I'm getting tired of jumping through hoops at my dermatologist's office so I had my dad (who's a periodontist) write me a prescription for minocycline. The dosage reads that I ought to take 2 pills every 12 hours, each pill at 100 mg, the first day beginning with two pills taken at once. There are a total of 30 pills in the bottle with no refills. My acne isn't terrible, just incredibly persistent, and my skin is very very sensitive. I am about 5'5" and without a scale I'd guess 115 lbs. I was h