Jump to content
Acne.org
Search In
Find results that contain...
Find results in...
borie88

Accutane Causes Depression Of Pituitary-Thyroid-Adrenal Hormones In Even Short Term

Recommended Posts

It was recently showed that isotretinoin decreases insulin-like growth factor-1 [growth hormone]. Increased IGF-1 in adulthood is probably the main cause of persistent adult acne and increased risk of prostate, breast and colorectal cancers [it slowly becomes clear that "acne" is not just a cosmetic problem]. I know that Isotretinoin is harsh and very systemic drug, but it might actually prevent cancer in susceptible individuals by lowering serum IGF-1.

But obviously much safer way of lowering IGF-1 is good diet and insulin sensitizing agents.

Very interesting article here: http://www.ncbi.nlm....les/PMC3141390/

Edited by VanceAstro

Share this post


Link to post
Share on other sites

Yes, it increases the sex hormone binding globulin (SHBG) along with lowering testosterone levels. This is seen as the primary way it gets rid of oil production

Share this post


Link to post
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.


  • Personalized Advice Quiz - All of Acne.org in just a few minutes

×