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Looks like you have only tried prescription medication for your acne? Have you tried benzoyl peroxide topical medication? In my experience, anything that is prescribed ends up being terrible - it doesn't create a long term solution, and the only long term thing about most are the side effects, which I still suffer from years after I used them. My advice would be to get off of prescription drugs and find a powerful topical medication that you can use consistantly to keep your acne at bay. I don't think you will ever find a "cure" that you will get cleared up and then be able to stop using stuff but at least you can find something that keeps it at bay. BPO works great for most people.