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  1. I'm 24 and have dealt with acne scarring ever since I had really bad acne in high school and went through accutane (late 2007). I got fraxel laser treatments twice - I think the first treatment was around 2011 and they did about 3 treatments, and then I just finished the second round (went 4 times) in 2016. I am still having scars which I can easily see in indirect light. I think the second round in 2016 helped out a little bit to make my face smoother and round out the edges on my scars, but these scars are still very visible in my mind. I'm not going through any psychological issues where I dont want to be in public, its just I kind of want these all to go away and move on with my life. I'm still doing fine socially as well as with girls, but I feel like they can still definitely notice them. As you can see I can make the indirect light to show these scars, but in other lighting it doesnt look like I have any scars at all! I really just want to know what types of scars I have and what you guys think I should do about it. I'm open to anything, and id be willing to spend up to 5K if need be for any procedures. Do people think I shouldn't use lasers again? As to the scars - I think left cheek is worse because of the two scars at the top of my check which are the deepest scars that I have. I feel like the right cheek doesnt have as deep of scars. Also, on the bottom left side of my chin I have this very deep crater which is unlike any other scar on my face. It sorta just gapes deep into my skin. I think you can see it best in my very last picture. **let me know if you need me to post any more pics with better lighting to make a better read on what I have/should do, this was my first time taking pictures like this Pictures (I took two of each cheek): Right cheek: Left cheek:
  2. So I'm starting Accutane this week, and I move in to my college this weekend. I'm in a fraternity so when my dermatologist told me to stick to 3 beers a night (when I'm drinking, so like Thursday-Saturday) I became frustrated. I'm pretty concerned about this because obviously alcohol is a big part of frat life. How strictly should I follow her advice? 5-6 months of only drinking beer does not sound like a good time. All advice is welcome, thanks!
  3. Hi everyone, I've been lurking on here for a few days now and figured I would post my own issues. I'm mainly looking for advice, tips, and experiences. I started Accutane (50 mg/day) 3 days ago. I wasn't paranoid, or anxious about taking the medication until yesterday. It doesn't help that I'm a highly anxious person as it is! I'm so scared about the side effects it's crazy, but I'm SO OVER acne and how self conscious it makes me feel. 10 years of acne and literally hundreds of antibiotics, creams, gels, scrubs, vitamins, diets, and so on and no relief. This is like my last chance. But what worries me mainly are how weak, fragile and easily hurt your skin can become, and the joint pain, hair loss, headaches (already getting bad headaches since yesterday), and so on. Those who had side effects, when did they start, how long did they last, etc? I know everyone is different, but I'm just a bit paranoid. If you finished the medication do you still have lasting side effects? I've done a lot of research to know it's possible, despite my dermatologist saying it isn't over and over... pretty scary! Any tips or advice for me? I'm thinking of getting Eucerin lotion or CeraVe. Right now I have Lubriderm but I guess that isn't even for your face. Is there any vitamins that would be good? I take a multi vitamin, biotin, and b12 daily. Just tell me anything I should know! I'm definitely paranoid about these side effects I could experience, and it's stressing me out. But I also could use some advice for what products I should use. I'm hoping I don't have an initial breakout badly too, especially with starting a new job soon.
  4. I am finishing month 4 of my 6-8 clarus (canadian generic version of accutane) course. I take 40mg (up from 20 in month 2) a day and there was a little progress early on and it plateaued after that. I feel like part of this progress is from just improving my overall hygiene, and less stress. I take medication with food and on time mostly (some times it may be take a few hours late because of work and such). I get dry lips and eyes but no facial dryness or flakyness like everyone else describes. My forehead and nose still get oily to some extent. I don't know if the accutane is doing it's work or not. I was wondering if I should get a higher dosage in month 6 or if I'm doing something wrong. I'm a 20 year old male that 54 kgs and 167 cm tall. Here are some pictures, wondering how bad my acne really is? I was told by my physician that i have grade 3 acne. Thanks, any and all advice would be appreciated.
  5. I am finishing month 4 of my 6-8 clarus (canadian generic version of accutane) course. I take 40mg (up from 20 in month 2) a day and there was a little progress early on and it plateaued after that. I feel like part of this progress is from just improving my overall hygiene, and less stress. I take medication with food and on time mostly (some times it may be take a few hours late because of work and such). I get dry lips and eyes but no facial dryness or flakyness like everyone else describes. My forehead and nose still get oily to some extent. I don't know if the accutane is doing it's work or not. I was wondering if I should get a higher dosage in month 6 or if I'm doing something wrong. I'm a 20 year old male that 54 kgs and 167 cm tall. Here are some pictures, wondering how bad my acne really is? I was told by my physician that i have grade 3 acne. Thanks, any and all advice would be appreciated.
  6. Hey guys, I’m a 19 year old girl and went on a very successful Accutane course of 40mg from December 2015 -August 2016. I don’t regret it and adore my current skin, but hair loss was always the ONE THING I didn’t want to experience. I was happy to risk the other side effects, even liver damage. What I didn’t want to do, however, was trade in one aesthetic problem for another. I started experiencing telogen effluvium hair loss in June (it was then that I started shedding moderate amounts of hair with bulbs). This got a bit heavier in July, and I really began to hate washing my hair because it was traumatic to see such loss. I avoided brushing my hair but generally tried to ignore it. In August, the shedding got extremely heavy. I would shed hair everywhere I went, and I’d brush my hair and see 80 hairs in the brush. It was horrible and I prayed it was peaking and would soon stop. September/October were absolute hell (it’s the 2nd of November today). Up until September, I didn’t notice visible thinning. That’s how I coped over the summer – I was shedding like mad, but my hair still looked lovely and luscious. Half way through September, my hair started looking much thinner. When wet, it looked horrible. Every time I washed it in Sept/Oct, I would lose about 250 hairs and then literally 400 hairs for 2 days afterwards. As my oil had come back at this point, I had to wash it at least every 5 days, resulting in regular trauma. I would sit in class, feel my pony tail and just pull out 40 loose hairs every hour. So, so horrible. Now, at the beginning of November? My parting has doubled in width. It's not terrible bit it's terrifying to me. You’re probably here to see whether accutane TE gets to the point of “embarrassing thinness”. The truth is I don't know, and that's what I have tried to find out online, in vain. I guess we will see what my hair is like in March! I want to stress that I don’t have “thin” hair. I am lucky that I had a lot of fine hair to start with, so I have decent scalp coverage still and a normal looking ponytail. You would see me and think I had nice hair, but I have lost 1/3 of my hair at least. And I’m still shedding heavily. I think the shedding is now less heavy than it has been these past two months, but who knows. REGROWTH: I checked my scalp today and am delighted to say that I have lots of 1-3inch hairs dotted around the place. They seem very fine and will obviously take months and months to grow out to the length of my others, but they will offer scalp coverage. I DON’T seem to be losing these short hairs, so (fingers crossed) hopefully I don’t have chronic TE. I am terrified to say anything now in case my condition worsens but maybe, just maybe, these past 4 months have been the worst of my TE and the shedding will slowly stop now over a few months. I will add pics soon and document this entire process... I promise I won't disappear. There is nowhere near enough information on Accutane TE out there, especially not posts from females who absolutely adored their former hair. It all seems to be guys questioning whether they have TE or genetic balding. I can't believe that my hair still looks like "nice hair" given I've shed so terribly for months. What I will say is that I am never, ever risking hair loss again. This will put me off ever meddling with the contraceptive pill, antidepressants, etc. Might sound extreme, but everything’s relative, and this is one thing that I was never prepared to deal with, and will hopefully never deal with again.
  7. Hello, I am a 19 year old female. On July 21st 2017, I was put on Spiro, at 100 MG a day. I take Nuva Ring Birth Control with it. I have struggled with moderate to severe acne since age twelve. A very brief history on my acne, I tried every OTC product that exists and three step system. I tried Bactum antibiotic and a topical prescription in High School. I had persistent and moderate acne for four or five years. It really destroyed my social life, self esteem, and put me into a deep depression for a long time. I was bullied a lot for my acne as well. I was put on Accutane in my Sophmore year or Junior year, I don't remember. It cleared me of acne completely, something I didn't even remember the feeling of. I never saw myself with clear skin since I was a child. It only took 1-2 months for it to clear. I was on it for I think 4-5 months. I had side affects of IBS, back pain, super dry skin, and very chapped lips. The cons didn't bother me compared to the pros. It kept me clear for 3 years. I am now entering my second year of College in a week. I switched my Birth Control Method to the Nuva Ring about a year ago, with no acne problems. I was originally on Ortho Tri Cyclen. I was just sick of taking pills. I went a year or two feeling confident with zero makeup in public and strangers would tell me they would've never known I struggled with acne for years. I liked going natural. In May 2017,three months before today, I thought why not quit taking my Nuva Ring too. I thought I grew out of acne and was cured from Accutane. I got my first apartment in April with my boyfriend who never even saw me with acne for the three years we have been dating. Two months later, It was July and my face exploded in acne like I haven't seen for years. It was all over my forehead like Middle School. Looking back, since March of 2017, I was noticing more frequent acne, It just never got bad enough to bother me till Summer 2017. It spread badly on my cheeks as well. I also have tons of white heads. I was so devastated and thought my boyfriend would leave me and be disgusted by me. I usually wouldn't even wear makeup around him. Acne scars didn't bother me. I have been a hermit, crying, rarely leaving my apartment. I feel so insecure in public without makeup. I have come to hating applying foundation after years of needing it. I feel depressed putting on makeup and seeing the acne still. I can't believe it came back so heavily. I started taking the Nuva Ring again in July when it got so bad. A few days later, I was prescribed what I stated at the beginning, 100 MG of Spiro a day. I was also prescribed Retin A Cream, 0.025. I was told to continue my Clindamyacin Gel as a spot treatment, which worked amazing after Accutane with small breakouts. It has been a few days more than 3 weeks on Spiro. I haven't seen much progress. My forehead acne is almost gone from the Clindamyacin gel. I still have bad acne on my cheeks, temples, and white heads on my chin. I personally think it's almost gotten worse since I started, on my cheeks. The Retin A is awful and I don't want to use it, it is so drying and it worsened my cheeks. I just wash with Cera Ve cleanser, Clindamyacin gel, and Burts Bees moisturizer. I feel pretty sad and anti social. I decided on taking all online classes for my first semester of College in a week. I truly don't want to be seen in class this way. It's sucks struggling for four years, being clear for about three, just for it to explode nearly as badly again. I'm trying to stay positive because it's not a quick fix. It's so hard though. I'll be back when I hit the one month mark, and probably post weekly or bi weekly my journey from there. I hope this goes well and people will support me or I can help someone else.
  8. My forehead got a somewhat different texture to it after maybe 3 months on isotretinoin, nothing too major, and now indented lines keep appearing on my face. I'm not picking at my face, and don't have any acne. Anyone else had this with isotretinoin? What is this and can it be fixed? I've read plenty on tretinoin products like Retin-A causing this.
  9. Hi, thanks for calling by! I've never written a review about a medication journey before but as roaccutane is still a taboo subject for some I thought I'd share my journey. Ok so my weight at day 1 was 56kg im 5"1 1/2, that half inch makes all the difference lol so I'm a female 34 years old now and my acne started when I was 21 years old and pregnant with my first child. Before then I'd had perfect skin not even any pimples or spots through school. at first I tried to live with my acne which was mainly black heads with spots that would surface as red lumps and be very sore to the touch and surrounding areas would be sore too. Squeezing would sometimes help clear them up but then sometimes squeezing would make them bigger and then they would become cuts that would take an age to heal on my face and chest. I visited my gp who put me on antibiotics for 6 months. This only slightly helped. I was referred to a dermatologist 10 years ago who tried me on antibiotics again then a gel for my face then a cream for my face but all they seemed to do was burn my skin. I changed my contraceptive pill, this didn't help either, I tried face washes, no face washes, microdermabrasion no success, acid peels no success with this either, tried cutting all my hair off as some would suggest it was oil from my hair (shampoo oils etc) this didn't work either as the spots remained and by now started to appear on my back. My spots would be worse when I bathed in the sea and exposed myself to sun but would really help clearing them up for a short time. Once back from holiday they would rear their ugly head again. I also suffer with books around my groin area too. I also have chronic greasy hair with dandruff and make up would slide off my face within an hour. I'm painting such a pretty picture of myself here! Lol So that's the back story. after 10 years of begging I finally got another referral to the derm who after looking at me instantly said roaccutane was my best chance. Cystic acne. I went through all the lectures on pregnancy etc which are very important lectures to listen to due to the side effects. I changed my pill to the combination pill as I was on the mini pill and I received my first months supply. I was on a low dose of 20mg. For the first few weeks I felt quite tired and had vivid dreams. At this point I didn't exercise but was active doing DIY, mowing lawns etc. My skin began to go red and I didn't apply moisturiser as I thought the point was to dry your skin out? But turns out moisturising was key to keeping the process flowing. Was prescribed dermol 500, dermabase and aveeno cream. Work fantastic but found dermol was by far the best facial moisturiser for me and intensive care cocobutter for body. All applied after a bath/shower. My lips started feeling tight so started trying out different lip balms. Go to home bargains far cheaper there. Just because it's expensive doesn't mean it will work for you. Its trial and error. Always carry something even If it's a pot of Vaseline. i Also found my lady bits became sore/dry/itchy and had a couple of episodes of thrush. Try hydrocortisone cream externally failing that visit your gp for further advice. -Month 2 my tabs were raised to 25mg and the tiredness continued but the dreams eased off. this is when my chest spots went crazy and I had all white heads appear overnight (ok might have been a couple of days) from the start I applied factor 50 sun cream to my face and wore a hat as often as possible. My lips began to feel tight and peeling I found Nivea the best lip balm. I stopped washing my skin with exfoliation gloves as the burn when you moisturise was very real! My greasy hair improved! My dandruff improved but Had scabs on my scalp so was prescribed dermax shampoo. This is also the time my heels began to hurt, when I walked at first or woke in the morning they would be tender and stiff but would ease the more I walked. But the tenderness remained. My hips began to stiffen the longer I stayed in a position such as sitting on the sofa so id have to get up and walk around to loosen up. month 2 I noticed my clothes getting tighter on me. My appetite never disappeared. But I eat clean to a degree. -month 3 my meds were upped to 40mg my joints started to stiffen quite a lot and I had to pace myself. I made the mistake of visiting a theme park with my children and by the afternoon I was in agony with the joint pain and moved at a snails pace. Due to the fatigue of the increase in meds I developed low mood and started finding myself short tempered and crying over silly things. Make sure please! That you have someone on speed dial who knows your on this medication to call when or if you have these moments to speak to even if it's just to moan about things which others may find silly. When your on these tablets the emotions are very real to you and can affect you more at this time than it might any other time or to someone else. It does not make you a loser or a weak person. It's the chemicals talking! i spoke to my mother and best friend when i needed to and even came off the Meds for a couple of days to clear my head at my next appointment I spoke to my derm nurse to tell her what happened and what I did to ease the issue. Always be open about how you feel. During this month all the black heads and spots opened on my face and literally with a hair pin slipped across my face they all popped. I had large pores for a day but using an ice pack they shrunk. Yay! Massive improvement on my back and chest! -month 4 meds upped to 55mg the heel issue remained and gets worse depending on what I do. I started light 10 minute exercises each night. My acne is clearing up amazingly and no new black heads or spots but I have gained 5 kg so I've been booked thyroid tests and derm nurse agreed it needed investigating. -month 5 meds upped to 60mg due to the weight gain and an extra 4 weeks added to my treatment plan. So my joints hurt a lot! My ribs on my chest feel like they need to stretch and my back is stiff! I've had my final 4 weeks today and I have to say its happy day! My spots have dramatically improved if anything disappeared. Roaccutane is a tough journey but for me it's been worth the hard journey! If you have any questions no matter how peculiar to do with taking roaccutane feel free to ask! After my chest cleared up
  10. I am 42 and live in the UK. I have suffered with acne on and off since puberty. When I was young it was mostly on my chin, back and chest. It was mostly kept under control (but not clear) with Birth Control, and when I had my children (17 months apart) My skin was at it's best until my second child was around 3 and then it started getting bad again. I tried different pills again and over the years have tried loads of OTC treatments and nothing has cleared it. As I am of a certain age, my GP suggested I use the coil (Mirena) I was a little concerned that it may affect my acne, but was assured no. 6 months after having it fitted, My back started breaking out. I went to the GP and was given 50mg a day of doxy. Took this for 2 months and no improvement at all. I stopped for a while (i get thrush with antibiotics). I thought the acne may be a passing side effect of Mirena, but now 15 months after it, I still have terrible skin on my back (face is fine!) . I have recently tried differin and I am now on 100mg of doxy ( month 2and no improvement) as I am so pissed off with having huge cysty painful spots on my back and greasy skin. I am back to the doctors next week and hope to try Accutane in order to clear my skin once and for all.
  11. Hi, I was on accutane for like 5 months and I've been off for a while now. After being on holiday I have got a few spots. Is my acne coming back?! Please see photos and tell me what you think.
  12. I need opinions. I will give some backstory to aid your response to me. Im a 17 yo male who has struggled with bad acne for about a year and a half and for the first 5 or 6 months I had it pretty under control using OTC products, but a year ago I had a horrible breakout so I went to the derm who prescribed epiduo paired with the antibiotic minocycline (full regimen was epiduo, mino, cerave foaming cleanser, cerave am and pm moisturizers) that worked somewhat. i say somewhat because although it did clear up most of my acne it made my face extremely red and irritated (regardless of frequency of medication). although when my antibiotic ran out, my skin started to break out again. So my face at the time was red and broken out... it sucked. thus, i decided to screw this and give my skin month break on something called the caveman regimen. It did calm the redness but like you would guess the acne did not subside. so i went back on epiduo and have been on it for the past 2 and half months with little to no improvement. Red face has sustained regardless of the attempts to stop it. I went my pediatrician other day and he wants to put me back on my minocyckine.... but i know darn well to a.) taking a bunch of antibiotics is bad for immune system and b.) my acne will return right after prescription is up.. i feel out of options... i want to just take Accutane and take the bull by the horns and just push thru the side effects. Mom thinks it will make me depressed and suicidal but i am known for being a happy person so it will be easy to tell if Accutane screws up my personality. Only thing screwing with my upbeat spirit is a face full of acne and scars. Thank you for reading and any response helps. cheers
  13. I'm a mom of a son on Accutane. Did any other boys on this site grow after taking Accutane?
  14. Hello! So, this is my accutane log. Seeing others logs and activity on this forum has really helped me in the past so I wanted to give back myself. I have dealt with mild acne for the past three or for years (as one might expect in adolescence) but in the past six months it has become far more severe and cystic and painful. I have tried all sorts of OTC medication, diet/lifestyle changes, supplements, doxycycline, perscription BP/Clindamycin/Retin-A/Sulfacetamide Sodium Sulfur, and so on. So, I finally went for accutane. I just got my first doses five days ago, so I will start my log now. I am on 20mg/day (the derm who saw me wanted to put me on 40 but the doctor overseeing her wasn't comfortable with it because she has apparently seen a teenage boy before have some severe reaction to accutane- something that is obviously a risk and pretty anecdotal but I won't complain as they want what's best for me). It was pretty emotionally taxing for me last year, as I can tend to be very self-conscious and anxious and I certainly didn't have the best year, for a lot of reasons (my acne included), but things have been getting better for me. I've been changing my thought patterns, taking more care of myself, finding happiness where I can, and trying to put my acne in perspective (I could really have things so so much worse. Of all the medical conditions I could have, mildly painful and very temporary acne is a pretty good deal). So, things look uphill, for my skin and my life. I've been doing my best at least, and will continue to do so, with faith that things will get better eventually. Day 5 No positive effects yet, of course, but the side effects haven't been too bad. I've been moisturizing and using a sensitive cleanser (acure brand, from whole foods). My lips have gotten somewhat chapped and I've felt abnormally tired, but that might just be from returning to school. Slightly worried about the initial breakout (or as I like to refer to it, my final breakout-- reframing thoughts can be very helpful, though hard), but I'm really happy to be on isotretonin.
  15. Hello Everyone. Won't keep this too formal, but like many of you I tried Accutane, had a few minor side-effects while i was on it, like dry lips and skin, blood noses, dry eyes, soreness after sport, etc. Then when I discontinued Accutane, some of these effects left, but were replaced with other far more insidious side effects. In no particular order these included: -Erectile Dysfunction -Depression -Fatigue -Joint Pain and more injuries -Low Testosterone These are just the core ones. If you have these, it goes on to affect every other aspect of your life, like you become less social, and feel anxiety in social situations. It also means you no longer enjoy things you used to enjoy doing, like sports, especially seeing you’re feeling sore from it and can’t seem to gain strength anyway due to low T, or see the point in studying to do well in University because you don’t know what you want to do anymore, and struggle to picture a future where you are happy and fulfilled. You don’t want to get into a relationship and you don’t feel like you deserve one, especially because you don’t know whether you could physically perform in one, etc, etc. The fact that you don’t see an end in sight to these maladies is what makes the situation seem more hopeless, more despairing, and it is why many people commit suicide, especially in a society that insists in “all in your head” or ”you’re imagining it” “X, Y and Z had it as well and they are fine, so just get over it”. Because on the outside you look the same, people disregard it, and it is only because of the people that lost hope and ended it the only way they knew how that this issue has been acknowledged by the world, but it is still far from accepted. Anyway, luckily a lot of this bullshit for many of you should be over soon (approx 3-6 months) I have come to the conclusion that the long term side effects of Accutane is due to brain damage. The downside to this conclusion is that brain damage can’t be cured. The upside is that the difference between a poorly managed TBI (Traumatic Brain Injury), and a well managed TBI are like black and white, and if managed well you will be VERY close to 100%, but poorly managed and you will feel… maybe very similar to how you feel now. These are the symptoms of a TBI Fatigue or lethargy Irritability Depression Anxiety Difficulty falling asleep Feeling “slowed down” Feeling “in a fog” or “dazed” Difficulty concentrating Difficulty remembering becoming fatigued easily; disordered sleep; Headache; Loss of libido, erectile dysfunction; vertigo or dizziness; irritability or aggression on little or no provocation; anxiety, depression, or affective instability; changes in personality (eg, social or sexual inappropriateness); or apathy or lack of spontaneity. If these sound familiar, that not a bad thing. If you found out you are short sighted and needed to wear glasses, then it means now you can wear glasses, so you no longer need to suffer the symptoms of your blindness. Same thing here. You are currently dealing with the symptoms the best you can. However, now knowing what the actual issue is you can treat it the way science has shown it should be treated. The best measurable way to recover from a TBI is to improve neuroplasticity. This has been shown in many other animals as well as humans, and is now becoming a prominent way to treat many mental illnesses. The most conventional way is through “Mindfulness Meditation”, which is a form of meditation where you get comfortable and try to think of nothing for 10-30 minutes a day. This has been shown to promote Neurogenesis/Neuroplasticity1 and this has been shown to help people with suicidality, PTSD, anxiety, addiction and depression, as well as chronic pain, insomnia, and hypertension. The way I’m treating myself is through the nutrition approach. It has been shown that creatine, fish oil, (unheated) extra virgin olive oil, vitamin d, zinc, magnesium, glutamine, taurine all also promote neuroplasticity. The Ketogenic Diet also helps promote Neuroplasticity, and many people who go on that diet who struggle with libido problems and are on antidepressants recover over the months and years they are on that diet. I have been doing these things for the last 5 months, and ahve noticed a great improvement in both my mental and physical health. I'm in a bit of a rush but wanted to get all this out there, so be forgiving of any and all poor formatting. Also challenge this and use what I've found to build up your own theories, and if you agree feel free to find other things we could be doing to promote neuroplasticity and improve our recoveries! Best of luck everyone 1(when looking up your own research on the topic these terms are virtually interchangeable, the ways to measure it are changes in brain metabolism and hippocampul growth) Interesting studies + exerts "Beneficial changes in the brain energy profile have been observed in subjects who are on a ketogenic diet (28). This is a significant observation because cerebral hypometabolism is a characteristic feature of those who suffer from depression or mania" Exert from a study on meditation (Decreased stress and hypertension have been related to decreased autonomic arousal or reactivity,95–97 a possible means, along with positive emotions, reduced oxidative damage,98,99 and enhanced immune functioning,100 by which meditation may preserve cognition101 and reduce age-related allostatic stress and neuronal loss, thereby promoting brain longevity, plasticity, and learning) Nutritional treatment for acute and chronic traumatic brain injury patients. "omega 3 fats, vitamin D, N-Acetylcysteine, branched chain amino acids, zinc, alpha-lipoic acid, magnesium, taurine, coenzyme Q10, and many phytonutrients" Mindfulness Meditation can stimulate hippocampal brain cell growth. A smaller hippocampus is correlated with a poorer recovery from TBIs, in the case of war veterans suffering PTSD at least. Study supporting Creatine consumption as one of the top supplements for recovering from a TBI, and this one supports Taurine use as well. Sources (For my mindblowing hypothesis) Functional brain imaging alterations in acne patients treated with isotretinoin. Traumatic brain injury: a disease process, not an event. Ketogenic Diet research article (contains research on how keto diet resets brain metabolism after TBI and how it is neuroprotective) Will add more stuff to OP over time, and reformat it as well
  16. I took oratane back in OCT 7 2016 up until JULY 7 2017, so for 9 months at 40mg/day. Before that I tried everything OTC from drugstore to highend, and prescriptions ever since I was 13 such as clindatech, epiduo, duac gel and 4 rounds of antibiotic minomycin. I also went vegan for 2 years, to improve my skin, however that was useless. I’m 16 yrs old and female. BACKSTORY - (YOU DON'T HAVE TO READ THIS) This was when i was 13/14/15 years old - Before going on oratane, I remember previously studying and having to face the excruciating pain of pimples and the oiliness that just exacerbated the issue. My motivation and self esteem was lowered significantly because I was only one of the few kids who had to suffer. I was one of the only ones who had to not only stress about assignments/homework or school academic in general, but my skin on top of it too. I also remember the big container of glycolic pads I had to take with me overseas when i went to europe (which in total took 24 hrs flight time). The main thing about this trip is I vividly remember how anxious i was explaining to security before boarding at every country i stopped at, that I used them to wipe my face down every 2 hours. No one understood and the security were confused, they probably never experienced anything with their skin and I would think to myself, Why me? I also remember when stopping in Dubai I needed to urgently wash my face privately and in peace because i get super oily within 2 hours, and if i washed my face properly i could be at ease for another 3 hours in flight. Anyways, I was eager to wash my face privately in a room, so I went to occupy the babies bathroom for a while, and all of a sudden i heard the door being banged not even knocked, I was so terrified so i didn’t even get to wash my face, I went out to the ladies bathroom and i asked my mum if it was her knocking but it was another lady, that wanted to change her babies nappies and instead had to do it on the bare floor because the babies bathroom was busy due to me in it because of my skin. I remember before I had exams in school instead of using the extra time to study, i would have to go wash my face in the bathroom, to give me refreshment and get rid of all my oils, especially before science practical exams because we wore goggles. And I remember when I would go to the bathroom at school and wash my face and the teacher would always check on me/question me to see where I was because I took quite a long while. My younger and older relatives would question and commentate about my skin. Friends would make me feel shittier when we discussed our skin concerns. It became apparent that everyone seemed to hate me because of my skin. I always tried to stay positive but no matter what my skin wasn’t improving. I thought very low of myself due to my skin, so i purposely isolated myself and became lonely. The thought of my terrible oily and acne prone skin was the first thing that always came to mind. The very very oily skin and acne made my life tougher and more stressful than it was supposed to be. It lowered my self-esteem and confidence dramatically and made my day-to-day life harder. On a daily basis my excessively oily skin and acne piled up with other mental/social health problems, was hard to deal with. I never went out nor socialised with anyone, i would stay at home 24/7, i lost all my friends, i stopped going to school, going to relatives and going out entirely. In general I had lost nearly 4 years of my youth due to being dominated by acne and oily skin. I remember feeling suicidal at times. And Yeah, those are just a few of many stories which don’t seem bad to some but in my opinion were some shit skin experiences that just exacerbated the already poor condition of my social/mental health. MY QUESTION - PLEASE HELP ME Anyhow, back on track, I have had a great accutane experience, it makes life so so so so much easier, stress-free. I am finally able to look myself in the mirror for once, i am also confident enough to look people right in the eye, submerge my cheeks fully under the shower head with ease and no pain, wake up in the morning and not be in a negative mood because of my very oily skin, and for the first time in many years lay my face on my pillow thus having spectacular nights sleep. And just to sum my accutane journey all up, I never have to feel shitty about myself no more, I am full of hope and confidence, pimples cleared and only left with cheek hyper pigmentation and redness. I am starting to improve the state of my health gradually to this day, one concern at a time. HOWEVER that feeling of hope/confidence/being comfortable was whilst I was on accutane having great skin days, no pain, no oil, etc is utterly gone, now that I have been off accutane for nearly two months. I feel like now I am back to where I just started, with the excessively oily skin issue. I am also very paranoid and anxious because it is only post 1-2 months of my first course of accutane and I already am getting very oily around my t-zone especially after taking a nap or waking up in the morning and throughout the day I produce a greasy sticky film on top of my skin which bugs me a lot because oily skin can lead to blackheads, clogged pores, more acne and in general congested skin, i am already seeing a few very tiny/minor spots (2-3). I want to go back to the accutane normal/dry skin fantasy that I was living, and not have to deal with vulnerable, high-maintenance, troublesome, and dominating oily skin. Accutane made my life much more easier, and I was only beginning to get somewhere in life and had begun to improve but now I am basically back where I had started with excessively oily skin. I have been vegan for 2 years and that did not help oily skin, my diet consists of an abundance of fresh fruits/nuts/veggies/fish, I consume a healthy diet so that is not the issue. I exercise regularly, but recently haven’t because I am depressed, alienated and overthinking what will happen to my skin and life now that I’m beginning to get oily. My skincare is very simple cleanse, exfoliate, and moisturise. I am thinking that the oiliness is genetic or hormonal. I have heard and researched of low-dosage long-term accutane, which could help reduce sebum production and congestion, but do you think my dermatologist will allow me to go on accutane again after 2 months? I just really hope she doesn’t give me any bullsh*t creams/gels that are a waste of time, because I want to enjoy the Australian summer and Christmas time of the year. I told my mum to book an appointment with my derm, which i will probably be seeing in approx 4 weeks time. Previously my school told my dermatologist that I am “depressed" but the thing is that it is not accutane that is making me feel this way, IF ANYTHING IT MAKES ME HOPEFUL BECAUSE I SEE AND FEEL GREAT RESULTS, and I need her to know that i have always had underlying depression ever since and that it has nothing to do with her nor the medication? Because I really want to go back on accutane to control my sebum production. When I visited at the beginning of July at the end of my accutane course checkup this was when my skin was in great condition and heard the “depressed” news her response was the cliche “just enjoy your life, you’re young”, i just nodded my head and smiled. It’s been 2 months post-accutane, do you think there is a good chance that she’ll put me on a 2nd course accutane on a lower dosage to control sebum production or is she going to give me another useless cream? I’m scared there is a chance she will disagree and won’t put me on it however I will mention it to her. I really want to go on it, accutane is a miraculous drug. Its nearly Christmas/spring/summer and i just want to have a good one for the first time in a long while, actually i just want to finally be at peace with myself and genuinely be happy. What has your accutane experience been like and is there another way to combat oil production besides accutane?
  17. Currently prescribed 60mg of Accutane a day & birth control for hormonal cystic acne. Cardio while on Accutane is causing me to breakout? I've been including more exercise in my lifestyle lately but have been noticing that I have strange breakouts on my face and one instance on my neck and scalp. I never breakout in either of those places besides my face, so I'm not sure what's going on? I have never broken out within 24 hours of working out, summer or winter sport, even with chronic hormonal acne (1+ cystic spots on cheeks/jawline) and no prescription. It has only occurred this month after a semi-long break in fear of joint pain during winter sport - during that time I only experienced a rash on my hands from harsh temperature. At first I thought I was suddenly experiencing cysts again but the breakout seemingly looks like milder surface acne. (But quite pigmented.) After just the third day I managed to have six spots on my cheeks! I use my own treadmill and complete other at home exercises. POST WORKOUT: I shower within 10 minutes with cool water and use an exfoliator. 1) Is this "healthy lifestyle" breakout experienced by anyone else? 2) Has anyone figured out the cause of cardio induced breakouts? 3) If you have had a similar experience - did it stop?
  18. Hi all! I'm a 6'2'' 158lb 18 yr old male who is off to college in a week! I've suffered from mild acne since I was 16, and when it got moderate-severe I went on minocycline (100mg once a day) for 8 months WITH tretinoin 5% for topical at night or scarring. It worked...until the antibiotics wore off this past month makin my breakouts worse and worse! it may bepossible that I need to find new treatment. are here any recommendations out there??? I don't want to jump to accutane especially because I'm going to college and drinking is a big part of the culture, but I don't know what else to try. I have an appointment with my derm next week before I leave...hopefully she has something that will clear me up soon thanks all!
  19. Pre-Accutane Update

    Hello, My name is Carly and I am a 21 year old female and I am about to begin my first course of Accutane. I will begin by giving a brief description of my acne journey up until this point. I have struggled with cystic acne since the age of 12. From the ages of 12-15 I tried EVERY over the counter acne medication that I could get my hands on but nothing seemed to help. In fact my acne progressively became worse as I approached my later teen years. At the age of 15, my acne ( It was only on my face at this point) became so severe that my mom decided to make me an appointment with a dermatologist. I was prescribed Tazorac, Aczone, and doxy. That combination cleared my face up beautifully and I eventually went off of the Aczone and doxy but stayed on the Tazorac. At the age of 18, my skin was pretty clear until one day when my back and chest broke out like crazy. It had never done this before so I made an appointment to go back the the dermatologist to have it looked at. I was offered Accutane at that time, but I declined because I wanted to try alternative treatments before I jumped right in. I was prescribed more antibiotics and creams and nothing has worked to clear up my back. My face also began to get more breakouts even though I continued using my Tazorac. Last month, I had a follow up appointment at my dermatologist and he suggested Accutane for my case. Since I have exhausted almost every option, I decided to just go for it and that is when I started "the process." I got my educational materials and was instructed to have contraception counseling before I could have my first pregnancy test and be registered into Ipledge. I went to contraception counseling and selected my two forms of birth control then I went back to the dermatologist for my pregnancy test and to sign all of the paperwork to be registered into the Ipledge system. After that, I waited the 30 day wait period required for Ipledge and then got my blood work done and had my second appointment. Right now, I am just waiting for my blood results to be reviewed so they can send the prescription in (which should be tomorrow)! I am excited and a little nervous to start! If you have any questions or suggestions leave them in the comments!
  20. Week 3 - Isotretinoin

    I’ve just completed my third week on 30mg of isotretinoin/roaccutane. Still no major breakouts on my face so I’m assuming I must just be able to tolerate this dose? My one month check up at the dermatologist is only a week away and I’m still feeling super positive! Although my face is clearing up, my back still needs a lot of work. I wish i could physically take a photo but my t-rex arms won't allow it. Day 15 Thursday 3rd August Same old, same old. By lunchtime my face was starting to peel around the middle of my face and nose. I’ve switched my foundation for a CC cream which is more hydrating and it seems to be helping. Once I reapplied it, my face didn’t look that bad at all. Lips are still very dry, I find that the more I speak, the more I have to apply lip balm. I also noticed that I started to develop a lump on my chin and I also have two quite large, painful spots on my back, and one small but very red one on my chest. Day 16 Friday 4th August Today I started to feel quite flushed, like I’m entering early menopause (I’m not). I’ve found that whenever I start to experience weird symptoms like this, that if I google it followed by “roaccutane” that I usually find threads of other people going through the same thing. This was one of those cases! Although my dandruff is still bad you can’t really tell if I wear my hair down. On the bright side – day 4 without washing my hair and no dry shampoo needed. I think this is going to be my favourite part. The lump on my chin also grew a friend, directly underneath it. Although I’m calling them lumps, they’re no way near the size of the ones I’d normally get and they go so much quicker. Day 17 Saturday 5th August The dryness continues! I spent the day constantly moisturising and although I didn’t need to wash my hair because it still looked fine, I washed it anyway because I was starting to feel a bit gross. I went out for drinks (coffees and lime sodas) with some friends tonight and did my special night out face prep which so far, hasn’t failed me yet. Cleanse -> Gentle exfoliator -> Moisture Mask -> Gentle cream cleanser (to take off excess of mask) -> Spring water ­-> Moisturise -> Make up My face looked completely normal! My lips were feeling really tight though, and I had to reapply lip balm pretty much every 5 minutes throughout the night. I know everyone has completely different experiences, and I’ve been incredibly lucky not to have had a monster break out yet. Day 18 Sunday 6th August The two lumps on my chin had turned into white heads! I popped them. Still not sorry. This is also really embarrassing, but I’ve started to notice that my face has become quite… hairy… only light hairs, I’m not talking full grown beard, but around my chin and my cheeks/sideburn area(?), what used to be really short fair hair that I never would have noticed is becoming less and less subtle. I can’t not see it when I look in the mirror. Has anyone else experienced this? I don’t know if it’s the pill that I’m on or the roaccutane but I’m definitely bringing this up with my dermatologist at my next appointment. I think I might stop taking this pill in the meantime and ask my GP to try another one. I’m single and I’m sober so I’m not at risk of becoming pregnant. Even so, surely having a beard will be an effective enough method of contraception. Sigh. Day 19 Monday 7th August I went to see my grandparents after work; my grandma said “oh you look great! You just have one spot there on your forehead. Oh and one there on your chin. Oh and another couple on your chest. And some – no. quite a bit of dandruff!” Day 20 Tuesday 8th August I had dry eyes pre-roaccutane anyway – but today I’ve found myself reaching for my eyedrops a lot more. My eyes were extremely blood shot again and felt so tired, but as soon as I’d used the drops they felt and looked a million times better. I’m trying to drink less coffee and more water to see if this helps but I’ve never been that good at making myself drink water. Day 21 Wednesday 9th August Still haven’t washed my hair since Saturday which is incredible for me – normally I’m lucky to get two days out of it without having to reach for the dry shampoo. I’m definitely enjoying this side effect the most although the dandruff is not as fun, but that’s only really bad in the evenings. I can’t use a hair dryer as this makes my scalp dryer. I woke up late today and didn’t have time to cleanse properly and it definitely shows. It’s the driest my face has looked over the past three weeks but also the clearest. I’ve started to develop little tiny spots on my forehead too (not the one over my eyebrow – that’s a scar from a recent car accident) and as mentioned previously, I don’t normally get them there. Here are some visuals- the make-up has been on my face since 7am though, it’s now 10:30pm: My lips are probably the most chapped they’ve been so far today. It’s nothing I can’t handle though! Products that I’ve used this week Cleanser - Liz Earle Cleanse and Polish Cleanser – Avene Extremely Gentle Cleanser Spring Water - Avene Thermal Water Spray Moisturiser – Avene Hydrance Optimale Light Gentle exfoliator- BIODERMA Hydrabio Exfoliating Gel Moisturiser - La Roche Posay Effaclar H moisturiser Moisturising Face Mask - BIODERMA Hydrabio Masque Moisturising Mask Lips - Elizabeth Arden 8 hour cream and Nivea Essential Care lip balm Body – Aveeno Daily Moisturising After Shower Mist and Sanex Dermo Sensitive Skin Shower Cream
  21. Conducting Accutane Survey Hi All, I'm considering talking to a lawyer about Accutane. Scientific studies on its effects seem to go both ways and the water is certainly muddy. Quite possibly it's not the science which is skewed but the hand of money from which the science is funded. I would like to know the true volume of people affected negatively by this drug. Perhaps there are some who aren't aware; perhaps there are some who are afraid to speak up; perhaps there are some who are not sure what to do. What's interesting is that a lot more adverse cases have been reported through the FDA in recent years. In fact the first twenty years saw 23,000 reports (1982-2002); the following eleven years saw 103,340 (2004-2015). Roughly a fivefold difference in half the amount of time. Coincidently by early 2000s household internet had become commonplace. Perhaps online medical/acne/depression forums became a way for sufferers to realise that there were others out there like them. I myself have always been pro-medicine, pro-science - generally conservative with my views in taking advice. It was only when I ran out of answers that I too came across similar complaints on the internet. A plethora of people complaining of the exact same symptoms as me. It is a very powerful thing when you can start to corroborate all of the separated pieces of evidence out there. In the first twenty years of the drug this would not have been possible, pre-internet. Perhaps Roche knew that. My feeling is that the product statistics are very incorrect and the list of side effects has some significant omissions. I've created a survey to initiate some of this information gathering. Please if you have been effected consider assisting with this. I would like to assemble the pieces of the puzzle. Note the survey is anonymous but if you would like to leave a form of contact at the end of the survey this may help shall further progress be achieved. Also if you don't mind have a think if you know anyone who might be a useful resource in such a process i.e. doctor, lawyer, politician, journalist, researcher, people in high places, etc. I have created the survey here, Thank you for your time, MT
  22. Most recent pic (Feb 06, 2014): Still posting and updating at least once every week. I'd like to stay anon for the most part but I felt like I had to post some pictures to show my authenticity. However, if you do recognize me, please keep this private as that is my wish. Thank you! My log is a little late, but better late than never! On May 22, 2013, I began an ultra low dose Accutane experiment supervised by my derm. A bit about myself before I dive in. I am a 25 year old Korean male. I am 6 feet tall and weigh about 130 pounds. I was born in Seoul, Korea but I moved to San Francisco when I was 6. I am currently in Korea and attending school. Now, the important details about my skin: I had a lot of acne growing up, especially when I hit puberty. Pretty sure it was hormonal back then since my acne improved as I hit my twenties. However, my face has been a constant oil slick and I had moderate persistent acne. I tried Dan's BP, SA, chemical peels, supplements of all kinds, facials, etc. For all the work and money I put into my skin, none of the products ever cleared me, and if they did it was temporary. My acne just did not go away and my face was an oil slick. In an hour after washing my face, I could see my face shining with oil. Ugh. Well, I had enough and I decided to try Accutane. That was 3 years ago and it was the best thing I ever did for my skin. I had very little side effects (bloody nose, dry lips, a bit of flaking, redness, flushing) but they all went away and it was easily bearable. It was worth the clear skin and no oil! I would go to my doctor and excitedly tell him, "No oil, no oil, no oil!" It was a miracle drug and I was clear by month 2. I was on 60 mg a day for 5 months. A complete course. Sadly, about 3 months after, my oil started to come back and the acne along with it. You must understand that my oil levels and acne was not as severe as before, but the acne and oil still bothered me. So I went on a 2nd course of Accutane about a year ago. For some reason, the side effects were a lot worse this time. I really thought depression was not a side effect of Accutane but I think now it can be correlated if your skin gets worse. Of course you would be depressed if your skin turns to shit! My lips were dry, my skin was redder than ever, and my skin was super dry. It was a fucking battle for 3 months and then I stopped. I stopped because my skin was clear and the side effects were torture. My doctor says that it was probably because I did not need that much Accutane to control my acne. Truthfully, I had barely any acne (just persistent random whiteheads), but I wanted to take a 2nd course because my oil levels were not to my liking. I was sick of having to wipe away oil every 2 hours and I knew it was the only thing keeping me from clear skin. Then life found me studying in Korea and it was here that I read a study on ultra low dose isotretinoin. It is a study by Dr. Plewig about ultra low dose isotretinoin over a long period of time. His study states that people with oily skin can control their oil levels and acne even with ultra low doses. Enamored by this theory, I went to a Korean derm (more like family doctor) and I asked if I could get a prescription for isotretinoin. So much easier to get it here and they actually have these mini bottles for low dose Accutane prescriptions! I learned that in Korea, people usually take lower doses for a longer period of time rather than blasting the sebaceous glands in five months. Luckily, my doctor was not new to ultra low dosing as many patients in Korea do this to maintain perfect skin...yes we are very vain. He didn't even write me a prescription but ordered me up a bunch of mini Accutane pills (one pill is 10 mg) and told me to take them as I saw fit. He gave me enough to last me years (cost me less than $100). And I don't have to come in every month for blood work! Yes! Thus, begins my journey of 10 mg every 7-10 days. More (I will wait more days) if I feel like it, all up to how my skin reacts. It has been exactly 10 days since I started this experiment and my skin is doing very well. Oil levels seem to be the same, no dry lips yet, pretty much acne free, and feeling great. But this is nothing. I have nothing to offer you guys right now. All I can say is that I am doing this because I feel like ultra low dose Accutane is a viable option for MANY people, but not many people know about it. I hope my log adds to the conversation and sheds more light on this subject. I will keep you guys updated as much as I can and I will keep this log alive until I stop taking this drug. After about a year, I know that I can offer you guys more. I'd rather not take Accutane, but I also refuse to live more of my days with acne. Acne is not only physically scarring but emotionally and socially unhealthy. It fucking sucks. No one deserves acne, it is bullshit. But listen carefully, I also do believe that the best way to solve acne is not with prescriptions, over the counter fixes, BP, SA, cosmetics, cleansers, lotions, etc. I actually firmly believe that acne is caused by hormones and...what we eat! I could write a damn book about why I believe this is so, but let me just say two things: 1. More people have severe acne now than in the past. 2. Studies have found that indigenous tribes that have not been affected by the Western world have zero fucking acne. Some people eat food and get fat and diabetes...others get acne. I got acne and oily skin. Even though I am very skinny, I eat for three people and I have had a huge sugar, carb tooth, fat, and meat tooth. I have won many eating competitions. But reading books on Paleo, Keto, Detox, and especially the "China Study", I started to change my diet for the better. My diet is mainly fruits and veggies. Staying away from eggs, red meat, dairy, sugar, sugary drinks, wheat, breads, cakes, and all that good stuff. I truly believe this has helped me a lot with my general health and even my acne. I like it. It sucks to be nearly vegan but I know it is better for my long term health. If my skin gets clear, it is not only because of isotretinoin, it is also because of my diet. Isotretinoin is my back up and I will try to really live up to the "ultra" in my ultra low dose Accutane experiment. My face regimen: I am sick of all these acne cleansers and lotions. They just cover up the problem that is inside our bodies. They do not do anything for the what is causing our sebaceous glands to produce oil and clog our skins. The only thing I do is clean my hands with Dial soap and use lukewarm to cold water on my skin and clean with Cetaphil Gentle cleanser. Nothing else. No exfoliating. I want to do as little as possible. I am just going to control my diet and take isotretinoin every 10 days or more (if my oil levels drop, I might take just one every month). If you guys have any questions for me, hit me up! My love goes out to all y'all, and a big _|_ to acne. Hehe.
  23. Hey guys. So I recently started the third month of my course on 80 mg/day. I recently visited my ophthalmologist and he said I have blepharitis. It's fine because it's very common on accutane users and supposedly very easy to treat. My only concern is that I just hope it doesn't worsen! Has anyone had any issues with hair loss, particularly eyebrows and eyelashes? I have very thin hair and not an "abundance" of it. I have androgenic alopecia, and it runs in the family. My kind just makes my hair thin over the years and it grows less and less, therefore no bald spots or patches. So by the age of 30, I'm expecting to have a receding hair line :/ Not very cute on a girl. I've noticed that my eyebrows aren't as full as they used to be. I do fill in my brows, but lately I've been noticing that I need to "fill" them in more because they're not growing! When I moisturize my face, I don't really put the cream on my brows, because I know that does clog hair follicles and impairs growth. But Im wondering if anyone has had a similar issue where they noticed loss of hair in eyebrows and eye lashes. I'm freaking out b/c I naturally have very thin hair and it will not get better b/c of my genetic condition. I'm really struggling to preserve every hair I've got while I still have it! Thanks!
  24. hello guys, I'm starting this topic again because it's actually very pertinent to understand the common symptoms between people treated with 5ar inhibitors and the so called :"Post Finasteride Syndrom" I was in my life 4 times treated with Accutane here in Europe (Roaccutane as it is name here). Each cycle last about 9 to 12 months. Now, I have 42 years old and I have very law SHBG levels and accordingly an absence of libido. I went to visit an Endocrinologist who gave me my precise levels of hormones. I train hard everyday at the Gym and did sport my entire life and I don't drink nor smoke. Despite all that efforts and my decent Testosterone Levels, I seem to just lack SHBG don't matter how. Since I remember while I was treater with Accutane I had a f*** hight libido, I investigated the possible side effect of this drug. Hence, I started to understand that like many of you I have the so called "Post Finasteride Syndrom". lost of libido and abscence of natural spontaneous of nocturnal erections. Among other things of course.. I will now try to treat myself with Poviron in order to see whether this might be of a help. FYI, I have never messed up with Steroids or PEDs (Performance Enhancing Drugs) before. I will do this just to understand whether this could possibly increase my Libido. Also, I know what is the dosage to be used and that Proviron will not damage my liver (unlike Accutane).
  25. I completed Accutane a little over two months ago with little to no problems. I was on Accutane for six months, and while on the drug my sex drive slowly started to dwindle, but I was working on graduating college and never connected the dots. Now it's completely gone, as in so desire to have sex AT ALL. This is unlike me and I recently just started researching this side effect in relation to Accutane. Have any other women found a way to overcome this? I have a hard time believing this could actually be a side effect I deal with forever.... my doctor didn't mention anything about this being a possibility.