I am now on week 2 of Differin, and instead of appyling it every three days, I'm applying it every two. I'm not breaking out as bad, but I am still getting some pimples still. I noticed that the pimples from last week are taking FOREVER to go away. I guess it's because I'm not popping them for once lol. My lips are starting to get a little dry, other than that, no side affects. My skins texture is really improving I would say and I'm not getting as oily. I feel a lot better than I did last week, I know I'm just gonna have to work through this because everything is a process. I will update you next week, because I will start applying it every other day.