Its been three weeks, I can definitely say that this is the best topical acne treatment I have used, across both prescription and over the counter products. This is the clearest my skin has been in years - am actually getting compliments on how healthy and glowy my skin looks! I literally can't stop looking at my skin in the mirror - my pores are smaller, scars and red marks have faded considerably. I was told to keep using as long as I am continuing to see an improvement - so am continuing to apply twice a day after cleansing. It's a very lightweight gel ointment, slight warming effect when it's applied, but it absorbs right away. I then moisturize and apply makeup as usual. I'm maybe halfway through my first 15mL bottle, so it goes a long way!