This is my first night on the regimen. I have had acne since I was about 15. I have been on minocycline, tetracycline, bactrim, tazorac, differin, evoclin, and have used the Clinique cleanser system. Almost two years ago I started with tetracycline and Differin. Differin did not work at all for me. The derm said my acne would get worse before it got better, but it never got better. I then got switched to Tazorac and bactrim. I also started using Clinique's facial cleansing system. This combo seemed to work very well for a while. This year the acne came back so I decided to stop taking bactrim. I recently went to the derm and was put on Evoclin for the red pimples and continued to use tazorac for the blackheads. It has been two months and I havenâ€™t seen much improvement. My Clinique was running out and is expensive so I decided that because it wasn't really helping my situation that I'd search the internet for some advice and I landed here on acne.org. I am going to post photos weekly to track my results.