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absolutely. Unbearable. I have no idea how you can live with that. You are strong mfer.

Happy New Year, everyone! I hope we can see something groundbreaking in the new year!

I have a science background nothing to do with this area but from what I can tell the current trial from Mr Chen is just an advancement on from the Verteporfin drug. By means of a way of efficiently applying it and making a feasible economic path onwards. So therefore if the main base of the drug is Verteporfin and that is already FDA approved then the trials change from having to prove it is safe to proving it is effective. This dramatically shortens the time needed for approval, I was wonderin

As many of you know at Stanford Uni there have been some interesting advancements into limiting the human body’s scarring or even remove it completely. They are currently in contact with the FDA about human testing, this will most likely be accepted. However from thins point it usually takes between 6month to 18months. For full permission for production if all goes successfully. I’m currently looking about getting some large excisions before the end of the year however following reading these pr

Lmaoo. It’s weird how emer knows that verteporfin will never be approved or helpful. It’d be better if he said there is no proof or research done with verteporfin and humans, but he goes straight to a definitive no. He’d rather push shitty treatments that are overpriced.

Okay so as I have mentioned previously before I have a science background and so does much of my family one brother as a doctor and a sister as surgeon. This obviously has its benefits, I have recently been studying the verteporfin trials and it’s likely hood of preventing scarring. Obviously the sensible decision would be to wait until the very clever people at Stanford finish it all of and get it FDA approved for the use of scar prevention. However, the drug is available for online purchase, I

Treatment preformed by Dr. Emil Henningsen in early October. First photo was taken before treatment, the second yesterday (3 months after). I had a second treatment right after the “after” photo was taken. I’m very happy with this progress and am optimistic to see how things look further down the line. For reference, these scars are over 6 years old. You won’t find a single doctor without at least one complaint against him. But in my experience I can easily say that Dr. Henningsen abs

Hello all! I wanted to use this section to document my progress phenol peel. I wanted to do this in one go so I don't have to keep checking this website as much. I'll try to post pictures en masse at the 30 day mark. 2014: Acne Scar Journey Begins on a Bad Start: F’ed up big time and went to a plastic surgeon’s office where I was oversold on the care package below. I did get significant improvement but not to the extent that I would’ve liked in relation to the money I spent. I

I was wondering if anyone has any information on the mouse, pig or human verteporfin trials. As was wondering what kinda dosages are expected and how if they say to inject into wound edges is that still applicable to large scale burns.

Good luck and keep us updated

Yes or another friend or something it’s only my leg and a scalpel excision is a very low skill procedure and the personal I’ll speak to about it will have at least 10 plus years of complex surgery so nothing to worry about in terms of knowledge and ability. I probably will go to a plastic surgeon for the face excisions. But other than that I can’t think of a more trustworthy surgeon than someone who really does care about you.

I've been looking into this and the faki hydrogel has been in development since 2017. At least, they have had funds since 2017. There are patents filed since 2019 about using this method. They know what stops scarring, and wanted to repurpose a drug(Verteporfin) so it would be easily accessible. The FAKI research has been before the verteporfin research. The link to the FAKI project summary: https://doctrc.org/wp-content/uploads/2021/08/Gurtner.pdf Hoping that we can see some results

I'm only diagnosed with acne and prurigo nodularis but reserving zero treatment considering how severe my skin diseases are. My whole scalp, body and face are severely affected. I have non healing/stubborn, widespread, deeply embedded, infected, congested,bloody,gooey, dry,itchy painful lesions of scabs and attached plugs, or whatever they are, un every crevice and iy is unbearable . The impeccable and time consuming daily skincare ,hygiene self care that I out in

@NagarNikku_The response reads like a bot wrote it. Dr Chen who is doing the verteporfin trials believes that verteporfin will be available for use in scars in 2-5 years. https://mobile.twitter.com/kellenchen_/status/1452741411057455104

Please don't do 50% tca or cross at home. I'm really advising against it. I've never seen worse outcomes here than at home TCA cross, and it sucks because I've seen beautiful results by professionals. I don't care if one or two members are experts at it. Get TCA cross done in office.

For verteporfin, we only have the mouse study. I don’t think the dosage from the mouse study would be a good reference. I wish the pig study would have been published by now so we would have a clear picture. I don’t know if the wound edges would be applicable to large scale burns but Longaker said he hopes to use this treatment for burns also.

Hi all. I plan on updating this thread for the next month and so on. I took time and realized that scars are a very mentally draining disease and even as a 18yrold guy I’m embarrassed about superficial scars on my face so I’ve finally decided to get something done about this. I’m getting tca cross soon, I hope the results are promising. If I don’t update this thread, it’s probably because I’ve given up and went to therapy instead lol.

They are two different studies. One is the Longaker's study with Verteporfin the other is the Gurtner's study with VS-6062. Do not confound them. The two drugs are similar but they are different molecules. The Verteporfin pig study has not been published yet. Verteporfin is already on the market as Visudyne and can be used Off-label, VS-6062 is not on the market.

I wish you the best. I long for the contacts to have Verteporfin scar revision. Look forward to seeing updates

Even if she's as good as she seems, going to Iran for treatment will be out of question (politically speaking) for many people.

You have two options Tca cross Or Punch excision

Never heard of him screwing someone over like this though. There's only so much a doctor can do, scarring is hard to fix.

It is what is, life is not fair. It never was. You could follow all the rules and still get screwed by life. In our case acne scars.

She is using it like 4 years You guys should see her face its flawless like marble i was look like meth addict more than her.

Thanks to our sub human genetics.

Alright so an update. I'm doing this for anyone who might come across this in the future. I don't recommend using coconut oil. I did some research and it looks like coconut oil is alkalizing while your skin prefers a slightly acidic environment. I gently massaged the spot with Cetaphil then covered it with a band-aid when I went to sleep. Did the same when I went out in public and to work. There are different varieties of Cetaphil, the one I used was "Gentle skin cleanser". Showered on

It just means that they need to cut out the scar before using the drug -- that is, the drug won't dissolve an existing scar if injected into the scar, but if you create a new wound by cutting out the scar, it will heal scarlessly. BTW, that email is not about Verteporfin but a more experimental drug that is a FAKI inhibitor, preventing the body from sensing tension. The end result is similar and the drug could potentially work in combination with Verteporfin for even better results. We

absolutely irrelevant today, but funny still. Remember that PolarityTE hype back in 2017? They are still alive lol https://www.polarityte.com/news-media/press-releases/detail/575/polarityte-announces-submission-of-complete-response-to

Sure you lose your natural elasticity so your skin could look a bit sunken. But deep indents shouldn’t return. Maybe you can expect a bit of more rolling appearance as you age.

Cool stuff. I guess it seems like.. the verteporfin research spawned different teams.. One with FAKI. In which he says the only thing not fully regenerating is the hair. (Which most of us don’t give a **** about). And the other team is working with verteporfin.. if there even is such a group, haven’t heard any word from that side since their original research was published. From a profit perspective, verteporfin doesn’t make much sense to pursue, I’m not sure how patentable t

I think Chen was referring to FAKI, not Verteporfin. Verteporfin could be sooner since its already approved.

We're getting closer , though am looking forward to the hair regeneration also.

Just wanted to add that Stretching the skin is not ideal. The stretched skin is thinner, less vascularized, and it might have a wrinkled or puckered look. so instead of doing this, it would be better to regenerate the skin that should be there. I dunno if verteporfin can do this though. It sounds like they plan on stitching the wound together still, so you Would still have a missing area of skin.

@k95 I could have been lucky with my excisions, in any case it worked for me replacing 2 of my scars with fine lines the only issue being skin tightness. If I were to have smaller scars near these revised they would split under tension. So in theory surgeons could start using tissue expanders however if the skin appears unwounded this would be totally unnecessary and I can only imagine most people would hate having a tissue expander placed in their face for however many weeks/months to achieve e

What does he mean when he says hair/gland isnt 100 %? Is it 90, 50 or 20 %? If it makes the skin look 100 % (which he says), I am sure people will start using it. It is still 100 times better than our options today.

At the moment excision already works, if you have only have one or two scars. The main issue at the moment is if you have multiple scars or the scars cover a large area that the tension on your skin is too great to have successful excisions. Verteporfin won't be that useful if the doctor has to stitch these wounds back up since you're not manufacturing more skin to excise. The skin tension remains. For this to work ideally you'd need to excise the scar tissue and then be able to

I'd just do the subcision but make sure Dr Rullan cuts the tethers in the superficial dermis opposed to the deep dermis. and also suction follow this thread and do the same suctioning this person did: You need to start suctioning once the subcision needle marks are healed AFAIK it takes a day or two. But you ideally want to start suctioning by day 3 after subcision. again make sure your subcision needle marks (wounds) are healed so blood doesn't weep out when you suction. You

Hi ColdHoneydew Any progress on your situation? I have the exact same problem, ( thanks for the excellent pictures). It is somewhat comforting to know someone else is going through the same thing, but sooo frustrating as there doesn't seem to be any answers.

https://www.sciencedaily.com/releases/2022/01/220105111430.htm

I have had problems with my ears and sinuses for a very long-time post Accutane. Idk, I think its this Propionibacterium probiotic that might be helping me. Propionibacterium are a natural colonizer of the gi tract and sinuses. This is getting to my skin too it seems. I see increased oil or "sheen" when I look at my face in the mirror at different angles. If this really was a solution, the logic would be so simple its stupid. Chronic Rhinosinusitis: Potential Role of M

Took Accutane in 2009. 80MGs per day for 7 1/2 months. Was a very happy kid before this chemotherapy. Still feel awful. Low energy. Low everything. Perfect diet for 10 years now. Eyes lips and insides feel like leather. Brain feels empty since. I came here just to post this. You are not alone. The truth is I have been waiting to die since this poison changed my entire life.

Send them a message and ask about individual cases, and if they say like 3 co2 fractionals and full ablative, with 6 subcisions and tca beleive it. But if it ends up as rf microneedling or this magical new laser have your doubts

Yeah subcision is usually helpful. Filler, like Amanda suggested could also help. But often a combination of lots of various things can help. Get under the care of an experienced and trusted scar revision doctor who you really trust.

@Tom_Mason @k95 I have had several sessions of Silicone Microdroplet by Dr. Barry Resnik in Miami to treat my acne scars. I have improved very much but still not completely satisfied with my facial skin. That was after trying a bad C02 fractional laser which despite good intentions, further pushed my indentations and left me with bigger holes. Do you think if this whole new method with verteporfin comes to fruition, this can be done over by Silicone injected facial skin?

idk, I'll go back to this specific bacteria again. Immunomodulation by Bifidobacterium infantis 35624 in the Murine Lamina Propria Requires Retinoic Acid-Dependent and Independent Mechanisms https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660574/ Bifidobacterium longum subsp. infantis 35624 (B. infantis) was originally isolated from resected human healthy gastrointestinal tissue and human clinical studies have demonstrated its efficacy in Irritable Bowel Syndrome patients [15], [16].

I had no bruising for my v beam pie treatment, 3 sessions. First didn't seem to do huge amount, second reduced redness by about 70% seemingly out of no where, maybe the first one was also delayed response, third one didn't do much. overall, very effective at reducing redness massively. took about 2 months.

This is only true if you are a DUDE. if you are a chick, you can always find a man no problems. If you have acne scars as a male it is over. Some day I will get a full face transplant

A little update... it is a slow process. I looked the worst at 6-7weeks post CO2, primers made my skin look horrible. Was very sensitive to touch just to apply a moisturizer. Then it slowly started to improve. At 3-4 months it didn't worry me much anymore. Now, at 6 months, I'm happy with the way my skin looks.