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Charles Lee

IMPORTANT HEALTH INFO - a few OTC ingredients

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"Product ID: NEOSPORIN PRODUCTS

Cage: 09979

Company Name: BURROUGHS WELLCOME CO

Street: 3030 CORNWALLIS ROAD

City: RESEARCH TRIANGLE PARK NC

Zipcode: 27709 US

Health Emergency Phone: 919-758-3436

Date Of Label Review: 12/16/1998

Label Date: 12/16/1998

Hazard And Precautions: POLYMYXIN B

SULFATE-NEUROTOXICITY/NEPHROTOXICITY/NEUROMUSCULAR BLOCKADE/SYSTEMIC

POLYMYXIN POISONING/KIDNEY DAMAGE/SENSITIZATION. NEOMYCIN

SULFATE-HYPERSENSITIVITY REACTIONS/SEVERE RENAL TOXICITY/NEUR

OTOXICITY/OTOTOXICITY/NEUROMUSCULAR BLOCKADE/RESPIRATORY PARALYSIS.

BACITRACIN ZINC-IRRITATION/ALLERGIC REACTIONS (SUPP)POLYMYXIN B

SULFATE-FEVER. NEOMYCIN SULFATE-RASH, HEARING LOSS, DIMINISHED BALAN CE.

BACITRACIN ZINC-IRRITATION. LIDOCAINE-IRRITATION."

"Since ototoxicity and nephrotoxicity have been reported, neomycin and polymyxin B combination should not be used on large areas of the body or for a prolonged period of time. {02} In addition, toxicity may be increased when this medication is used in the treatment of leg ulcers, decubitus ulcers, and otitis externa. {04}

Neomycin-containing preparations commonly cause contact dermatitis. In addition, prolonged use increases the possibility of allergic reactions. {05}

If redness, irritation, swelling, or pain occurs, treatment with neomycin and polymyxin B combination should be discontinued."

Ototoxicity - Having a toxic effect on the structures of the ear, especially on its nerve supply.

Nephrotoxicity - The quality or state of being toxic to kidney cells.

All pertaining to Neosporin and antibacterial creams or ointments with those ingredients in it. You should be careful. It's rare, but it happens. Damage can be permanent.

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