There are a few scattered case reports of decreased libido with Isotretinoin treatment, but depression itself does cause loss of libido. People with severe acne are often depressed and experience such symptoms prior to taking the drug. Furthermore, people can become more depressed when taking such "drastic" medication.

I don't know about the guy on the show, but how much Isotretinoin did he take and for how long? Did he have clinical depression before the treatment? Was/is he taking anti-depressants? Are you?

In my opinion, it's probably a phsycological side affect of lowered sex drive form the medication rather than a physical one. Low sex drive is a common side effect of depression so perhaps that's the correlation? Hard to say though. Anyone find any studies on this. I for one noticed no difference on accutane.

Sounds crazy, but its had the opposite effect on me. I haven't seen much improvement yet in my skin, but my confidence has gone up a bit just by the fact that I'm positive that I'm on the road to permanent clearance. Makes the hubby much happier after 2 1/2 months of self loathing though, lol!

In my opinion, it's probably a phsycological side affect of lowered sex drive form the medication rather than a physical one. Low sex drive is a common side effect of depression so perhaps that's the correlation? Hard to say though. Anyone find any studies on this. I for one noticed no difference on accutane.

 

I just found a case report on six men with erectile dysfunction, but that is all. The authors thought it was either a correlation or a very rare side effect, but they couldn't rule out the latter. I don't know if there will be more investigators seriously tackling this subject anytime soon, though. Most of the new published research has been devoted to IBD, brain changes and the drug.