Today is day 4 on the Isotretinoin. So far pretty descent. My acne is bad but not horrible so I'm hoping for successful results. I'm starting to get dry lips, my voice is hoarse and raspy, and I'm dry around my eyes and mouth. Getting headaches on and off but it's hard to tell if its from the weather or not. I'm still in good spirits and I'm hopeful and patient. I see a behavioral therapist next Wednesday only because I was on depression meds before taking the Isotretinoin.