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Isotane/accutane dosage

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If I take 80mg or 4 pills a day, should I take them all at once or 2 in the morn and 2 at night? I've been taking all my pills at once with breakfast but was wondering if it is more effective with a split dose. I noticed that some of you guys do the split dose but my derm never mentioned this to me.

Cheers

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Your body as a whole will not care how you take the pills, but it's possible that your stomach might appreciate the splitting of the dosage. The bigger question is why are you taking four 20mg pills, instead of two 40mg's?

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Your body as a whole will not care how you take the pills, but it's possible that your stomach might appreciate the splitting of the dosage. The bigger question is why are you taking four 20mg pills, instead of two 40mg's?

Thanks for that. We don't get 40mg isotane pills in NZ according to my derm. My stomach seems OK.

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