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glb2130

Spiro Ruined My Face

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Not being insensitive i just dont believe it. I am allowed to have my opinion. If its that bad for you though then no reason to keep taking it then.

You're lucky that you don't have these side effects but saying you don't believe we are telling the truth is just ridiculous. why would people lie about this! It was helping my acne so trust me if this face thing didn't happen i would still be taking it. I'm glad that you have a good experience with the drug but drugs obviously effect everyone differently

Now I thought about my boyfriend's comment, that he made some time ago. We looked at my pictures from 1,5 or more years ago and he said that my face was so plump (he personally didn't think the plumpness was cute, but the point is, he saw the difference) and now I thought that my face might have changed after I started taking spiro. The difference is that I've been taking it waaaay longer than the thread's author and it's weird to me, that something would drastically change after just three week, but shit happens... Anyway, this topic made me consider getting off spiro.

As you age you lose volume so that was probably why. It happens to us all ;)
I don't think it's that, not that much aging going on between ages 22 and 24, I hardly have any wrinkles and my parents look youthful in their late 40s. The loss of face volume happened rather quicly for me as well, just not during 3 weeks as the author of this thread experiences. It's easy to track down my pictures.

Btw you shouldn't write down other people's negative experiences with some "simple" explanation. That's insensitive of you... This drug clearly has side effects on a lot of users.

Anyway, sick and tired of spiro and a throbbing pain on my jawline from yet another hormonal breakout doesn't make me encouraged to go through all the dizzy spells and about-to-faint experiences spiro causes me. Why take it, if it doesn't even do it's job - keep me clear.

To the author - well just know that I understand your despair, but all spiro's side effects should be gone once you stop using it, maybe it takes some time while it gets out of your system. Good luck!

Thank you!! Hoping very much everything returns to normal. You're incredibly sweet!!!! Best of luck to you Edited by glb2130
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My theory with spiro and skin changes is two-fold

Factor 1

Remember that there is oil retention and water retention.

You can have oily skin that is also dry--it is oily but does not hold water.

Take away the oil and your skin looks worse because you can see the dryness.

I have noticed this with my skin...anytime I remove oil by any method, my skin cannot hold a normal amount of water. I look older and saggier.

A little bit of oil makes you appear youthful. Oily skin doesn't have to look shiny. You can have oil in a deeper level that sort of plumps the skin a bit. Let's say you're 30 but you have a bit of oiliness that plumps up your face and makes you look 25. You remove the oil and suddenly you've "aged" 5 years.

Factor 2

The other factor is that acne-fied skin is riddled with inflammation. INFLAMMATION PLUMPS THE SKIN.

When I went off Spiro my acne came back. So did some of the oil, plumpness, and redness. Skin quality was worse but I looked a little younger.

Now I am on a new regimen that has reduced my acne again. Guess what...without the constant cycle of inflammation I look older and saggier.

I'm not invested in Spiro anymore, but I have done a lot of research on how it works. I highly doubt that it irreversibly changed your skin quality or permanently aged you. Compared to many other drugs its mechanism is rather simple and its scope is limited. It is far less powerful than Accutane or even your run of the mill birth control pill.

Edited by Green Gables
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My theory with spiro and skin changes is two-foldFactor 1

Remember that there is oil retention and water retention.

You can have oily skin that is also dry--it is oily but does not hold water.

Take away the oil and your skin looks worse because you can see the dryness.

I have noticed this with my skin...anytime I remove oil by any method, my skin cannot hold a normal amount of water. I look older and saggier.

A little bit of oil makes you appear youthful. Oily skin doesn't have to look shiny. You can have oil in a deeper level that sort of plumps the skin a bit. Let's say you're 30 but you have a bit of oiliness that plumps up your face and makes you look 25. You remove the oil and suddenly you've "aged" 5 years.Factor 2

The other factor is that acne-fied skin is riddled with inflammation. INFLAMMATION PLUMPS THE SKIN.

When I went off Spiro my acne came back. So did some of the oil, plumpness, and redness. Skin quality was worse but I looked a little younger.

Now I am on a new regimen that has reduced my acne again. Guess what...without the constant cycle of inflammation I look older and saggier.

I'm not invested in Spiro anymore, but I have done a lot of research on how it works. I highly doubt that it irreversibly changed your skin quality or permanently aged you. Compared to many other drugs its mechanism is rather simple and its scope is limited. It is far less powerful than Accutane or even your run of the mill birth control pill.

Thank you greengables for this! I really appreciate it. I remember reading your spiro post before I even went on it. I've been off spiro for almost 3 weeks and my skin is more hydrated (water) than it was on spiro but the firmness and volume of my face is still not improved, I think it's inflammation/ androgens that were the reason why my skin had been so thick before spiro and now that the androgens are gone my skin seems thinner and more flimsy. The fact that my sex drive is gone too makes me believe that it is androgens. I know it will take some time for it all to come back to normal. If you don't mind me asking what are you doing to control your acne now? If my acne comes back to pre-spiro state I'm not quite sure what to do about it. I actually was looking into getting a high frequency machine (I need to learn how to use it first.) I've had it done in a facial before and it brought down the inflamed cysts pretty fast.

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Now I thought about my boyfriend's comment, that he made some time ago. We looked at my pictures from 1,5 or more years ago and he said that my face was so plump (he personally didn't think the plumpness was cute, but the point is, he saw the difference) and now I thought that my face might have changed after I started taking spiro. The difference is that I've been taking it waaaay longer than the thread's author and it's weird to me, that something would drastically change after just three week, but shit happens... Anyway, this topic made me consider getting off spiro.

As you age you lose volume so that was probably why. It happens to us all ;)

I don't think it's that, not that much aging going on between ages 22 and 24, I hardly have any wrinkles and my parents look youthful in their late 40s. The loss of face volume happened rather quicly for me as well, just not during 3 weeks as the author of this thread experiences. It's easy to track down my pictures.

Btw you shouldn't write down other people's negative experiences with some "simple" explanation. That's insensitive of you... This drug clearly has side effects on a lot of users.

Anyway, sick and tired of spiro and a throbbing pain on my jawline from yet another hormonal breakout doesn't make me encouraged to go through all the dizzy spells and about-to-faint experiences spiro causes me. Why take it, if it doesn't even do it's job - keep me clear.

To the author - well just know that I understand your despair, but all spiro's side effects should be gone once you stop using it, maybe it takes some time while it gets out of your system. Good luck!

Did you notice decrease in sex drive? Mine is just non existent. It happened pretty quickly too, same time as I noticed the change in my face. I've been off for almost three weeks but things are still the same

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My theory with spiro and skin changes is two-foldFactor 1

Remember that there is oil retention and water retention.

You can have oily skin that is also dry--it is oily but does not hold water.

Take away the oil and your skin looks worse because you can see the dryness.

I have noticed this with my skin...anytime I remove oil by any method, my skin cannot hold a normal amount of water. I look older and saggier.

A little bit of oil makes you appear youthful. Oily skin doesn't have to look shiny. You can have oil in a deeper level that sort of plumps the skin a bit. Let's say you're 30 but you have a bit of oiliness that plumps up your face and makes you look 25. You remove the oil and suddenly you've "aged" 5 years.Factor 2

The other factor is that acne-fied skin is riddled with inflammation. INFLAMMATION PLUMPS THE SKIN.

When I went off Spiro my acne came back. So did some of the oil, plumpness, and redness. Skin quality was worse but I looked a little younger.

Now I am on a new regimen that has reduced my acne again. Guess what...without the constant cycle of inflammation I look older and saggier.

I'm not invested in Spiro anymore, but I have done a lot of research on how it works. I highly doubt that it irreversibly changed your skin quality or permanently aged you. Compared to many other drugs its mechanism is rather simple and its scope is limited. It is far less powerful than Accutane or even your run of the mill birth control pill.

Thank you greengables for this! I really appreciate it. I remember reading your spiro post before I even went on it. I've been off spiro for almost 3 weeks and my skin is more hydrated (water) than it was on spiro but the firmness and volume of my face is still not improved, I think it's inflammation/ androgens that were the reason why my skin had been so thick before spiro and now that the androgens are gone my skin seems thinner and more flimsy. The fact that my sex drive is gone too makes me believe that it is androgens. I know it will take some time for it all to come back to normal. If you don't mind me asking what are you doing to control your acne now? If my acne comes back to pre-spiro state I'm not quite sure what to do about it. I actually was looking into getting a high frequency machine (I need to learn how to use it first.) I've had it done in a facial before and it brought down the inflamed cysts pretty fast.

Testosterone does make the skin thicker. I don't remember if it's collagen or exactly what the mechanism is.

Although thicker skin does look more youthful in some ways, I actually preferred my skin on Spiro. The thick skin you get from androgens is inherently masculine--most dermatologists actually call it "coarse" skin.

I found that the testosterone along with a little more oil gave me an "orange peel" look on my nose, cheeks, and chin.

On Spiro, although I looked more gaunt, the actual quality of the skin was more feminine, even toned, and my pores were less noticeable.

I think how my skin looked on Spiro is how it "should" have looked my whole life. But I spent years getting used to a face shape created by skin that was abnormally thick and plump for a female.

I have been off Spiro for a while now and my skin thickness is almost back to the way it was. I look a few years younger. But again, it's not all good, because now I have the enlarged pores look again and it also makes my nose look bigger :(

My regimen now is a lot of Vitamin D, Vitamin A, Betaine HCL and enzymes with each meal, and probably the most important is I am on prescription thyroid medication. I don't know why the thyroid medication helps. My theory is that because I'm hypothyroid (basically my body runs too cold and too slow) that I didn't have enough thyroid hormone for my body to complete basic functions. For example when you're hypothyroid your digestive system is slow, so crap stays in your stomach and intestines longer. Basically everything slows down. Now that I have more thyroid hormone circulating, my body can renew itself faster and things don't clog up my skin as much.

Edited by Green Gables
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Did you notice decrease in sex drive? Mine is just non existent. It happened pretty quickly too, same time as I noticed the change in my face. I've been off for almost three weeks but things are still the same

Well, my sex drive is off quite often, but I'm not sure which one is to blame - spiro or bcp, cause Yasmin is known to decrease libido. So I can't put my finger on spiro on this one unfortunately.

Taking my dose down, btw. Right now I went down from 50 to 37,5 and then I'm going to 25 and will stick to it for a while. Will see if it gives less side effects

Edited by Pianina
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My theory with spiro and skin changes is two-foldFactor 1

Remember that there is oil retention and water retention.

You can have oily skin that is also dry--it is oily but does not hold water.

Take away the oil and your skin looks worse because you can see the dryness.

I have noticed this with my skin...anytime I remove oil by any method, my skin cannot hold a normal amount of water. I look older and saggier.

A little bit of oil makes you appear youthful. Oily skin doesn't have to look shiny. You can have oil in a deeper level that sort of plumps the skin a bit. Let's say you're 30 but you have a bit of oiliness that plumps up your face and makes you look 25. You remove the oil and suddenly you've "aged" 5 years.Factor 2

The other factor is that acne-fied skin is riddled with inflammation. INFLAMMATION PLUMPS THE SKIN.

When I went off Spiro my acne came back. So did some of the oil, plumpness, and redness. Skin quality was worse but I looked a little younger.

Now I am on a new regimen that has reduced my acne again. Guess what...without the constant cycle of inflammation I look older and saggier.

I'm not invested in Spiro anymore, but I have done a lot of research on how it works. I highly doubt that it irreversibly changed your skin quality or permanently aged you. Compared to many other drugs its mechanism is rather simple and its scope is limited. It is far less powerful than Accutane or even your run of the mill birth control pill.

Thank you greengables for this! I really appreciate it. I remember reading your spiro post before I even went on it. I've been off spiro for almost 3 weeks and my skin is more hydrated (water) than it was on spiro but the firmness and volume of my face is still not improved, I think it's inflammation/ androgens that were the reason why my skin had been so thick before spiro and now that the androgens are gone my skin seems thinner and more flimsy. The fact that my sex drive is gone too makes me believe that it is androgens. I know it will take some time for it all to come back to normal. If you don't mind me asking what are you doing to control your acne now? If my acne comes back to pre-spiro state I'm not quite sure what to do about it. I actually was looking into getting a high frequency machine (I need to learn how to use it first.) I've had it done in a facial before and it brought down the inflamed cysts pretty fast.
Testosterone does make the skin thicker. I don't remember if it's collagen or exactly what the mechanism is.

Although thicker skin does look more youthful in some ways, I actually preferred my skin on Spiro. The thick skin you get from androgens is inherently masculine--most dermatologists actually call it "coarse" skin.

I found that the testosterone along with a little more oil gave me an "orange peel" look on my nose, cheeks, and chin.

On Spiro, although I looked more gaunt, the actual quality of the skin was more feminine, even toned, and my pores were less noticeable.

I think how my skin looked on Spiro is how it "should" have looked my whole life. But I spent years getting used to a face shape created by skin that was abnormally thick and plump for a female.

I have been off Spiro for a while now and my skin thickness is almost back to the way it was. I look a few years younger. But again, it's not all good, because now I have the enlarged pores look again and it also makes my nose look bigger :(

My regimen now is a lot of Vitamin D, Vitamin A, Betaine HCL and enzymes with each meal, and probably the most important is I am on prescription thyroid medication. I don't know why the thyroid medication helps. My theory is that because I'm hypothyroid (basically my body runs too cold and too slow) that I didn't have enough thyroid hormone for my body to complete basic functions. For example when you're hypothyroid your digestive system is slow, so crap stays in your stomach and intestines longer. Basically everything slows down. Now that I have more thyroid hormone circulating, my body can renew itself faster and things don't clog up my skin as much.

I so get what you mean about being used to your face looking a certain way. I'm not used to my face having these thin cheeks and I don't like it! I actually think it makes my nose look bigger! I never would have taken spiro if I knew this would happen. It's interesting because my sister who is only 2 years older than me never had any acne problems and she thinks I'm crazy about this but I felt her skin and it's thin, the way mine is now! Makes me think that an androgen factor is definitely there, which made my skin very thick and firm. This article talks about how "male skin" is a lot thicker and says male skin has denser collagen

http://www.dermalinstitute.com/us/library/73_article_Understanding_Male_Skin.html

I also read an article about women with hirsutism and how they had much thicker skin and more collagen I can't find the article now.

I'm going to start taking vitamin A , I lay outside for my vit D because Everytime I've tried a D suppliment I breakout. Right now my skin is calm but it probably won't stay that way for long. For a while I thought I was hypothyroid but tests came back negative and after some suppliments I felt a lot better and more normal, (none of those helped the acne though.) anyway, thank you so much for your input I appreciate it!!

Did you notice decrease in sex drive? Mine is just non existent. It happened pretty quickly too, same time as I noticed the change in my face. I've been off for almost three weeks but things are still the same

Well, my sex drive is off quite often, but I'm not sure which one is to blame - spiro or bcp, cause Yasmin is known to decrease libido. So I can't put my finger on spiro on this one unfortunately.

Taking my dose down, btw. Right now I went down from 50 to 37,5 and then I'm going to 25 and will stick to it for a while. Will see if it gives less side effects

Oh I got it! yeah it could easily be the bcp or the spiro. I just want to be back to normal no more drugs for me ever again! I'm glad you're going down on the spiro if you feel so crappy! It's not worth it Edited by glb2130
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Oh I got it! yeah it could easily be the bcp or the spiro. I just want to be back to normal no more drugs for me ever again! I'm glad you're going down on the spiro if you feel so crappy! It's not worth it

Yea, well anything that lowers testosterone, lowers libido too... But have you thought that in your case it might be a bit psychological as well, because of how you feel about the volume loss on your face?

Edited by Pianina
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Oh I got it! yeah it could easily be the bcp or the spiro. I just want to be back to normal no more drugs for me ever again! I'm glad you're going down on the spiro if you feel so crappy! It's not worth it

Yea, well anything that lowers testosterone, lowers libido too... But have you thought that in your case it might be a bit psychological as well, because of how you feel about the volume loss on your face?

It's definitely the testosterone and not psychological. All my hair is also finer and softer on my arms and legs, no moustache and usually I have to shave it like once a month, even my eyelashes are finer and thinner. I think it's the fact that androgens used to rule my body and now they don't. Don't get me wrong I love the softer hair and the no mustache but the face is thin and mushy and I don't like that. Ateast my acne is still very calm , very little pimples that are go very fast. before spiro I was getting massive puss filled cysts and hard nodules. Yikes ... Can't wait for that all to come back Edited by glb2130

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well it's been almost six weeks since I stopped spiro and there has been no change. No sign of hormones reverting back to normal. My facial skin is very thin and sagged and not how it used to be. I have zero libido which is not normal for me, my hair on my body is rediculously soft (I'll take it.) when do the hormonal effects of this drug wear off? If it wasn't for all the rave about spiro on this site that I had read about, I never would have touched it. I hope that my body reverts back to my normal self soon because this is getting frustrating.

Edited by glb2130
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well it's been almost six weeks since I stopped spiro and there has been no change. No sign of hormones reverting back to normal. My facial skin is very thin and sagged and not how it used to be. I have zero libido which is not normal for me, my hair on my body is rediculously soft (I'll take it.) when do the hormonal effects of this drug wear off? If it wasn't for all the rave about spiro on this site that I had read about, I never would have touched it. I hope that my body reverts back to my normal self soon because this is getting frustrating.

I know this is hard, but try to be patient. My skin used to be a mess, especially in 2013, and now looking back on it 2+ years later, it's soooo much better. But 6 weeks might not be enough to see improvements yet.

It might help to see an esthetician/ dermatologist who can help with treatments to boost collagen in your skin, like vitamin C facials, lactic/aloe vera peels, and high frequency.

For what it's worth, I'm glad you started this thread because it shows that standardized treatments do not work for everyone. It's easy to jump on the bandwagon, but not everyone will react the same...especially to medications NOT meant for acne. Spiro was not designed for acne, just like birthcontrol was not designed for acne, and so on. The same applies to alternative/herbal/ other treatments too, I don't want to be hypocritical since I have jumped on those bandwagons too in the past. I think before starting an acne treatment, we should try to figure out the causes before trying out stuff, especially for women who try these hormonal treatments without being properly diagnosed for hormonal issues to begin with.

So, thank you for sharing and I'm sure some will think twice before taking overhyped treatments.

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well it's been almost six weeks since I stopped spiro and there has been no change. No sign of hormones reverting back to normal. My facial skin is very thin and sagged and not how it used to be. I have zero libido which is not normal for me, my hair on my body is rediculously soft (I'll take it.) when do the hormonal effects of this drug wear off? If it wasn't for all the rave about spiro on this site that I had read about, I never would have touched it. I hope that my body reverts back to my normal self soon because this is getting frustrating.

I know this is hard, but try to be patient. My skin used to be a mess, especially in 2013, and now looking back on it 2+ years later, it's soooo much better. But 6 weeks might not be enough to see improvements yet.

It might help to see an esthetician/ dermatologist who can help with treatments to boost collagen in your skin, like vitamin C facials, lactic/aloe vera peels, and high frequency.

For what it's worth, I'm glad you started this thread because it shows that standardized treatments do not work for everyone. It's easy to jump on the bandwagon, but not everyone will react the same...especially to medications NOT meant for acne. Spiro was not designed for acne, just like birthcontrol was not designed for acne, and so on. The same applies to alternative/herbal/ other treatments too, I don't want to be hypocritical since I have jumped on those bandwagons too in the past. I think before starting an acne treatment, we should try to figure out the causes before trying out stuff, especially for women who try these hormonal treatments without being properly diagnosed for hormonal issues to begin with.

So, thank you for sharing and I'm sure some will think twice before taking overhyped treatments.

Thanks girl. I'm trying hard to be patient. Spiro really takes a hit on hormones and it's really a strong medication. think it's the first medication I've ever taken besides antibiotics so it's weird to feel my body being so different than usual. My dermatologist assures me that things are not permanent but at the end of the day.... No one knows how a certain drug will affect your body and if there will be lasting effects. Everyone reacts differently to drugs. Spiro was a big mistake for me... If more people wrote in negative experiences I definitely would have thought twice about taking it but literally EVERYONE on this site seems to be crazy about this med. and the reviews are generally really good. My acne was getting so bad to the point where I just thought, what have I got to lose?? I thought worst case scenario it wouldn't help my acne. I never expected this mush saggy face thing.. i honestly felt awful when I was on it, I guess it was the dehydration, but I was sooo exhausted . I also had nightmares while I was on it!! I never have nightmares!!! Maybe my body is more sensitive than other peoples bodies but that's nothing I can control. Thank you so much for your advice ,I appreciate it so much. I'm trying to stay positive and hope hat my body is smart enough to revert back to my normal self.

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Thanks girl. I'm trying hard to be patient. Spiro really takes a hit on hormones and it's really a strong medication. think it's the first medication I've ever taken besides antibiotics so it's weird to feel my body being so different than usual. My dermatologist assures me that things are not permanent but at the end of the day.... No one knows how a certain drug will affect your body and if there will be lasting effects. Everyone reacts differently to drugs. Spiro was a big mistake for me... If more people wrote in negative experiences I definitely would have thought twice about taking it but literally EVERYONE on this site seems to be crazy about this med. and the reviews are generally really good. My acne was getting so bad to the point where I just thought, what have I got to lose?? I thought worst case scenario it wouldn't help my acne. I never expected this mush saggy face thing.. i honestly felt awful when I was on it, I guess it was the dehydration, but I was sooo exhausted . I also had nightmares while I was on it!! I never have nightmares!!! Maybe my body is more sensitive than other peoples bodies but that's nothing I can control. Thank you so much for your advice ,I appreciate it so much. I'm trying to stay positive and hope hat my body is smart enough to revert back to my normal self.

I think the hype comes from people who are happy about their acne improvements and post on the forum raving about spiro. However, I noticed that many do mention side effects like weight gain, but they usually emphasize the skin benefits and that's what people on this forum are more concerned with rather than the negatives. In fact, so many take harsh medication like accutane while being well aware of the side effects because they are desperate for their acne to clear at whatever cost to their health. So, I think people weigh the pros and cons, but if the pro is clearer skin, they tend to minimize the cons.

Having said that, compared to other posters, your body seems to be more sensitive than most. But still, the reaction you had could have happened to anyone - and, in fact, the other users I quoted before have had similar reactions so you are definitely not alone. Perhaps you can message them and follow up to see how they are doing and if their face has recovered. I'm sure your face will be fine given some time. The vitamin C and facials I recommended should help speed up the process. You could also look into vitamin E supplements and moisturizers, but I don't have much experience on them.

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Thanks girl. I'm trying hard to be patient. Spiro really takes a hit on hormones and it's really a strong medication. think it's the first medication I've ever taken besides antibiotics so it's weird to feel my body being so different than usual. My dermatologist assures me that things are not permanent but at the end of the day.... No one knows how a certain drug will affect your body and if there will be lasting effects. Everyone reacts differently to drugs. Spiro was a big mistake for me... If more people wrote in negative experiences I definitely would have thought twice about taking it but literally EVERYONE on this site seems to be crazy about this med. and the reviews are generally really good. My acne was getting so bad to the point where I just thought, what have I got to lose?? I thought worst case scenario it wouldn't help my acne. I never expected this mush saggy face thing.. i honestly felt awful when I was on it, I guess it was the dehydration, but I was sooo exhausted . I also had nightmares while I was on it!! I never have nightmares!!! Maybe my body is more sensitive than other peoples bodies but that's nothing I can control. Thank you so much for your advice ,I appreciate it so much. I'm trying to stay positive and hope hat my body is smart enough to revert back to my normal self.

I think the hype comes from people who are happy about their acne improvements and post on the forum raving about spiro. However, I noticed that many do mention side effects like weight gain, but they usually emphasize the skin benefits and that's what people on this forum are more concerned with rather than the negatives. In fact, so many take harsh medication like accutane while being well aware of the side effects because they are desperate for their acne to clear at whatever cost to their health. So, I think people weigh the pros and cons, but if the pro is clearer skin, they tend to minimize the cons.

Having said that, compared to other posters, your body seems to be more sensitive than most. But still, the reaction you had could have happened to anyone - and, in fact, the other users I quoted before have had similar reactions so you are definitely not alone. Perhaps you can message them and follow up to see how they are doing and if their face has recovered. I'm sure your face will be fine given some time. The vitamin C and facials I recommended should help speed up the process. You could also look into vitamin E supplements and moisturizers, but I don't have much experience on them.

yeah you're right! not gonna lie, spiro did help my acne A LOT. i mean... i was only on it for 3 weeks but while i was on it and since then i haven't had 1 big/deep/inflamed/puss filled pimple, which is nice. also the pimples i got on spiro/am getting now don't hurt. testosterone makes the skin oily so by default, if you have less oil, the pimples will be smaller and less painful. now i just get tiny red bumps that aren't anything major, just little red bumps or small whiteheads. before spiro i was getting literally massive cysts. i can't even categorize them as pimples because they were so big lol.

Edited by glb2130
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Hey guys is this theory on spiro correct? Is this the way it works?? The mechanism is still a but of a mystery to me. Different websites say different things. My endo told me that spiro just blocks androgen receptors, but my derm told me it slows androgen productions from the adrenals. I think it does both, but reading a transgender board to get more info on spiro and I came across this explanation which I think (?) is a good one?? What do you guys think ? Is this correct?

" Spiro is actually a general androgen blocker that binds to androgen receptors in your body. The sequestering of available receptors means that T has nowhere to bind, and should make your body think your blood levels of T are higher than they should be-- your body doesn't know that you're taking androgen receptor blockers, the feedback mechanism assumes that T binds to receptors, and whatever is left in the blood isn't really needed above a certain baseline level. Anyway, once the body sees that T levels are higher than necessary, that there's excess in your blood that's not binding to receptors, T production levels should drop"

Edited by glb2130
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Also - am I the only one who has zero libido from spiro? I assume when that goes back to normal my skin will thicken up....and get oily again... I feel like no one says anything bad about spiro ever except for weight gain... Hello people this drug is so freakin weird. ALSO I got my period a few days ago and it's really heavy and my boobs are gigantic! Bigger than they've ever been in my life. My periods always usually super light. It seems like my body isn't moving in the right direction at all since quitting spiro.. Wtf . Sorry for writing so much in here I'm kinda documenting for my own sake . Also I haven't been exercising too much for the past month (bad I know..) is it possible the drugs still in my system? Would running miles help get this drug outta me? :/

Edited by glb2130
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update- no change..... thin sagging skin

my boobs are bigger than ever- they're huge for me... seriously. lmao. that's a positive

Edited by glb2130
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my doctor just put me on Sprio 100mg...it's been two weeks...not much change...it does make me pee a lot and ive increased my water intake because I vape and that tends to make people dehyrdrated...

I've been on Spiro before and can honestly say I've never noticed any difference in my skin as far as appearing older or sagging...it does work for me though...hopefully in a few more weeks i'll notice a difference

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ive been off spiro almost three months and still have zero sex drive , before spiro my sex drive was healthy/high (?). is this normal ?

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Silly one, you don't need a plastic surgeon. Once you start drinking water your face will go back to normal. The bags under your eyes, thinning and dropping are all related back to not enough water intact. You must keep yourself hydrated on Spiro!

ive been off spiro almost three months and still have zero sex drive , before spiro my sex drive was healthy/high (?). is this normal ?

This is my biggest fear apart from old skin and IB. Ugh.

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Silly one, you don't need a plastic surgeon. Once you start drinking water your face will go back to normal. The bags under your eyes, thinning and dropping are all related back to not enough water intact. You must keep yourself hydrated on Spiro!

ive been off spiro almost three months and still have zero sex drive , before spiro my sex drive was healthy/high (?). is this normal ?

This is my biggest fear apart from old skin and IB. Ugh.

no- my skin texture is hydrated.i've been off spiro for over 3 months and my skin is very thin and sagged. it's not because of dehydration, it is hormonal. androgens create a denser, thicker collagen. no androgens = thinner skin. testosterone makes the skin thick. it also gives you a libido and makes your body hair darker. i have no sex drive and my body hair is significantly thinner and lighter than before spiro (not complaing about that, just proving that my hormones have not gone back to pre-spiro state)

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So if the reason for taking Spironolactone is to suppress androgen production in others ways healthy people, why are people not consider doing it safe via diet?

Studies has shown that SHBG can be altered via diet, and testosterone bound to SHBG is ineffective or cannot be bound into dihydrotestosterone(DHT). DHT is the cause of (so called) 'hormonal acne'.

Am I missing something?

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Silly one, you don't need a plastic surgeon. Once you start drinking water your face will go back to normal. The bags under your eyes, thinning and dropping are all related back to not enough water intact. You must keep yourself hydrated on Spiro!

ive been off spiro almost three months and still have zero sex drive , before spiro my sex drive was healthy/high (?). is this normal ?

This is my biggest fear apart from old skin and IB. Ugh.

no- my skin texture is hydrated.i've been off spiro for over 3 months and my skin is very thin and sagged. it's not because of dehydration, it is hormonal. androgens create a denser, thicker collagen. no androgens = thinner skin. testosterone makes the skin thick. it also gives you a libido and makes your body hair darker. i have no sex drive and my body hair is significantly thinner and lighter than before spiro (not complaing about that, just proving that my hormones have not gone back to pre-spiro state)

I'm sure it will go back to normal eventually. Three months is quite long though. I have heard of certain drugs (mosty just anti-depressants) that eventually give you hypo active sexual disorder, but not for this type of drug. Have you spoken to a doctor? I'm worried to go on this medication

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Silly one, you don't need a plastic surgeon. Once you start drinking water your face will go back to normal. The bags under your eyes, thinning and dropping are all related back to not enough water intact. You must keep yourself hydrated on Spiro!

ive been off spiro almost three months and still have zero sex drive , before spiro my sex drive was healthy/high (?). is this normal ?

This is my biggest fear apart from old skin and IB. Ugh.

no- my skin texture is hydrated.i've been off spiro for over 3 months and my skin is very thin and sagged. it's not because of dehydration, it is hormonal. androgens create a denser, thicker collagen. no androgens = thinner skin. testosterone makes the skin thick. it also gives you a libido and makes your body hair darker. i have no sex drive and my body hair is significantly thinner and lighter than before spiro (not complaing about that, just proving that my hormones have not gone back to pre-spiro state)

I'm sure it will go back to normal eventually. Three months is quite long though. I have heard of certain drugs (mosty just anti-depressants) that eventually give you hypo active sexual disorder, but not for this type of drug. Have you spoken to a doctor? I'm worried to go on this medication

I've spoken to the pharmacist , derm, and endocrinologist. They all say it is temporary. I thought I would back to "pre-spiro" (normal me) by now. I'm getting worried

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