacterial overgrowth is the first thing that c
  6. I do. It's called fat malabsorbtion. This was the first side-effect that I've noticed after starting low-dose accutane. Basically, the more fat I consumed the more often I had to visit the toilet. Later on I also found out that I can't tolerate/digest certain fruits (apples for example). I have never had these problems prior to taking Accutane. I think this study best explains what happened to us, but unfortunately, I have no idea how to reverse the damage. Below you can find some
  7. So now I understand why I can't digest fat/fructose/dairy/wheat after treatment with Accutane...because it can induce permanent mucosal atrophy (just like in the case of Celiac Disease?) which in turn leads to permanent dysbiosis/SIBO. Some really scary stuff, especially when you consider the fact that "No therapy is available yet".
  8. Good question. I also suffer from fat malabsorbtion post accutane (for more than 8 years now...) and I have tried every available probiotic & L-Glutamine with zero results. Studies like this one confuse me even more...(i.e. "Isotretinoin had no significant effect on the faecal microbiota"). One thing that I noticed - while checking lab tests during my treatment - was increased bilirubin level...so maybe you are right by saying that Accutane can cause (permanent?) damage to liver, gallbla
  9. I doubt it. I finished my Isotretinoin course 8 years ago and I remain in a miserable condition ever since I've swallowed the first 20 mg pill (and during most of the course I only took 10mg/daily - which is considered a very low dose). Isotretinoin can permanently damage the gastrointestinal tract of susceptible people (and you will never know if you are susceptible or not, you will find out only after you swallow the first pill - it's a pure lottery). I, for example, ended up with Crohn's
  10. I am most likely suffering from Isotretinoin-induced cholestasis. I am unable to digest fat (and fructose) ever since I swallowed first 20 mg pill (7 years ago!). Shortly after I started my low dose course I've noticed increased frequency of yellow bowel movements (particularly after consuming a high-fat meal). Liver function tests showed elevated bilirubin levels, while other liver enzymes were within the norm. I have tried probiotics, digestive enzymes, liver supplements... nothing helped.
  11. Did anyone managed to fix the digestive side effects of Isotretinoin? (i.e. loose stools, fat & fructose malabsorbtion, very loud stomach gurgling etc.) ?
  12. Hi. I saw your comment about carnitine repairing long term effecs of accutane. Does it work for your? Please answer me ... I’m worried. I use accutane 4 YEARS ago. Since May/2016 I’m suffering this effects... like dry syndrome, ear ringing and join paint. My life was ruinned. Thanks.

  13. Did anyone managed to cure post Accutane fat malabsorption (or at least got a proper diagnosis)?
  14. I was also thinking about SIBO, but I don't think that pale stools & fat malabsorbtion (and, in my case, also slightly elevated bilirubin) are the classic manifestations of SIBO. Such symptoms are usually connected with liver, galbladder or biliary tree disorder (biliary sludge?). But when Isotretinoin is concerned, you can't count anything out:
  15. I took one course of low dose (10mg) Isotretinoin and it has completely messed up my digestive system (I can't tolerate fat and fructose anymore). Symptoms started already few hours after swallowing the first capsule (very loud stomach noises - particularly at night and after lying down). Two weeks later I have noticed much brighter stools (common symptom of fat malabsorbtion). My liver enzymes were in the normal range during the whole treatment (apart from slightly elevated bilirubin). I have t