Leaderboard

Lmao. I like your thinking, and a valid point I suppose lol. On a side note.. I really hope that the research done on FAK is just a branch that spawned out of verteporfin research vs being the result of it. This paper makes it seem like we’re going back into research mode instead of validation of verteporfin efficacy. Other than that, the results are pretty good. The size of those wounds are gigantic it seems, like the size of one whole cheek in humans. But for the excision appro

We 're almost there everyone .... i have dermatitis of eyelids , facial scarring etc ... if this works on humans things will only get better .... everyone scarfree healing will happen sooner rather than later ....

Here are some additional photos that I just took outside today. I didn’t take before photos outside but still thought this might be useful for some people to see what my scar type looks like outside in direct sunlight right cheek right Left left

Here I am at two months post-op. Same harsh lighting. I angled the lighting a little more so people could see the left cheek’s scarring a little better. right cheek Right cheek right cheek notes on right cheek: boxcars still present but slightly softer than before. They are kind of hard to see because they are white in the centre and kind of blend in to some degree left cheek left cheek left cheek And because my thread is so lo

It's happening .... am looking forward to scar free healing being a reality soon <3

"It will take decades" No, it won't: 1) Works on the pigs whose skin is closest to human skin 2) It is already approved by FDA (for eyes) 3) Has big interest from hair loss community

https://www.prdistribution.com/news/burn-injury-healed-with-complete-skin-regrowth-in-only-6-days-using-new-stem-cell-drug/1836901 This seems promising, it solved a third degree burn with minimum scar tissue, a third degree burn goes deeper than the dermis. https://www.biospace.com/article/releases/viaderma-lead-product-tetrastem-shows-promise-in-treating-acne-/ It has been previously used for acne as well, and this mentions about skin regeneration and minimising scarring as well

Yeah, I hope we will get som news by the end of september!

Honestly, shake the haters off. Who cares what any of us think? You spent $6000 for a treatment that most of us (including me) are dying to have! You spent it, made the time commitment for it, made the healing time for it, went through so much for it and that’s something to be so proud of. And it is 100% in your right to share any or no photos. Don’t sweat the small stuff. And all of these comments, this whole website forum, that’s the small stuff. I also want to reinforce the obvious trut

please dont listen to this guy its bullsh1t your improvement is huge and undereverday lighting must be almost invisible to people at converation distance I hope your proud and that money hasnt been a waste in the way of getting inprovement. However you looked great with out without scars

I came just in the nick of time to see someone answer in the way i would have too. I think mysharon confuses these upcoming therapies and devices with the current "scar removal" treatments we have that at best work to make scars harder to see or better match ones skin colour.

Ever heard of Latisse? It's FDA-approved for treating glaucoma, but it's actually better known for its off-label use for eyelash growth and thickening. You don't need FDA approval when something is known to work off label. Cytrellis is seeking FDA approval for scars because most doctors don't even know what micro-coring is, much less whether it works for scarring. You're looking at this all wrong. Fraxel/CROSS/etc. are all *scar removal treatments*. Verteporfin is a *wound healing treatm

https://www.docseducation.com/blog/new-research-opens-door-scar-free-cleft-lip-surgery "The Stanford team has moved forward by using the medication on pigs, which have skin more akin to humans, and the results have been similarly dramatic. Patents have been filed to use verteporfin specifically for reducing scar formation" "The results have been similarly dramatic"

You know verteporfin is literally closest thing we have right now for scarless healing, why would it take decades for it to be approved for scars when it is already in use and is approved by FDA for eyes. Pigs are not mice, they are similar to humans, if it works for them there is a big chance that it will work for humans too. You came here just to say that the closest thing we have right now for scarless healing is decades away, so by your logic we will have nothing for decades. Just leave alre

It doesn't work that way, the existing scar has to be excised first. Dealing with acne scars alone is enough, why are you bringing this wave of negativity with you?

Stanford filed patents earlier this year on using Verteporfin for wound healing and hair follicle neogenesis ----https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2021021607

This “cosmetic” attitude nonsense is worst , even some drs are like whatever , u got some scars so what , despite the fact there are studies how acne scarring affects life of people and also how others perceive you , its awfull . Once it will be proclaimed medical and medical insurance will have to cover this issue then will see improvement in treating acne scarring

Yup. we all feel the same way, to varying degrees. Your improvement is vast, and unless you're super close up or in terrible lighting, in a few of the photos they were so much improved I barely saw them they looked like you had full makeup on to be honest. Of course this is probably painful to hear because you (and me) are constantly in bad lighting on the way out, or we see our flaws every day and know it's bs, and not in the best situations, and everyone around us is perfect even people i

Since the damaged tissue is going to be removed, it would make new wounds anyway so I think it shouldn't make a difference. It shouldn't matter if the skin removed was damaged or perfectly normal before, since the healing process will begin from square one.

No never experienced this personally tbh. I would love to gain some fat in my cheeks lol. Yes it’s offensive IMO when acne scar revision is seen as cosmetic. 100% medical. I wish we could get more support for this condition. I even feel uncomfortable saying I have body dysmorphia because this flaw is 100% real and if left untreated has so many ramifications both mental and social. In Australia I believe you can get certain coverage via insurance for certain acne scar procedures

As far as existing scars and verteporfin goes, I really don’t see much reason why it wouldn’t work. Wounds treated with verteporfin heals without scars. That’s the statement right? So just create a wound. How to create a wound? Well yeah you could just excise the scar, stitch together, and add verteporfin, but that’s kinda lame. Sunogel had a bunch of illustrations on how you cut off the existing scar and deploy hydrogel, and bam scarless healing. You can do the same thing ex

I want to try it on myself, but I'm scared of it

So it will take about 2 years to start human trials? Wonder if someone will try it off label if pig studies goes well…

Why would microcoring even need verteporfin, microcoring should work very good on its own.

They'll figure out a treatment protocol but i personally think that microcoring+verteporfin can work well together for striae and acne scars(if verteporfin works). I'm holding off being too excited about this treatment until pig study results are published.

This is a research paper published by some chinese authors in July. It covers everything regarding skin scarring, everything researchers know by far. YAP inhibition, mechanotransduction, WNT inhibition. I honestly believe there are multiple pathways to achieve scarless regeneration. https://www.mdpi.com/2218-273X/11/8/1095/htm

Punch excision was pretty life changing for me tbh. Check out my thread and let me know if you have questions.

science has made very good progress on how healing works. it will not be surprising if we have a treatment for complete skin regeneration in the near future. be positive!

I still check in once in a while.

I understand your situation @pleasehelp321 but the constant negativity is really harmful for those reading here. It's not all doom and gloom here. It's not right to tell people filler and sub will leave the patient's skin exactly the same that's just not true. If the doctor understands the patient's scar type and recommends the treatment with the skill necessary then it's reasonable that the patient will have improvement. Other factors come into play but to say these treatments don't work is wro

Hello, all! I'm not sure if this has been posted before but has anyone heard about ScarlessWorld Project? It's European funded project with a budget of about 2 million euros. https://cordis.europa.eu/project/id/819933 https://cordis.europa.eu/project/id/819933/reporting (These are their current reports) The end date for this project is 31st March 2024. Good times ahead, I hope.

In my opinion, Shei514 has has great improvement over the past few years. Looking at the pictures she posted just before the phenol peel, I would not even noticed any issues with her cheeks if I had seen her in real life. Congratulations on how far you've come Shei514. I'm still only 6 months into my acne scar journey and every time I lose hope (which is quite often tbh), I log on to this thread and re-read from the start. Again, this message is directed at you Shei514, in my personal o

Hi, I'm almost a month post treatment. Healing well - I think my skin is pretty much back to normal as far as redness, swelling, etc. The scars definitely look better, to me, and so much of the atrophy in my face was fixed really well by the filler. You can still see that I have scars, which doesn't surprise me as I wasn't expecting a "one and done" but I am happy with the improvement and plan to go back for another session with Dr. Rullan.

I don’t know if I want to show my skin in the worst possible lighting because it opens up the conversation to “you’re a poor healer” “you’ve had no improvement.” When the reality is people in real life think I’m crazy for saying I have severe acne scarring. I do not hold a torch to my face and tell people I know to come gawk at me and see every flaw to prove a point. Overhead lighting is useful but it’s not realistic. I’m not going to post photos for a bit, I don’t think I can handle any negativ

Yes this is the issue. The dermatologist should be discussing with the patient what their expectations are long term and if they can’t be met they should decline the patient. I know Lim has talked briefly about this on YouTube about declining patients. If someone with severe scars (like me from the beginning) expects baby smooth skin this will likely never happen. Severe acne scar sufferers have the most emotional pain and the stakes are high. We want to be normal and function in society without

What are you trying to compare it with, are you comparing to a baby face? That is never possible. The aim of all scar treatments is lifting and smoothing the scar to normal skin. So that it doesn’t draw attention. With this procedure of her and filler it will be most undetectable as possible. If you see her comparison pictures you could see her edges have blended in smoothly and remember she is still healing. Her pictures are for reference and she is helping the community as what can be expected

Ok but you are spreading negativity. I spent $6k on this procedure and for someone to say they see no difference that’s extremely hurtful. Those photos were also taken days after the mask came off where the mask left marks on my face. Please stop. If no treatments work and you’ve tried them all just stop and leave this thread.

I’m not here to argue but please do not comment on my thread ever again. If you’re a troll or what I don’t care. All you do is say negative shit and it literally helps no one.

Update 8/18/2021 The procedure went well. Dr. Rullan was very laid back and answered any questions I had in great detail. He also went on tangents for information related to acne scar treatments which I didn't mind I felt it showed his passion for it. side note: he mentioned something about some study on a new type of subcision but I didn't get to ask about it. First he applied some filler, did Phenol Cross, subcision, a bit more filler, then erbium laser finally. The phenol cros

Well it is fda approved... just not for scarring. That's what makes this even more promising. However, we have to wait and see the pig studies. I mean this is a scientific study conducted by researchers that have spent decades on this. Not some company trying to sell you something. So I don't think it is a scam.

Yup it’s deep rolling scar. It think you excision area was huge, is that why this caused? Filler are ideal , look for bellafil. Maybe too much area was excised hence caused a depression but it is a depression with sloping edges. Also it seems like there is tethering still. That is why I always think the lower area for excision the better. You are basically remove a tiny portion of skin permanently so it’s possible that it could create a divot. there are silicon fillers as well if you are i

FS2 was a drug that was supposed to stop fibrosis years back. It sort of worked, but not really. I have not used verteporfin on myself, but what I am saying is id pay for the drug for someone to try on themselves. I do know where to get it, but hesitant on injuring and injecting myself. BUT if someone else wants to try it, I’d pay for their drug and have it shipped to them no joke. otherwise If anyone knows of any forward thinking dermatologists who would be willing to try

Under Porcine and human confirmation of diverging trajectories: «These experiments demon- strated that YAP indeed acts as a master regulator of profibrotic differentiation, and that silencing YAP expression could, like FAK inhibition, promote regenerative EGR1 expression while down- regulating collagen and myofibroblast markers« I believe we should see the results of verteporfin, because i think FAKI just downregulates YAP, but it doesnt block it. What is good is that the researches fo

https://www.nature.com/articles/s41467-021-25410-z Longaker's Lab published the result of pig studies by FAKI inhibition. Please know that Verteporfin is used for YAK inhibition, and it's results aren't out yet. However, FAKI inhibition was undertaken by Gurtner, one of the member involved in the previous mice study in April. I wonder if FAKI inhibition and YAK inhibition will produce different results. This wasn't a complete regeneration, but still an incredible amount of

Make up makes no difference as the scars are atrophic And FYI in most of my pics I’m wearing at best a tinted moisturiser since heavy make up accentuates atrophic scarring Yes I feel that way 100%. It’s very easy to be ungrateful and forgetful it’s only when you take a step back to see everything in context. But it’s still difficult knowing I’ve spent all this money just to look “normal” like not to look better than I do, just normal and so a jealousy sets in when you realise most p

Big update!! Thank you for this.

This is from folliclethought.com which has to do with verteporfin

I didn’t notice any volume loss after the excision procedure. The majority of the excision scars slowly filled in — in the coming weeks after the procedure, which was pretty awesome and self gratifying for me to see, muahahaa. Though it did become harder to keep track of my excision spots with my subsequent treatments (I did fully ablative erbium laser a week after the excision sutures were taken out, then restylane skinboosters (2 syringes) + TCA Cross 90% 1 1/2 month later, then the

UPDATE AUGUST 22nd 2021: I am Flying out of Canada tomorrow to see Dr. Rullan for my August 24 appointment. What’s on the agenda: Phenol cross, blunt cannula subcision, Erbium laser. What I might ask to be added: punch excision to anything that can be excised. photo below is taken yesterday. Going to get some overhead lighting ones taken to update this log. Cheers!

I can’t debunk that claim but I have been seeing some of his work and it’s pretty impressive. But most people say he’s not that good and his results are mediocre at best. It’s all a lighting trick with him. So I wouldn’t really trust anything he has to say TBH (and I get the impression he plays the lighting trick more than other dermatologists). will be interesting to see what others have to say about his claim.