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RevolutionIsMyName

The folks @ Carley's Clear & Smooth disagree with Dan's

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They seem to disagree with using daily high doses of Benzoyl peroxide gel.

Here's a C/P of a discussion I had with them.

I've been using their product with good results but not using it as they direct. I've been basicly using Dan's regimen along with Carley's wash in the morning, along with my personal regimen in the evening. Check it out.

RE: (About my regimen)

Sounds good, but if I were you I would try to slowly wean yourself off the

Benzoyl peroxide. thanks

RE:

I could try that... but what's the reason for it ?

I figure if I back off I might break out again.

Please explain. :D

Cheers,

RE:

because eventually you will need more and more to get results. and

eventually no results even if you put it on an inch thick. The bacteria

that causes acne build up a resistance to Benzoyl peroxide. that's why as

far as i know ours is the only one that works for most people long term.

the reason the combination is working is our product opens the pores and

allows the Benzoyl peroxide deeper into the skin. Sooner or later you will

have to bite the bullet and put up with the blemishes until your skin can

be helped with our product. We've had some people in your situation go cold

turnkey for 2 months before our product finally worked for them. but now

they have a permanent solution.

Here's what I'd do if i were you. keep doing what you're doing. It's a long

shot but maybe it will still continue to work for you. I hope it does. But

once it stops working. stop using all Benzoyl peroxide or Glycolic

acid for a month. Just use cover ups and allow the bacteria to go back to

their old ways. Then start again with just our product. within another 30

days you will be clear.

Sorry to be so sure about this. Why do we know all this? Because we have

been answering our emails and questioning people and tracking thousands of

results for almost 4 years. We pretty much know what works and what

doesn't. Keep in touch. thanks

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hmm, in the FAQ it states this:

"Q: Will my skin become resistant to the beneficial effect of bp?

A: P. Acnes, the bacteria in acne lesions, can not survive in the presence of oxygen. BP creates oxygen. Therefore, it is physically impossible for this bacteria to develop a resistance. If the regimen works at first, it should always work."

So what is the truth...Sure they're not just trying to sell their product and make the regimen look bad...

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hmm, in the FAQ it states this:

"Q: Will my skin become resistant to the beneficial effect of bp?

A: P. Acnes, the bacteria in acne lesions, can not survive in the presence of oxygen. BP creates oxygen. Therefore, it is physically impossible for this bacteria to develop a resistance. If the regimen works at first, it should always work."

So what is the truth...Sure they're not just trying to sell their product and make the regimen look bad...

I just replied to their email asking the exact thing.

I'll keep you posted with their answer. :-k

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Many bacteria will build up an immunity to anything over a period of time, and I imagine really long-term use of BP is no different, but p. acne isn't tuberculosis or syhpillis for God's sake! Personally, I would look at it like this.....

Dan-has no profit motive at stake

Carley's-a commercial maker of skin care products

Take the latter's advice with a grain of salt.

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they're full of shit... what did you expect them to say? "Yeah sure keep using that regimen and dont buy any of our products."

if they wrote that some other method works better than theirs they'd get fired on the spot. EVEN IF body developes a resistance to BP (although i cant see how it can become resistant to oxygen..) its gonna be many many years from now and you saved yourself a lot of $$$$ and were acne free during this time..so both ways Dan's regimen is worth it.( if it works for you, of course)

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They're either confusing benzoyl peroxide with antibiotic ointments or are misinformed. Acne bacteria can not develop a resistance to bp.

-Dan

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Here's the reply I got. Notice how they keep changing the subject... :^o

As far as our competition, we hope they keep thinking that way. If you put

20 experts or scientists in a room, you will get 20 opinions. There are so

many schools of thought in the acne area that no one really know anything.

We know how BPO works (or at least supposedly works), but we believe there

is more to it. Because we also know that you are, I believe from what

you've told me, a perfect example of someone who keeps needing more to get

results. I'll bet those Benzoyl peroxide ointments worked wonderfully by

themselves when you first started using them. We hear this over and over

again. We've been in communication with thousands of acne sufferers. We

were mystified originally that our product would work almost miraculously

for many people and do nothing for some. What we were interested in was

what made these people it didn't work for, unique. And the one factor that

kept coming up was heavy Benzoyl peroxide use previous to starting our

product. And the ones our product worked immediately for, had not just come

off using Benzoyl peroxide. And the ones who saw results in a few weeks

were using Benzoyl peroxide but not heavily. In fact rarely have we found

another reason for our product not to work except allergies to it and

combining with other acne products. We also noted that if these people who

were using Benzoyl peroxide stayed patient they eventually started seeing

results. but it could take at least 4 to 6 weeks and in the meantime their

acne got worse. Most gave up. For some reason we speculated that the

bacteria were becoming resistant to the Benzoyl peroxide. It's possible

they were driving themselves deeper into the skin to avoid it or the ones

surviving were becoming more resistant to this oxygenating effect. Bacteria

are living organisms. They do adapt. They've found certain types of

bacteria living deep under ice in the Antarctic.

Then the next question almost everyone asks is, why doesn't our product

have a burnout factor or why doesn't the bacteria become resistant? We

believe it is because people who use this once a day only keep it on the

skin for about 30 seconds. With the deep exfoliation the bacteria are

getting hit hard but quick. Rather than trying to destroy the bacteria we

believe our product keeps them under control for another 24 hours. Plus we

also believe that the absorbing nutritional ingredients somehow work to

make the skin better able to fight these bacteria. It is possible that the

Benzoyl peroxide works as a catalyst. No one truly knows. BUT there can be

a burnout factor with our product. If it is used more than once a day. That

is just more evidence that these little bacteria are adapting.

As an example: aspirin has been on the market for well over a 100 years.

Scientists knew it did a lot of good and also some bad things. But until

recently they didn't know why. And there are many who still believe we are

a long way from unlocking the secret to plain old aspirin.

When you get down to bacterial sizes a whole lot of what we think we know

we really don't know. Scientists do a lot of speculating and observing.

They'll note that bacteria will be less active in certain solutions and

more active in other solutions. But not sure why. Most medical

breakthroughs are developed through plant science. First they find natural

ingredients that attack a certain problem, then they will refine that

ingredient to a purer artificial form so that it is unique and sellable.

For example Aspirin comes for the bark of a willow tree. People came to

know that chewing on this bark stopped headaches. Scientists just refined

the active ingredient and a miracle drug was born.

Yes we readily admit that we've turned common thought upside down with our

product. Many dermatologists laugh at our ingredients. But I've been in

their offices and seen the poor people they treat and in our opinion they

really don't have a clue how to treat acne. they don't even understand the

role that allergies have in many skin problems. And giving people with mild

acne dangerous drugs. We have medical doctors children using our product

successfully. Our dentist has 3 kids who were on all the hard stuff, but

now are almost acne free with our products.

here's a note that came in today from one of our customers after we asked

them if this was their first order. We have legions of such fans.

nope, I've bought for about 2 yrs...with a small break when a dermatologist

flipped out when reading the ingredients. I continue to follow directions

and use the product again, with my primary MD's other help, and I no longer

see that dermatologist. A coworker also continues to use the product who

I've kept up to date. Please keep in mind what will so many people will go

through if you ever stop making this product available! =o)

We believe we have a breakthrough product. but nothing can help everyone.

Just continue to experiment and see what works for you. Everyone is

different, so maybe you're the exception.

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Huh! If P-acnes evolved to live in the presence of oxygen it wouldnt *be* P-acnes anymore.

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I have used Carley's Clear for about 2 months, my skin is used to 5%BP and 2.5% is just not enough for me, this is why I keep using benzamicyn which is 5%.

The Carley's Clear stuff is good, it made my skin feel very smooth and good, However, 2.5% or 2%bp isnt enough for me

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Guest fatman_uk
Why do we know all this? Because we have  

been answering our emails and questioning people and tracking thousands of  

results for almost 4 years. We pretty much know what works and what  

doesn't.

WoW!

That's amazing, considering it's different for everyone. Or maybe *THEIR* products are ''skin-universal'', or sumthin.... Not. :-k

They're talkin poop, ignore them, or laugh. I'd say laugh. :D

-Gaz

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I've used Carley's Clear before with limited results. The regimen works the best for me by far. I've purchased all the acne fighters you can think of and they don't compare to the regimen. I'm mixed up in this argument because if people are saying BP will stop working because your body will be immune to it, doesn't that go the same for every other product? I'm suspecting this person tried to sell their product on this site, with alot of acne sufferers like they do on eBay.

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hah carley....I was laughing all the way thru reading their reply...

Ever so often...in between the lines you can almost hear the sales pitch...

but ya....I think carley's sucks....BP works fine.....resistant to oxygen...right.....

:D/

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So they are saying that acne bacteria won't get resistant to their products?

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I've never done like scientific research on any of this, but I can see what the person from Carley's is saying. Bacteria can adapt to things that they deal with all the time. It's evolution, they adapt to their surroundings in order to survive. If acne didn't adapt, nobody would have acne. They're saying that acne won't adapt to be resistant to their product is because the product is only "battling" the bacteria for a short amount of time, thus making the bacteria unable to adapt because it is a foreign invader. Think of it like this:

The desert is dry. The wildlife that lives there can survive in those conditions. The plant and animal life are all able to sustain life in such an arid environment. However, if a normally "moist" place were to have a drought and become as dry as the desert, plant and animal life would die, because it would not be adapted to that environment since it occured so quickly and didn't last forever, just a little bit. But that little amount of time was all it took to make an impact. Same with their product. BP is there a long time, like the dryness of the desert, so life in the desert has adapted to those conditions, just like the bactera adapts to the BP's presence. But if you were in a moist place and it were suddenly to become dry for a little amount of time (Carley's) the impact would be devasting as the life would not be able to deal with the brash change.

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development of resistance over a short period is possible if it involves simple things such as a channel mutation, mutation in importin exportin proteins, mutations in other trans-membrane proteins....

however resistance to oxygen would mean a major change that would affect the entire metabolic pathway. HOWEVER there are other good reasons for development of resistance to bp, like having the bacteria move deeper into skin. while resistance to oxygen is laughable, other factors could help the bacteria escape the wrath of oxygen.

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Bacteria can adapt to things that they deal with all the time. It's evolution, they adapt to their surroundings in order to survive.

I do know a little on this subject and evolving to survive in the presence of oxygen is a major evolutionary jump. In fact the difference is so great we have two groupings for bacteria: anaerobes (killed by oxygen) and aerobes (metabolises oxygen) so the entire metabolic structure would have to change *completely* and you wouldnt have p-acnes anymore!

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Guest fatman_uk

Correct me if im wrong... again...

But doesn't the BP make the oxygen kill the P-Acne SO FAST that they have no chance of ''evolving'' into these super duper resistant bacterias you're talking about? =P~

It seems a similar theory to someone walking round shooting people an expecting that one day soon, people will evolve an develop reactions fast enough to dodge the bullets... it aint gonna happen *tooooo* fast, is it... #-o

-Gaz

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i see your point,but if their product only works for a short period of time then how effective can it be?

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i was more saying the bacteria goes deeper into the skin to avoid the oxygen like the people at carley's said. i know bacteria cannot become resistant to oxygen without a huge mutation thus making them a different bacteria than P. Acnes. but it can still mutate to avoid oxygen.

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i'm no scientist, but i'm pretty sure that the chance of bacteria adopting to oxygen being present in pores is very slim. If it did go deeper wouldnt everyone who uses the regimen get cysts instead of simple whiteheads?

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also- even if the bacteria does evolve to become resistant to bp, Carley's method of hitting them fast should be worse than keeping bp on all day (except maybe for the exfoliation getting it deeper). When it comes to antibiotics at least, hitting fast and nothing else is what causes the resistance (if you don't keep using them long enough to kill everything, what has survived is the stronger more resistnant bacteria).

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Guest fatman_uk

Well... i say fuck Carleys an fuck the science bullshit. I've used nuthin but soap, water an BP for the past year an i'm clear an happy, so i say screw what those corporate lame asses say. :D/

-Gaz

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[Correct me if im wrong... again...

But doesn't the BP make the oxygen kill the P-Acne SO FAST that they have no chance of ''evolving'' into these super duper resistant bacterias you're talking about?

It seems a similar theory to someone walking round shooting people an expecting that one day soon, people will evolve an develop reactions fast enough to dodge the bullets... it aint gonna happen *tooooo* fast, is it...

-Gaz]

in general the way it works is that suppose u have 10 million bacteria, out of those say 2 have a type of mutation in the genetic code that makes them resistant to oxygen. when u use bp all bacteria dies excepts those two. however those two bacteria multiply to a population of 10 million with like 48 hours. so now after 48 hours u have 10 million bacteria, but all resistant to oxygen. this is the general idea of evolution ( ofcourse there is more to it, but this a simplfied version and relative accurate description)

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Thats like saying all of the suddon two humans can respire in space... And then they multiply until every human on earth can respire in space? Why isn't that happenin'

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