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Vitamin pills?

I started taking OneADay for men vitamin pills. I was wondering if that would help any with my acne problem. I have alot of red pigmented spots and only like 8 acne on my face...also i wanted to know if they make a salycic acid based cleanser that way i can use the BP and the SA without having to use 2 creams.

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I started taking OneADay for men vitamin pills.  I was wondering if that would help any with my acne problem.  I have alot of red pigmented spots and only like 8 acne on my face...also i wanted to know if they make a salycic acid based cleanser that way i can use the BP and the SA without having to use 2 creams.

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I started taking OneADay for men vitamin pills.  I was wondering if that would help any with my acne problem.  I have alot of red pigmented spots and only like 8 acne on my face...also i wanted to know if they make a salycic acid based cleanser that way i can use the BP and the SA without having to use 2 creams.

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One a day = multivitamin?

The major contributors in helping acne are Zinc,Vit-C,B5,B6,Vit-A,selenium and chromium. Haven't tried the regimen at the bottom so...make your own decisions.

Acne Really Sucks!

Or a treatment regime without all the hype, based on scientific evidence, and after over a decade of research.

Acne vulgaris is a chronic, multi-factor skin condition affecting all ages and involves four pathogenic factors: increased sebum synthesis, hyperkeratinization, microbial proliferation and inflammation. Acne vulgaris consists of what is clinically labeled as non-inflammatory lesions (blackheads, whiteheads, cysts) and inflammatory lesions (papules, pustules, nodules).

Increased sebum synthesis occurs in response to hormones and irritants. There is a hormonal oversensitivity in the skin that starts long before puberty and is suspected to be genetic in origin. Hormonal triggers include increased endogenous androgens, increased endogenous insulin and consumption of exogenous hormones in dairy (possibly red meat). Irritating triggers can include dryness, chemical sensitivities and food intolerances.

Hyperkeratinization occurs when the cells of the pore become cohesive and do not shed normally onto the skin's surface. This may be genetic or this may be in response to sebum gland irritation. The result is a plugged pore called a microcomedome and subsequent lesions which are exacerbated by the next two pathogenic factors.

Microbial proliferation occurs when microbials feed on excess sebum, both on the surface of the skin and/or in plugged pores. Known microbials include bacteria called Propionibacterium acnes, demodicosis mites of the genus Demodex and a fungal-like yeast of the genus Malessezia. A non-inflammatory Malessezia infection of the scalp is commonly known as dandruff.

Inflammation occurs from microcomedomes, microbial proliferation and/or irritated sebum glands.

A major reason why isotretinoin (Accutane) has been the premier treatment for acne vulgaris since it was discovered in the 1970’s is because it directly addresses three of the pathogenic factors above (sebum synthesis, hyperkeratinization, inflammation) and indirectly addresses a fourth (microbial proliferation). No other anti-acne agent can make the same claim. But isotretinoin comes with a high price tag of severe side effects. Many dermatologists will no longer prescribe isotretinoin and fears are it will eventually be forced off the market by the FDA.

Fortunately, there is an alternative regime that works as good as or better than isotretinoin and without the nasty side effects. The topicals are not recommended for those with sensitive skin or acne rosacea! The regime includes the use of lifestyle modifications and the following anti-acne agents:

Pathogenic Acne Vulgaris Factors Targeted by Regime

Lifestyle Modifications

Diet

This is still a controversial topic due to old-school thinking (pre- 1994 era), when widespread medical belief was that nutrition had no effect in preventing or curing disease, and which still persists in dermatology circles today. This outdated belief is slowly changing due to gradually more research on the subject. So what foods to avoid? The evidence at this point recommends eliminating dairy (and possibly red meat) which contains hormones and iodine, sugars and refined grains that increase insulin and/or glucose blood levels, and trans-fatty acids that gunk up the Essential Fatty Acid pathways. Eating “junk food� can no longer be rationalized based on the urban legend of “there is no proven connection between diet and acne�. This phrase is still repeated by well-meaning, but completely ignorant or self-interested companies and individuals who pay no attention to research. So what is the best diet to follow? Out of all of the approaches to date, the Pritikin diet has the best evidence for promoting optimal health as well as being low-insulinic. Use Pritikin as a foundation, drink at least a half ounce of filtered water for each pound of bodyweight per day (soda, tea, coffee, juice and alcohol can not substitute for water), and add on lean protein as needed. Other food triggers may exist due to food intolerances, so omit those triggers from diet once detected. Common food allergens include corn, soy, wheat, dairy, tomatoes, citrus, chocolate and certain nuts and legumes. If detection is too difficult, it is recommended to go on a hypoallergenic elimination diet. As food has been steadily declining in nutritional quality for at least 75 years, it is recommended to fill in the nutritional gaps with a high quality multi-vitamin and mineral supplement. Best is Garden of Life's Living Multi Optimal Formula which is derived from whole foods.

Exercise

Moderate aerobic exercise for 15 minutes, at least five times a week increases capillary capacity, delivery of oxygen to the skin and reduces stress-related hormones. There is no need to over do it as all exercise generates pro-aging free radicals and depletes nutrients. An infrared (not wet) sauna is a great skin detoxifier and alternative to aerobic exercise.

Hygiene

Take a shower and wash your hair at least once a day. Be very careful of conditioners as most are comedogenic. It is recommended to use Nizoral Anti-Dandruff Shampoo which contains an anti-fungal agent, 1% ketoconazole, in combination with the facial cleanser (recommended below) to reduce any Demodex mites and/or Malessezia yeasts on the scalp. An initial loading dose of five days waiting 5 minutes is recommended, then follow the directions on the Nizoral label. If scalp persists with scaliness, flakiness, greasiness and/or dandruff despite intermittent use of both cleansers, then consider obtaining a prescription for an oral anti-fungal agent, itraconazole, from a physician/dermatologist (who can also prescribe a stronger 2% ketoconazole shampoo). Regular shampooing in-between using Nizoral should contain pyrinthone zinc which has less scalp irritation and microbial-resistance than coal tar, selenium sulfide or salicylic acid.

Laundry

Ideally, wear freshly-laundered clothes and change your bed sheets and pillow cases every day, washed in dye- and fragrance-free detergent. But at an absolute minimum, change your pillow case cover every day to avoid recontaminating your face.

Sleep

Enlightened dermatologists refuse to work with acne vulgaris patients that have jobs during late night or the graveyard shift because it is virtually impossible to clear up their acne vulgaris. This is due to the body’s natural hormonal modulation being disrupted. So aim to go to bed at 9PM, but absolutely no later than midnight, and get 8 to 9 hours of sleep. Catch up on missing sleep during weekends. If a sleeping aid is needed, Melatonin at a 500-mcg or lower dose taken at bedtime is recommended. Do not use higher doses as it will be more than what the brain releases naturally for which the long-term consequences are not yet known.

Oral Regime

Due to the unregulated nature and inconsistent quality of the supplement market in the U.S., it is not recommended to purchase brands other than those specifically listed below.

Boswellia

Boswellia serrata is an herb containing several boswellic acids that inhibit the actions of an enzyme called 5-lipoxygenase (5-LOX). 5-LOX along with the COX-2 enzyme metabolize the fatty acid arachidonic acid (AA). AA is present in food such as red meat, egg yolks and dairy. AA is also derived from dihommogamma-linoleic acid (DGLA). DGLA, and its precursor gamma-linoleic acid (GLA), are derived from linoleic acid (LA), an Omega-6 Essential Fatty Acid which is mandatory to be obtained from diet. All foods contain LA, a few GLA, both of which are easily down-converted into DGLA. In simple terms, DGLA is good and AA is bad. For unknown reasons, inhibiting the 5-LOX enzyme from metabolizing AA into pro-inflammatory chemicals drastically reduces sebum synthesis similar to isotretinoin (Accutane). Currently in trials for treating acne vulgaris is a drug called zilueton (Zyflo) which is also a 5-LOX inhibitor like Boswellia, except with potentially serious side effects and a high dosage due to a very short 3-hour half-life.

Boswellia has a short half-life of 6 hours, so the recommended dose is one capsule 3x a day at the beginning of every meal (assuming you eat every 6 hours) which will also help with any side effects of dyspepsia (stomach/heart burn). Do not take along with dairy or calcium supplements as it will inhibit the effectiveness. Best is Nature's Plus's Boswellin standardized to 65% total organic acids and 15% true boswellic acids.

Chromium

90% of Americans are reported to be deficient in chromium due to too much sugars in their diet. Metabolizing sugars rapidly uses up chromium. High blood glucose levels are linked as a cause of acne. It was found that skin with moderate to severe acne vulgaris had insulin insensitivity and/or low glucose tolerance, a hallmark of diabetes. Hence the old term “skin diabetes� that was once applied to acne vulgaris.

Do not take chromium at the same time with zinc as they antagonize each other. Recommended dose is 600mg with a meal, twice a day. There are many forms of chromium on the market with varying degrees of bioavailability, but the safest and least expensive is yeast-derived Puritan’s Pride GTF Chromium.

Ester-C

Vitamin C has a notorious half-life lasting anywhere from 30 minutes to 2 hours. Ester-C is a complex of metabolites that enhance bioavailability and retention of Vitamin C, although there is not a plethora of studies. Bioflavonoids also enhance bioavailability and retention of Vitamin C. The benefits of Vitamin C are widely known and is mandatory to be obtained from diet/supplementation due to genetic mutation. Research shows a minimum of 2500mg of Vitamin C per day is needed to maintain optimal health. But for the purposes of acne vulgaris, Ester-C is useful in combination with Grape Seed Extract to strengthen capillaries and reduce swelling.

Recommended dose is a gradual increase to 1000mg, three times a day in combination with Grape Seed Extract, taken with meals. Best is Puritan’s Pride Ester-C with Bioflavonoids.

Grape Seed Extract

Grape Seed Extract helps stabilize, remove and produce collagen and elastin. It has powerful anti-inflammation properties, reduces telangiectasia (broken capillaries) and acts an anti-histamine.

Recommended dose is 200mg of a 95% standardized extract three times a day in combination with Ester-C, taken with meals. Best is Swanson Superior Herbs Grapeseed Extract which uses LeucoSelect, one of the highest quality extracts in the world.

Lipoic Acid

Lipoic Acid, a sulfur-containing compound, can heal acne scars by activating a transcription factor known as AP-1 which produces enzymes called metalloproteinases. These enzymes digest damaged collagen, erasing wrinkles and scars. Lipoic acid also produces energy in mitochondria making it available for healing. But most importantly, lipoic acid is used in large doses in Europe to treat diabetes as it increases the burning of glucose and circumvents glucose intolerance.

Recommended dose is 300mg per day of the Alpha form, with a meal. Best is Puritan’s Pride Alpha Lipoic Acid softgels.

MSM

Methylsulfonylmethane (MSM), a natural sulfur compound found in all living things, can mediate hormone balance and detoxify skin.

Recommended dose is 2000mg to 3000mg per day, taken with a meal. Best is Puritan’s Pride MSM capsules.

Vitamin A

Vitamin A reduces sebum production and hyperkeratosis of sebaceous follicles. Isotretinoin (Accutane) is a synthetic derivative of Vitamin A so all of the exact same warnings apply, including risk of birth defects. Dosage should not exceed 30,000 IU a day. Levels greater than 10,000-25,000 IU/day may cause congenital deformity, fatigue, headache, dizziness, blurred vision, joint pain, dry lips, scaly dry skin, excessive hair loss, mouth fissures and increased pressure on the brain. Beta Carotene is not Vitamin A and conversion to Vitamin A is strictly limited by the body. Anyone taking very high doses of Vitamin A should do so under the care of a physician and should be used with serum levels as guidance and never during pregnancy! Recommended is water-soluble Mycel Vitamin A.

Vitamin B6

Vitamin B6 aids in hormone metabolism and is also effective for women with premenstrual acne.

Recommended dose is 50 mg twice a day or 100 mg once per day, taken with a meal. Best is Puritan’s Pride B-6.

Vitamin E

Vitamin E helps protect against lipid peroxidation of sebum and may diminish scarring. Many Vitamin E supplements contain either synthetic dl-alpha tocopherol or natural d-alpha tocopherol, either of which will decrease the most important Vitamin E component in the body, gamma-tocopherol. Gamma- and alpha-tocopherols compete for absorption and the body prefers to absorb alpha- over gamma-. A safe Vitamin E supplement will contain at least a 3:1 ratio of natural gamma- to alpha- tocopherols, as well as the beta- and delta- tocopherols, to approximate the natural Vitamin E distribution in food.

Recommended dose is 200 to 400 IU per day, taken with a meal. Best is Source Naturals Gamma-E 400 Complex.

Zinc

Zinc plays a role in processing hormones and may reduce inflammation and heal damaged skin.

Do not take zinc at the same time with chromium as they antagonize each other. Recommended dose is 50mg, once or twice a day, with meals. Best is Nature's Plus's Dyno-Mins Zinc derived from Phytavail food-grown minerals.

Topical Regime

(Twice a Day)

Step 1: Oil-Free Anti-Microbial Cleanser

Despite being in use since the 1920’s, enfeebled benzoyl peroxide only kills 96% of bacteria. The remaining 4% rapidly proliferate and re-colonize the face long before the next facial cleansing. Nor has benzoyl peroxide any known effect on Demodex mites or Malessezia yeasts. There are also nasty side effects: overdryness, persistent redness, accelerated skin-aging, and bleaching of bed sheets and clothes.

Virtually all cleansers for acne vulgaris contain benzoyl peroxide, salicylic acid, Triclosan or just soap/detergent. None of which are remotely close to being broad spectrum, anti-microbial agents. Unfortunately, a truly effective anti-microbial agent chloroxylenol (PCMX), which kills 99.99% of all gram-positive and gram-negative bacteria for up to 12 hours, is not yet available in any product in the mass consumer market in the U.S... However, a few medical supply companies do stock appropriate cleansers that are safe to use on the face. Best is AloeGuard which contains 0.5% PCMX and a skin neutral pH. Moderate to severe acne may respond better to Techni-Care which contains 3% PCMX.

Using warm water, wet an ultra-soft complexion brush and place a small amount of AloeGuard onto brush. Brush face and neck in a gentle rotating fashion to lather and cover all pores. Wash off with warm water and gently pat face dry with a clean towel.

Step 2a: Oil-Free Toner & Exfoliant

Toners are necessary to remove cleanser residue, restore the skin’s pH balance back to slightly acidic (5.5 pH) due to the use of alkaline cleansers (soap, surfactants) and tighten up pores. Best is Olay Daily Facials Clarity, Purifying Toner which features an advanced Dual Hydroxy Complex.

The advanced Dual Hydroxy Complex is a complex of dehydroacetate and 2% salicylic acid. Dehydroacetate is a sebum synthesis reducing agent. Salicylic acid is the one and only Beta Hydroxy Acid. Unlike the Alpha Hydroxy Acids such as Glycolic Acid, salicylic acid is oil-soluble and penetrates below the surface of the skin and into the pore. And unlike benzoyl peroxide which only acts indirectly, salicylic acid is a true anti-hyperkeratinization agent.

Dilute a cotton pad with the toner and gently apply in an upward motion. Cotton balls soak up and waste too much toner. If initial reaction to the salicylic acid is too irritating, use the toner only once a day or every other day, etc. until skin tolerance is achieved, using Witch Hazel as a substitute toner. Allow to dry.

Step 2b: Oil-Free Anti-Hyperkeratinization & Anti-Inflammatory (Optional)

Adapalene is a retinoid derivative like isotretinin, but it is the least irritating member of the topical retinoids family. Adapalene selectively targets nuclear retinoic acid receptors found primarily in the skin and it does not become systemic. As with salicylic acid, it also penetrates below the surface of the skin and into the pore. It is best to have developed skin tolerance to salicylic acid before using adapalene. Adapalene comes in both cream and gel forms, with the cream less irritating than the gel. Adapelene only needs to be applied once a day, preferably at bedtime. Best is Generic Differin which contains 1% adapalene.

Follow tube directions and apply. Allow to dry.

Step 3: Oil-Free Moisturizer & Sunscreen

Skin needs moisture to avoid increasing sebum synthesis due to any dry skin produced by the regime. Moisture is not oil, so even the oiliest skin needs moisture. A sunscreen is mandatory due to the protective barrier being removed by anti-hyperkeratinization agents. Best is Rachel Perry's Calendula-Cucumber Moisturizer which contains anti-inflammatory botanicals, two of the very best moisturizing agents in the world, and a SPF15 sunscreen.

Gently apply moisturizer over face and neck.

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