I have suffered from severe acne and Rosacea since April 2014. Thanks to God, it has lessened by now. I have always suffered from mild acne since puberty. I became 19 this year and my acne took a horrible form. It only affected my face. I started my regime from 30th March and still am continuing. I started using ISOTREX GEL on cleaned face after using HIMALAYA NEEM FACE WASH and taking DOXYCYCLINE twice a day. My initial break out stage lasted for exactly 6 weeks. Then thanks to God, it started getting less. I stopped DOXYCYCLINE and started taking ACTIVE WHITE GLUTATHIONE PILLS from 9th May. Thanks to God, I break out very less nowadays. From June, I started using GARNIER COMPLETE WHITE NIGHT CREAM. It has helped me with fading my marks. I have always used Sunscreen. From July, I started using RETIN A cream along with ISOTREX cream. I use a very small amount of RETIN A all over my face and neck and I only dab a small portion of ISOTREX gel on the remaining or new break outs. I started using FADE OUT NIGHT cream from tonight. I wash my face at night, then at first I use RETIN A all over my face (a very little amount), then I use FADE OUT NIGHT cream all over my face and finally I use very small amount of ISOTREX on the remaining or new pimples. Thanks to God, I have very few marks and break outs nowadays on my face. ISOTREX is a wonderful gel, it does take a hell lot of time to start working but it DOES WORK! I've now ordered KOJIE SAN SOAP. Let's see how it goes.