ForumsThe RegimenThe RegimenIf You Are Used To ... Notifications Clear all If You Are Used To Strong Topical Creams, Is Your Face More Tolerable To Irritation?steenkash MemberMember0(@steenkash) Posted : 01/17/2014 1:48 pm Hey guys, I been using adapalene (retinoid; highly pure vitamin C). Its a very strong gel, however I need to get prescription for it all the time. I just wanted to know will my face be more tolerable to irritation? Quote Acne Wonderland MemberMember20(@acnewonderland) Posted : 01/17/2014 3:12 pm it probably is, however dont you by any chance notice your skin being somewhat redder overall also? Quote