It took me 4-5 days for the bruises from the Isolaz treatment to fade. My skin peeled for about 3 days from the Retinol. Although the scars got darker, I hope that's not permanent. I don't see any improvement on the closed comedones yet. The only thing I notice is they tend to surface faster. That could be from the Isolaz suction. I don't draw any conclusion just yet. I heard that it would take 3 treatments to see a result. I'm still hopeful. And I'll update my progress.