After 3 weeks on Accutane I began to see significant results. I didnt get any of the serious side effects. All I've experiences has been chaped lips and slight redness(which could be from being in the sun the past days). My regimen includes 40mg once a day. Since the dose isnt that high i still apply duac at night(mainly to control the "initial breakouts"). For a moisturizer I use the biore nourishing moisturizer plus spf 15 and i also use queen helens mint julep mask for spot treatment. I know my skin can take all these products so i wouldnt recomend them to anyone else unless they too can handle it.