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About a year and a half ago i was using topical Erythromycin (Zinerit) for my acne. Really helped me, cleared it all in a week, but then it stopped working, since i built a tolerance to it.

Now i know that there is a cross-tolerance between erythromycin, clindamycin and probably azithromycin, since they are all from the macrolide group.

My question is, if i've become resistant to topical erythromycin, will taking oral azithromycin (Azatril) have any effect on me?

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No it wont totally different macrolide antibiotics the only thing zithromax is good for in my book is fatigue diarreah and muscle strength decrease these are all inferior antibiotics for acne.tell derm to give u duricef 500 mg twice a day and takeDIRECTLY each time with 400mg ibuprofen and no more acne. btw aczone is much more effective topical then your antibiotic one good luck

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