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Neutrogena On-the-Spot Acne Treatment (Old Formula)
3.4/5 - 369 reviews
5 star
76 reviews
4 star
125 reviews
3 star
89 reviews
2 star
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1 star
38 reviews

Brand: Neutrogena

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Neutrogena On-the-Spot Acne Treatment (Old Formula)


Active Ingredient:
Benzoyl Peroxide (2.5%).

Inactive Ingredients:
Water, Bentonite, Caprylic/Capric Triglyceride, Glycerin, Emulsifying Wax NF, Polysorbate 20, Glyceryl Laurate, Cetyl Dimethicone, Magnesium Aluminum Silicate, Xanthan Gum, Sodium Citrate, Disodium EDTA, Citric Acid, Methylparaben, Propylparaben.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

Neutrogena On-the-Spot Acne Treatment (Old Formula)

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Neutrogena On-the-Spot Acne Treatment, Vanishing Formula, .75 oz
updated: 09/30/2016 23:58 UTC
Neutrogena On-the-Spot Acne Treatment, Vanishing Formula, 0.75 Ounce
updated: 09/30/2016 23:58 UTC
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Neutrogena On-the-Spot Acne Treatment (Old Formula)

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Reviewed on May 19, 2014

I used this before I had purchased Dan's BP. It left my face feeling sticky. I hated the creamy consistency, didn't seem to absorb well.

OK in a pinch
Reviewed on April 19, 2014

This is the first 2.5% benzoyl peroxide I ever saw, so props for that. However, it comes in a very small .75oz. tube which means if you use it with The Regimen it becomes very costly. It is also cream based which makes it harder to apply than a gel, and also makes it prone to leaving streaks. The worst part about this product is that it turns white when you sweat which is embarrassing. It can be used in a pinch, but gel based benzoyl peroxide is far superior.

by ThisUser on 04/20/2014 14:45
How do you feel about using a 2.5% Benzoyl Peroxide pad when in a pinch? For example, if you normally do the full regimen, but get home really late one night (once a month) and use the pad, is that going to be more effective than skipping the BP application entirely? I would think so. I saw that Oxy has a new BP pad which I bought for this type of emergency situation (no comedogenic ingredients that I can see). What do you think?
Reviewed on April 17, 2014

This product works very well on acne with (Dan's R). My skin is use to Benzoyl Peroxide. However, this one is much less irritating and creamy. There is two problems I have with this product. It comes in only a small sized tube.. which if your like me you will go through fast for the 2 times daily application. WOMEN!! NOTE THIS PLEASE! if you want your makeup to look smooth with application do not use this product!! it turns white when you sweat and balls up. I noticed after using liquid makeup with my beauty blender allowing both my BP to soak in. Moisturizer and primer that it got very cakey look to my inner t zone. It took me forever to figure out what was the cause of this. I love to use this at night but like Dan said a gel based BP sounds more ideal. Im thinking about ordering the one from Acne org because of the good reviews as well as its hard to find a gel based BP that is 2.5%

Works well with Dan's Regimen
Reviewed on April 3, 2014

This cream works really well for me; it dries out my skin, of course, but all BP products do. If you use it with the Regimen like I do, it will work wonders! All you need to do is moisturize adequately and be sure to use a cleanser that won't dry out your skin. One downside, however, is that the tube is quite small, and it's expensive to buy a bunch of tubes instead of buying another bigger BP product. Also, the cream can be difficult to spread around the skin, and it sometimes leaves a white residue, which is especially noticeable when wearing foundation. For these reasons, Dan's BP might be better, but this is nevertheless a great alternative!

Worked better than expected!
Reviewed on March 2, 2014

Neutrogena on-the spot treatment worked better than I expected! I had bad acne and it was very hard to remove it. After 5 days of using this product, the prone spots were fading and healing.

Good to use if you can't buy the BP on
Reviewed on February 19, 2014

This tube is good if you can't to buy the gel from I used it my first week of being on the regimen, and I have to say that it is somewhat better than the gel on It minimized my zits a lot faster, didn't irritate my face as much, and helped me get clearer. The only problems I have with it is that it is too small, to buy 8 oz. worth is much more expensive than the gel on, and it doesn't absorb too well. I would recommend it to anyone who can't buy the gel on

Good but...
Reviewed on February 4, 2014

I started The Regimen about two weeks ago and this is what I had in hand. It does work pretty much the same as the treatment does, but this one comes in cream form. It's supposed to be "vanishing cream" but after it dries out it is still visible, particularly if you have to use a lot, as required by the Regimen. This may be a non-issue for some, but if you want to apply foundation later on, it will cause make-up to cake on and look bad. Aside from that, I experienced the same dryness and peeling that one would expect with a BP treatment, and my zits dry up faster than before I started using it, so it must be working.

Ok product
Reviewed on January 18, 2014

I started using this product over night, it cleared up my acne for a while but then it started to make my skin feel dry. I figured it was doing its job and I expected some dryness and flaking so I just used extra moisturizer. Then my mom pointed out that my skin looked almost burnt in a very unhealthy way. I was switching this product with a different benzoyl peroxide product. I'm not sure if this made a difference, but after stoping on the spot acne treatment the burnt skin went away.

by Laurenluvsurf on 09/17/2014 00:04
I have the same problem with the burnt skin how long did it take to go away
Never worked for me
Reviewed on December 26, 2013

My skin got really greasy and hard and it brought the face demons out.

Does what it says
Reviewed on December 3, 2013

It does exactly what its says it does it helps clear skin just like in the regimen. It does make your skin red and irritated so it took me about 3 weeks to get used to it. Just be patient and find a really thick moisturizer to help with the side effects. I thought it helped a lot when i used a moisturizer with sunscreen in it after this because the white cast the sunscreen has helps tone down the redness. It also works very well as a spot treatment (which is the name) because it drys up the zit over night. Good luck :)