I used a Clindamycin solution for my moderately severe acne about 10 years ago, and it was a miracle worker for me. After using almost every over-the-counter products, Proactiv and Murad, this stuff did the trick. I had flawless skin and would get tons of compliments, but now it does nothing for me. After years of using this product I've become resistant to it. It no longer works and my acne has flared up again. It is a great product, but just like most medications, your body becomes use to it and no longer does the trick. I would recommend it to people for mild to moderate acne.