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Cloud83

My first pill

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I have to disagree with the above posters.

40mg per day for someone who weighs 150lbs is roughly 0.5 mg/kg.

That is far below the average dosage for people with cystic acne.

1mg-2mg PER KG is the recommended dosage by the manufacturer.

Again, long term studies have proven lower remission rates with the higher recommended dosage.

Some details you might find in this dermatology thread

http://dermatology.cdlib.org/rxderm-archives/accutane-acne

I'll find the links to the actual studies when I get some break between classes.

Remember the dosage COMPLETELY depends on your body weight. A girl who weighs 100lbs, should not even be in the same ball park range as a guy who weighs 225 lbs.. Keep this in mind when people say they are taking 180mg a day of accutane - they may very well need it.

Cheers,

-Eric

What the hell? 2mg/kg? Do you want to die?

I understand that my 10mg was ridiculously low, and I've been upped to 40mg for the duration now...(not to say I support the topic creator, that's way too much to START with)..but come on.

1mg/kg MAX is what any sensible derm will put you on. Any more is risking, well, your life.

I would say .5mg/kg is sufficient for most severe cases. MAYBE 1mg/kg if it's really bad. That gives you 8-9 months of treatment until cumulative is reached and if necessary can be repeated after the rest period.

What kind of a dumbass would take 2mg/kg? Roche says only in VERY SEVERE cases is that to be used...as in, you can't even make out your eyes from acne.

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You obviously haven't taken the time to read the manual yourself, son.  When rats were given from 1.3 to 5.3x the recommended dose for more than 18months they developed "focal calcification, fibrosis and inflammation of the myocardium, calcification of coronary, pulmonary and mesenteric arteries, and metastatic calcification of the gastric mucosa" 

I don't know what that shit is, but I'm not stupid enough to risk permanent damage by taking the drug in a way unconventional to the way the drug was designed to be administered.  Suite yourself chump.

Okay, right. You don't even know what you're talking about, but supposedly you 'proved me wrong'?. Can't argue there, 'chump', and I use that out of spite.

All seriousness aside, the probability of getting that on higher dosages is probably the same as on lower ones.

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Soldier: I didn't realize your 10mg a day was a startup dosage, you made it seem like you were gonna take 10mg for 2yrs.. I started on 80mg/day and ya it did produce a somewhat dreadful initial breakout; however I am clearing rapidly now in the 4th week and any zit that does form is very weak with little contents. I suppose it depends on the dermatologist and how they want it to play out

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At least I've read the DAMN LEAFLET that comes with the drug. Maybe if you read it, you wouldn't be asking such STUPID questions and you'd have some idea what the hell you were talking about.

Oh, and I'd feel obligated to insult you if you were remotely insulting - that was just weak.

What question did I ask that was stupid? Inform me Dermatologist John, please?

I don't -need- to insult you chief, your posts are clearly capable of doing that all by themselves.

Oh, and I have the booklet, and I've read it through. Currently your statements are out of line with the literature. I'll ask again: What makes you more qualified than a Dermatologist who works -in the field-? Think real hard about this one.

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What question did I ask that was stupid?  Inform me Dermatologist John, please? 

I don't -need- to insult you chief, your posts are clearly capable of doing that all by themselves.

Oh, and I have the booklet, and I've read it through.  Currently your statements are out of line with the literature.  I'll ask again:  What makes you more qualified than a Dermatologist who works -in the field-?  Think real hard about this one.

I'd feel compelled to defend myself if this retort was remotely insulting. This is just weak.

I've never said I was more qualified? LOL! I've never even implied it. Everything I say is from the book and common sense only.

Oh, and 'Dermatologist John'? What a weak, petty, ridiculous excuse for an insult.

Soldier: I didn't realize your 10mg a day was a startup dosage, you made it seem like you were gonna take 10mg for 2yrs.. I started on 80mg/day and ya it did produce a somewhat dreadful initial breakout; however I am clearing rapidly now in the 4th week and any zit that does form is very weak with little contents. I suppose it depends on the dermatologist and how they want it to play out

The reason I advocate a lower dosage is because all my friends who started out on 40mg/day got horrible sides or a few weeks, whereas people who work up to it gradually let their bodies get used to it until they're fine and have less problems.

But hey, if that's working, good for you. Hope you have success with it.

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I'd feel compelled to defend myself if this retort was remotely insulting. This is just weak.

I've never said I was more qualified? LOL! I've never even implied it. Everything I say is from the book and common sense only.

You're giving advice that overrules the known literature on the subject. Your 'common sense' is nothing more than stabbing blindly in the dark. You have no evidence, no studies, no statistics and most importantly of all: none of the medical community to back you up. You don't know what you're talking about, yet you're trying to assume a position of authority on the subject. What makes you qualified to do so?

Oh, and 'Dermatologist John'? What a weak, petty, ridiculous excuse for an insult.

Yes yes, you've covered this ground. But who says it's an insult? I'm sorry if you took it that way, it was more a term of indearment. I do that with all the trolls/flambait I come across on the Internet. But I do understand why'd you see it that way, you do have the mindset that would interpret it that way.

How about I call you 'DJ' instead?

The reason I advocate a lower dosage is because all my friends who started out on 40mg/day got horrible sides or a few weeks, whereas people who work up to it gradually let their bodies get used to it until they're fine and have less problems.

But hey, if that's working, good for you. Hope you have success with it.

So your evidence is 'all my buddies did it this way... so it has to be good' in other words: anecdotal evidence? Not peer reviewed studies? Not field experience? Right, gotcha. You're talking out of your arse.

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You're giving advice that overrules the known literature on the subject.  Your 'common sense' is nothing more than stabbing blindly in the dark.  You have no evidence, no studies, no statistics and most importantly of all: none of the medical community to back you up.  You don't know what you're talking about, yet you're trying to assume a position of authority on the subject.  What makes you qualified to do so? 

Yes yes, you've covered this ground.  But who says it's an insult?  I'm sorry if you took it that way, it was more a term of indearment.  I do that with all the trolls/flambait I come across on the Internet.  But I do understand why'd you see it that way, you do have the mindset that would interpret it that way.

How about I call you 'DJ' instead?

So your evidence is 'all my buddies did it this way... so it has to be good' in other words: anecdotal evidence?  Not peer reviewed studies?  Not field experience?  Right, gotcha.  You're talking out of your arse.

Wow, how pathetic. You're actually typing up book-long responses on an ACNE message board.

I suppose you're username, 'spotguru', kind of shows what a person you already are though.

Again, this is really not worth my time to respond to, but anyway, answer this - are you a doctor? Didn't think so. So, what makes YOU qualified to challenge MY experience of the USE of this drug? I know over 20 people who've used accutane in real life. I don't consider that talking out of my ass. Maybe you do, 'spotguru'.

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Wow, how pathetic. You're actually typing up book-long responses on an ACNE message board.

I suppose you're username, 'spotguru', kind of shows what a person you already are though.

Again, this is really not worth my time to respond to, but anyway, answer this - are you a doctor? Didn't think so. So, what makes YOU qualified to challenge MY experience of the USE of this drug? I know over 20 people who've used accutane in real life. I don't consider that talking out of my ass.  Maybe you do, 'spotguru'.

That was 'book-long'? Oh my tsk tsk tsk. eusa_naughty.gif I'm starting to get the picture now, if a post that took me no longer than five minutes to type is 'book-long' to you... well, shall I just laugh?

As for your new 'concern' - I never challenged your experience champ, I challenged your assumed authority on the subject over the dermatologists and GPs that the people of this board have visited to recieve their medication. You are not more experienced than these GPs and dermatologists, your advice is offered with authority, you are not an authority. Get the picture? 2+2=4? Geddit?

Yes, I have acne so I am posting on an acne board. OMG who'd have thunk it!! Try again DJ.

Lots of love, spotguru.

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That was 'book-long'?  Oh my tsk tsk tsk.  eusa_naughty.gif I'm starting to get the picture now,  if a post that took me no longer than five minutes to type is 'book-long' to you... well, shall I just laugh?

As for your new 'concern' - I never challenged your experience champ, I challenged your assumed authority on the subject over the dermatologists and GPs that the people of this board have visited to recieve their medication.  You are not more experienced than these GPs and dermatologists, your advice is offered with authority, you are not an authority.  Get the picture?  2+2=4?  Geddit?

Yes, I have acne so I am posting on an acne board.  OMG who'd have thunk it!!  Try again DJ.

Lots of love, spotguru.

LOL!

XDXDXD

That was by far the best one yet you've produced...Completely missed the point...Keep 'em coming.

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Guys, can't we all get along. You have different view on what dosage is best and your derms obviously have different methods of practicing. For some people higher doses are better and for some people like myself a lower dose is more effective. Just agree to disagree on this one.

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LOL!

XDXDXD

That was by far the best one yet you've produced...Completely missed the point...Keep 'em coming.

That you don't know what you're talking about? No, I got that just fine. tongue.gif

TMLGirl: Yeah okay, I'm done with this thread.

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Guys, can't we all get along.  You have different view on what dosage is best and your derms obviously have different methods of practicing.  For some people higher doses are better and for some people like myself a lower dose is more effective.  Just agree to disagree on this one.

I am completely with TML on this one, guys. Enough is enough already. You have taken differing opinions and turned it into insult after insult. We're all suffering from this terrible disease and everyone here is just trying to find the best way to treat it. We should try to keep this forum a welcoming and supportive place.

Oh and book-length responses, I think I'm the most wordy poster on this site partially because I can type over seventy words per minute and partially because I am obsessive and have a boring job so no one here is allowed to steal my title - got it! mad.gif

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smile.gifI can type just as fast and too have a boring job w/no supervision where I can be as obsessive and chatty as I want and no one cares! Glad to know im not the only one in my shoes.

Anyways. Im not sure how many kg's I weigh, but im 160 lbs (im 5'10") and im on 80 kgs. I too thought the dose was high but the derm assured me it was according to my weight and not to worry. The breakout was constant for a few weeks but it wasn't THAT bad, I could tolerate it. I think every derm has their own opinion and way of doing it. Either way, I believe if you're uncomfortable w/your derms suggestion then you find a new one. And if you are then you need to trust your derm, like I did. I was told by month 3 that my skin would really take a turn around and its month 2.5 and the breakout has stopped and things are looking good. What is the use and arguing and trying to prove your 'smarts' to eachother? Honestly, the only thing the two of you are doing is making yourselves look extrememly juvenile and immature. Good luck everyone!

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Hey my job is boring too! It's especially slow here at Christmas time. People must think I have no life when I am here for 8 hrs straight. If my boss knew how much time I spent on here, he would not be impressed.

I'm definitely looking forward to not having this silly argument and insult war come to an end. To both of you(Unnamed Soldier and Spotguru): If you need support or just want to vent about your Accutane progress feel free. We all love to help! biggrin.gif

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I edited out some insults. It is okay to have a difference of opinion and debate, but please refrain from the insults. Let's keep this a nice place, okay?

I would like to say you are both right. That is, some people find taking a lower dose for a longer period is best for them as far as side effects or just personal preference. However, it is widely known the higher your dose the longer your remission.

My Dr. wanted me to start at the regular dose for my weight but I convinced her to let me start at a low dose the first month and I am glad I did. It seemed right for me. As it is, I am getting my dose upped tommorrow. eusa_shifty.gif

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Hey my job is boring too!  It's especially slow here at Christmas time.  People must think I have no life when I am here for 8 hrs straight.  If my boss knew how much time I spent on here, he would not be impressed. 

I'm definitely looking forward to not having this silly argument and insult war come to an end.  To both of you(Unnamed Soldier and Spotguru):  If you need support or just want to vent about your Accutane progress feel free.  We all love to help!  biggrin.gif

Hey TMLGirl - just to lighten things up a bit. I got denied permission to enter this site at work anymore cause it got labeled pornography for some strange reason. How embarassing. shock.gif

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Hey TMLGirl - just to lighten things up a bit.  I got denied permission to enter this site at work anymore cause it got labeled pornography for some strange reason.  How embarassing.  shock.gif

Boston: The same exact thing happened to me a few weeks ago but I am able to get in again. I was so upset. I went home and told my fiance that someone on Acne.Org was being a pervert and I couldn't get on.

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[OFFTOPIC]

You can contact your network administrator and tell him to fix that. The firewall or internet proxy might have been incorrectly configured.

In my previous job I was trying to access Univ Of Minnesota web site because I was planning to go to that school and I kept getting denied to go to the site, telling that "content was not appropriate" smile.gif, lol, would you beleive that.

I complained to our network administrator and they fixed the problem...

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Hey TMLGirl - just to lighten things up a bit.  I got denied permission to enter this site at work anymore cause it got labeled pornography for some strange reason.  How embarassing.  shock.gif

That would be embarassing. Thank goodness I work for a very small company (4 people) and no one monitors which sites we visit.

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[OFFTOPIC]

You can contact your network administrator and tell him to fix that. The firewall or  internet proxy might  have been incorrectly configured.

In my previous job I was trying to access Univ Of Minnesota web site because I was planning to go to that school and I kept getting denied to go to the site, telling that "content was not appropriate" smile.gif, lol, would you beleive that.

I complained to our network administrator and they fixed the problem...

I would have trouble justifying visiting an acne support group on my job though. I think our company policy in general is that if it's not educationally related, it's not allowed. It's a school district.

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