Isotrexin Erythromycin (2%) and Tretinoin (.05%) Gel reviews

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Isotrexin Erythromycin (2%) and Tretinoin (.05%) Gel
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Brand: Isotrexin

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Isotrexin Erythromycin (2%) and Tretinoin (.05%) Gel


Active ingredients:
Erythromycin (2%) and Isotretinoin (0.05%).

Inactive Ingredients:
Hydroxypropylcellulose, butylated hydroxytoluene and ethanol.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

Isotrexin Erythromycin (2%) and Tretinoin (.05%) Gel

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Isotrexin Erythromycin (2%) and Tretinoin (.05%) Gel

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Reviewed on November 1, 2017

used this after panoxyl face wash being discontinued- its the worse thing ever- applied only at night it coats your skin with a plastic layer and makes it so tight its impossible to move your face. I feel because of its gel-like consistency it never really soaks in it just sits on your skin? not nice! would not reccomend!

Awful !
Reviewed on October 23, 2016

Been using this gel for nearly 3 month, due to a manafacturing problem with duac gel i had now been perscribed this gel , didnt have many spots before hand and orginally only got bad spots on my chin area, after using this gel my skin became extremely red and especially my chin and although the spots i have arnt painful as they once were they are now all over my face ! I have had to stop with this gel completely due to my chin being extremely red, dry to the point its so tight it hurt when i move my mouth in a large way, stopped thus gel for around 5 days and bought some E45 which seems to be slowly taking the stubbord dryness away.

After reading many good reviews i was still skeptical to start it but i did start it and cannot say how much i regret this, anyone waring of starting this gel i reccomnded you not to as my experience as a 15 year old girl who once only got larger spots at that time of the month now has them all over her face, and a very painful, dry skin complexion

All in all i would not reccomend starting this gel i once had spots only on my chin and rarely anywere else and now my chin and cheeks are very inflammed, hopefully i can now try to recover my skin

by Muhammad Ali on 11/10/2016 13:22
Isotrexin gel should not be used in Areas of skin affected by eczema. Sunburnt skin. Acne rosacea. Inflammatory rash around the mouth (perioral dermatitis). Women who are pregnant or trying to conceive. Breastfeeding. So be careful guys
by Ann&toby on 10/29/2017 17:06
Where to buy this gel? Please share.
Best retinoid for me
Reviewed on July 29, 2016

Out of all the topical retinoids offered to me through my 12 years with acne this has been the most effective. My acne is extremely resistant to treatment and I've been on Accutane twice but this kept it at manageable levels.

If starting out with this, only use it a few nights a week. It's drying and irritating. Each time I've gone back to using it I've had an extreme initial breakout / purge which is so difficult to deal with but overall it's my favourite topical I go back to again and again.

by AR1995 on 09/06/2016 20:59
Hi, I am 21 male. My doctor prescribed me Isotrexin. I have been using it for two months now. Can you tell me how long does it take before the medication actually starts working? Furthermore, how good is this medicine when it comes to dealing with scars. Thank you.
by Ann&toby on 10/29/2017 16:48
Please advise where to buy isotrexin gel?
It's definitely worth sticking it out!
Reviewed on June 11, 2016

I began having bad ance break outs on my forehead and chin about a year ago, after about 6 months I'd had enough and headed to the doctors, that's when he prescribed me with isotrexin gel. For the first 4-5 weeks my ance got a lot worse! I was having a lot more break outs and my skin was left very sore and dry. After reading lots of reviews I decided to stick it out. I've now been using it for several months and my skin is perfect!! I never have break outs and my scars are fading! I was using it everyday to begin with but I've not cut down to every other day and that works perfect for me. I would really recommend isotrexin! It gets worse before it gets better but it's definitely worth sticking it out!!

by AR1995 on 09/06/2016 20:59
Hi, I am 21 male. My doctor prescribed me Isotrexin. I have been using it for two months now. Can you tell me how long does it take before the medication actually starts working? Furthermore, how good is this medicine when it comes to dealing with scars. Thank you.
by Ann&toby on 10/29/2017 16:49
May I ask where do you buy the isotrexin gel?
Solution for me
Reviewed on May 12, 2016

Suffered from moderate acne since teens. Various contraceptive pills, topical treatments (Duac, Differin), and one course of antibiotics only partially helped. Following a recent breakout I decided to tackle it from all angles, and I think Isotrexin was the key. Also went back on a combined oral contraceptive and took 5-month course of oxytetracycline. Skin cleared up after around 2 months. Having finished the course of oral antibiotics 2 moths ago, skin is still basically spot-free, better than it ever has been.

Initially drying but quickly skin gets used to it. I only apply a very thin layer, once daily, at night.

by AR1995 on 09/06/2016 21:00
Hi, I am 21 male. My doctor prescribed me Isotrexin. I have been using it for two months now. Can you tell me how long does it take before the medication actually starts working? Furthermore, how good is this medicine when it comes to dealing with scars. Thank you.
by Ann&toby on 10/29/2017 16:50
Please advise where to buy the isotrexin gel.
2 weeks in
Reviewed on January 29, 2016

I am a 26 year old female suffering from mild normal acne on my chin and jawline area. I have always had clear skin up until a year ago when I started getting breakouts around my mouth and chin.

In the last year I've tried benzoyl peroxide gel which didn't do anything other than make my skin red and sore and flakey. I then tried a topical liquid antibiotic to apply to the affected area ( I can't remember the name of it). This also didn't work. I then tried lymecycline and took these antibiotics for 3 months - leaving me with clear skin. The doctor wanted me to stop taking them due to effects on my liver. After just a few weeks of stopping them my spots came back.

I went to see a dermatologist and was prescribed isotrexin. I've been told to put a thin layer of the gel over the affected areas at night time after washing my face but before moisturising, so that the product can sink in.

I don't find this product sore or difficult to use. I don't feel any stinging when putting it on like other reviews mention. It dries and goes a little crusty.

I have however (like all the reviews say) had a big breakout. I've gone from just a couple of manageable spots to several at once which I find difficult to hide with make up. I've been using the gel for two weeks and my skin has definitely got worse.

My dermatologist has told me to use it for two months then to go back and see him to review the progress. I will persevere with it until then.

Interestingly he also told me the best face moisturiser to use was aqueous cream which you can buy in huge tubs for only a few pounds. I s water based and oil free and fragrance free etc.

I will add another review once I am at the end no of my two months to let you know how it goes.

by Iioanas on 04/22/2016 21:00
Please do let me know what happens next. I only applied it for a week now, and my acne got worst too. It gets me sick.
by darksoul on 08/13/2017 18:29
same !!!!! can you also detail if you are sleeping with the gel on only or if you're waiting for it to dry then adding moisturiser over the top while you sleep?
by Ann&toby on 10/29/2017 17:07
Please share where to get this gel? Which clinic to buy? Thanks.
Make sure you stick it out!
Reviewed on September 27, 2015

Since I hit my twenties (2 years ago) I have been battling with my skin, something I never thought I would be worrying about having normal skin throughout my teens!

I have tried different anti biotics, the pill, etc and all of them only offer a short term fix.

I would say my acne is moderate which can verge on severe after a flare up but the scars/hyperpigmentation which it leaves behind makes me the most self conscious.

I went to the doctors about a month ago after a really bad flare up and she gave me a combination on isotrex gel, lymecycline and the pill. So far it has got better than it was and I've gone from about 12 active spots down to about 2.

All the reviews are right, it does break you out so bad the first couple of weeks but if you persevere it does get better!

When I apply it it kind of stings and makes my eyes water but within seconds that passes, it also does leave a residue of your face in the morning due to the peeling effect but this can easily be washed off. It does dry out your skin, but so do many acne cream/gels!

After a super bad break out I am finally seeing my skin sort it's self out! I am currently using this before bed after cleansing my face, then using an exfoliator (St ives apricot scrub) some mornings, effeclar duo and lymecycline and the pill.

I am going to carry on with this product for another 4 weeks and see if my skin improves further but so far so good (after the initial breakout)

Hope this helps!


by vic_sxf on 03/04/2016 11:16
scrubbing particles can remove your skin's protective outer layer and make acne worse! My dermatologist has told me. only use Isotrexin in the night and effecter duo+ in the daytime that all.
patience required
Reviewed on September 22, 2015

For this to have any positive outcome you need patience. If you don't have patience then don't bother using it. It will take longer if you have severe acne. I have moderate Anne around the frame of my face inc. Jawline and forehead line plus around the sides of my chin and upper lip. I've been using it for 3 weeks and i can see that my pores are opening up and blackheads coming out more easily. Whiteheads also are coming to the forefront and ironically im also left with a radiant glow. The idea of this gel is to draw out impurities and that's what it does hence the increase in spots at first. The erythromycin is the anti bacterial element which fights the bacteria from living and attacking the sub glands. Small cysts have cleared in a week. I am still getting new smaller spots but i know the gel is drawing out the bugs that having been sitting under my skin. Persevere for minimum 3 months at least before you decide to give up. Good luck

by fms on 10/01/2016 19:56
im using Isotretinion & Erythromycin and completed my first week.. my acne is dry now.. but m having dark spots where i applied the cream.. is it acne burn? what did you experience in first week of this gel?
by AllowedPot on 10/23/2016 18:28
Fms, begin using moisturizer my face become so dry it was painful to move and extremely tight
Pain pain pain.
Reviewed on September 18, 2015

Ok so most of you might not agree with my results or time period using this product but for me it hasn't done any favours.

I have NEVER sufferd with acne as bad this year as I have in the past. A few years a ago I got prescribed "lymacycline" and it did the trick to clear up (or so I think) but this month when I started to develop different signs and more spots than usual I went to the docters for something stronger and he prescribed me this gel "isotrexin".

After reading reviews and not finding many good ones I was willing to give it a go and hope that it would work for me. He did specify that it might take a few weeks to work and now I'm three weeks in I refuse to use this gel anymore.

After reading reviews I took into consideration that my skin may get worse before it for better, skeptical about using it I had a go for the benefit of my face. However, it has made my face red, sore, dry and uncomfortable. The skin doesn't look healthy and looks inflammed and irritated. I have tried to put moisturiser on to stop the flakiness/dry patches under my makeup but my skin would flake and you can still see the scars.

Each day I would wake up with a new painful spot or even a boil under the skin. No matter how much makeup I tried to use it didn't cover or help the situation.

I might not have given it long enough to work but during the 3weeks I used it I was in constant pain and discomfort hence why I decided to stop.

Everyone is different and will react in different ways. At the moment I'm back using my dermologica products and staying clear of any gels or creams prescribed medically.

I hope this don't put you off using it if you do have it, I was just expressing my time whilst using it.

Please feel free to ask me any questions x




by A_tvd123 on 08/17/2016 16:26
I experienced the same as you. However i used i first started using it October 2015-january 2016 and at first it made my skin dry and cleared my face a little bit. After 8weeks i decided to stop using it amd my acne came back much worse. I started using it again last month and have only been using it for 6.5 weeks and my skin is clear now and my acne scars are starting to fade. But when trying for the second time i had worse reactions. My skin burnt like i had been in the sun for too long and went bright red. But after using it for a few weeks the symptoms went and now its all clear.
Might work in the long run
Reviewed on August 30, 2015

I had mild to moderate acne but combination of bad life conditions and habits made it worse. I'm now suffering from moderate to severe acne. I gained weight and I was already prone to pcos. Now I'm diogonised with pcos and I started to take birth control pills. I'm not sure if it's the isotrexin or the pills but my skin is really clearing up. When I first started to use isotrexin, it didn't seem to be working. After 1-2 weeks my skin got worse. I started to have some gigantic pimples that I had rarely had before. I was so upset and I regretted starting the medication. However, after reading some reviews which say it's quite normal at the beginning, I decided to give it a go. Now it's been 3 or 4 weeks since I started to use isotrexin and I can say that there is a dramatic change in terms of acne. All the big, inflamed pimples have become smaller and it is really hard to notice them since they are beneath my skin, not close to the surface. It didn't cause so much irritation. I mean yeah it irritated somehow but it's a quite common symptom in acne topicals. There is only one downside which is the cleaning process. It takes so much time to get rid of the layer it leaves on your skin. I use a face wash called TTO and a lot of water, yet it takes almost 20 minutes to get rid of the gel on my face in the morning. Maybe I should also use a make-up cleaner for that. In conclusion it is really a good topical gel even for severe acne but you must be patient. You will probably breakout more first but it's temporary. Don't forget to apply it only on the legions and it should be a thin layer. I hope this will work for you and you will have the clear skin you are yearning for. Don't make it a big deal though. If you get obsessed with your acne, it only gets worse.

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