I have been on doxycycline for about a year now. My acne has calmed down a lot. I typically got it in the "T" zone and along my jaw line...it was more like an capital "I" zone.
I have experience zero direct side effects from the medication. Although one indirect side effect was weight loss. However, I think that is due to the fact that the medication is to be taken an empty stomach. So for me it is 2 hours before a mean and 3 hours after. Being on two 100mg pills a day that means I really cannot eat for around 10 hours a day.
For me it is has been a blessing, however since it did not clear up everything (I still have 3 spots currently, and typically always do), I start a low-ish dose of Accutane on Wednesday.
Yes, I've been on Doxycycline for a year and a half about now with excellent results. Little to no side effects, I had some nausea if I took it on an empty stomach and I have to take Fluconazole once a week as I am prone to yeast infections. Otherwise, I haven't had a pimple for several months now....cystic free and couldn't be happier!