SO, it's been a year and a half since I started my regimen (Bactrim 800-160 once daily, 25mg Spironolactone, CeraVe facewash, 6months Acanya topical), about 15 months since I started seeing DRASTIC improvement, and one year that I have been totally clear. I have to say, I NEVER imagined this could be possible for my skin. If you've read my previous blogs, you'd know I suffered from severe cystic acne along with cosmetic acne and extremely oily as well as sensitive skin. After 3 months on my regimen, I was overjoyed that my skin had went from 95% broke out (face, chest, arms & back), to about 50%. I would have been happy with that, honestly, because my skin hadn't looked that good in years. But after 6 months I was totally clear. Yes, 100%. I was ecstatic to say the least. Used Atralin (RetinA) to help fade the marks that were still visible but after two more months I had some trouble with sebhorreic dermatitis (basically itchy, dry skin caused by an imbalance of good and bad bacteria) and the Atralin and Acanya were making my skin even more sensitive so the risks outweighed the benefits. It took me about 6 weeks to get the seb derm under cotrol, but (fingers crossed) I haven't had an outbreak in about 8 months, so I think I'm in the clear! As far as my skin goes, I will get MAYBE 1-2 minor blemishes/month and that is purely hormonal. My skin is clearer than the friends I used to envy for their clear skin. I'm ecstatic, I will never take this for granted. Looking into maybe a chemical peel or laser resurfacing to diminish the appearance of pores, but that's unrelated to my past acne, everyone in my family has large pores. I actually don't have ANY scarring from my horrible acne history, it's amazing, I'm so blessed and fortunate. Anyways, all that to say- THERE IS HOPE. Keep trying things. Someday something will work. If you're a female over 20 still suffering from hormonal acne, ask your dermatologist about spironolactone, it's a miracle worker for me. Also, ask about Bactrim (antibiotic) specifically, because unlike other antibiotics it targets the skin first rather than cycling through your entire system. The combination has done wonders for me. Peace and love, God bless.