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my Derm told me to avoid all alcohol while on Roaccutane. the reason? accutane seriously can mess with your liver. it puts strain on it and it functions less efficiently the entire time you'reon the drug. pair this with alcohol which can put an even larger strain on your liver, even if its just more consistent use and not loads in one go, and your liver might have a tough time managing. personally, that is reason enough for me to not have any alcohol at all when I'mon Roaccutane(and I'm the one with my 18th birthday coming up!). At the end of the day, it's a personal choice though. I'm sure the odd drink will be absolutelyfine, I just don't want to take any chances.